Gastric microbiota composition in patients with corpus atrophic gastritis

• Published in: Digestive and liver disease Vol. 53; no. 12; pp. 1580 - 1587
• Main Authors: Conti, Laura, Borro, Marina, Milani, Christian, Simmaco, Maurizio, Esposito, Gianluca, Canali, Giulia, Pilozzi, Emanuela, Ventura, Marco, Annibale, Bruno, Lahner, Edith
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.12.2021
• Subjects: Achlorhydria - metabolism; Achlorhydria - microbiology; Adult; Aged; Aged, 80 and over; Atrophic gastritis; Case-Control Studies; Cross-Sectional Studies; Female; Firmicutes - isolation & purification; Gastric microbiota; Gastritis, Atrophic - microbiology; Gastrointestinal Microbiome; Humans; Hypochlorhydria; Male; Middle Aged; Precancerous Conditions - microbiology; Precancerous Conditions - pathology; Risk Assessment; Stomach Neoplasms - microbiology; Stomach Neoplasms - pathology; Streptococcus; Gastric microbiota; Hypochlorhydria; Streptococcus; Atrophic gastritis

In corpus atrophic gastritis (CAG), hypochlorhydria makes plausible the overgrowth of intragastric bacteria, whose role in gastric carcinogenesis is under debate. To characterize the antrum/corpus composition of the gastric bacterial microbiota in CAG patients compared to controls without CAG. A cro...