Systematic Review and Meta-analysis of Pirfenidone, Nintedanib, and Pamrevlumab for the Treatment of Idiopathic Pulmonary Fibrosis

• Published in: The Annals of pharmacotherapy Vol. 55; no. 6; p. 723
• Main Authors: Di Martino, Enrica, Provenzani, Alessio, Vitulo, Patrizio, Polidori, Piera
• Format: Journal Article
• Language: English
• Published: United States 01.06.2021
• Subjects: pirfenidone; all-cause mortality; forced vital capacity; meta-analysis; nintedanib; idiopathic pulmonary fibrosis; pamrevlumab; systematic review

The comparative efficacy of pirfenidone, nintedanib, and pamrevlumab in slowing the rate of forced vital capacity (FVC) decline and mortality in patients with idiopathic pulmonary fibrosis (IPF) is unknown. To perform a systematic review and meta-analysis (MA) of these drugs for IPF. We searched CEN...