Effects of Daprodustat, a Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor on Anemia Management in Japanese Hemodialysis Subjects - Akizawa, Tadao; Tsubakihara, Yoshiharu; Nangaku, Masaomi; Endo, Yukihiro; Nakajima, Hiromu; Kohno, Tomoko; Imai, Yukiko; Kawase, Natsumi; Hara, Katsutoshi; Lepore, John; Cobitz, Alexander (American journal of nephrology, 2017)
Keywords: Aged; Anemia - drug therapy; Anemia - etiology; Barbiturates - pharmacology; Barbiturates - therapeutic use; Dose-Response Relationship, Drug; Double-Blind Method; Erythropoietin - blood; Female; Glycine - analogs & derivatives; Glycine - pharmacology; Glycine - therapeutic use; Hemoglobins - analysis; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases - antagonists & inhibitors; Japan; Male; Middle Aged; Prolyl-Hydroxylase Inhibitors - pharmacology; Prolyl-Hydroxylase Inhibitors - therapeutic use; Renal Dialysis; Renal Insufficiency, Chronic - blood; Renal Insufficiency, Chronic - complications; Renal Insufficiency, Chronic - therapy; Treatment Outcome; Vascular Endothelial Growth Factor A - blood