Probing Stemness and Neural Commitment in Human Amniotic Fluid Cells

• Published in: Stem cell reviews Vol. 6; no. 2; pp. 199 - 214
• Main Authors: Jezierski, Anna, Gruslin, Andree, Tremblay, Roger, Ly, Dao, Smith, Cathie, Turksen, Kursad, Sikorska, Marianna, Bani-Yaghoub, Mahmud
• Format: Journal Article
• Language: English
• Published: New York Humana Press Inc 01.06.2010; Springer Nature B.V
• Subjects: Amniotic fluid; Amniotic Fluid - cytology; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Blotting, Western; Cell Biology; Cell Differentiation - genetics; Cell Differentiation - physiology; Cell Line; Cells, Cultured; Female; Flow Cytometry; Homeodomain Proteins - genetics; Homeodomain Proteins - metabolism; Humans; Immunohistochemistry; Intermediate Filament Proteins - genetics; Intermediate Filament Proteins - metabolism; Keratin-8 - genetics; Keratin-8 - metabolism; Life Sciences; Models, Biological; Nanog Homeobox Protein; Nerve Tissue Proteins - genetics; Nerve Tissue Proteins - metabolism; Nestin; Octamer Transcription Factor-3 - genetics; Octamer Transcription Factor-3 - metabolism; Pregnancy; Regenerative Medicine/Tissue Engineering; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; SOXB1 Transcription Factors - genetics; SOXB1 Transcription Factors - metabolism; Stem Cells; Stem Cells - cytology; Stem Cells - metabolism; SOX2; Brain; Regenerative medicine; Neurogenesis; Notch; Stem cells

Recently, human amniotic fluid (AF) cells have attracted a great deal of attention as an alternative cell source for transplantation and tissue engineering. AF contains a variety of cell types derived from fetal tissues, of which a small percentage is believed to represent stem cell sub-population(s...