Palladium- and nickel-catalyzed cascade enantioselective ring-opening/coupling reactions of cyclobutanones

• Published in: Chemical communications (Cambridge, England) Vol. 59; no. 23; pp. 3373 - 3382
• Main Authors: Cao, Jian, Xu, Li-Wen
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 16.03.2023
• Subjects: Cascade chemical reactions; Chemical reactions; Coupling (molecular); Covalent bonds; Cyclic compounds; Cycloaddition; Ductile-brittle transition; Enantiomers; Ketones; Natural products; Nickel; Organic chemistry; Palladium; Ring opening; Transition metals

The chemistry of small ring compounds is an intriguing subject in organic chemistry. As the smallest stable cyclic aliphatic ketones, cyclobutanones have garnered tremendous attention owing to their intrinsic high reactivity such as transition-metal catalyzed C-C bond cleavage. In this context, tran...