Common variants of genes encoding TLR4 and TLR4 pathway members TIRAP and IRAK1 are effective on MCP1, IL6, IL1β, and TNFα levels in type 2 diabetes and insulin resistance - Degirmenci, Irfan; Ozbayer, Cansu; Kebapci, Medine Nur; Kurt, Hulyam; Colak, Ertugrul; Gunes, Hasan Veysi (Inflammation research, 2019)
Keywords: Adult; Aged; Case-Control Studies; Chemokine CCL2 - blood; Correlation analysis; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - genetics; Diabetes Mellitus, Type 2 - metabolism; Disruption; Enzyme-linked immunosorbent assay; Etiology; Female; Genes; Genetic diversity; Genetic variance; Genotype; Genotyping; Gold; Health risks; Humans; Hyperglycemia; IL-1β; Immune system; Inflammation; Inflammatory response; Insulin; Insulin resistance; Insulin Resistance - genetics; Interleukin 1; Interleukin 6; Interleukin-1 Receptor-Associated Kinases - genetics; Interleukin-1beta - blood; Interleukin-6 - blood; IRAK protein; Male; Membrane Glycoproteins - genetics; Middle Aged; Monocyte chemoattractant protein 1; Pandemics; Polymorphism, Single Nucleotide; Receptors, Interleukin-1 - genetics; Single-nucleotide polymorphism; TLR4 protein; Toll-Like Receptor 4 - genetics; Toll-like receptors; Tumor Necrosis Factor-alpha - blood; Tumor necrosis factor-α; Type 2 diabetes; Insulin resistance; Inflammation; IRAK1; TLR4; TIRAP