The Role of Intravenous Anesthetics for Neuro: Protection or Toxicity?

• Published in: Neuroscience bulletin Vol. 41; no. 1; pp. 107 - 130
• Main Authors: Wang, Kaixin, Wang, Yafeng, Zhang, Tianhao, Chang, Bingcheng, Fu, Daan, Chen, Xiangdong
• Format: Journal Article
• Language: English
• Published: Singapore Springer Nature Singapore 01.01.2025
• Subjects: Anesthetics, Intravenous - adverse effects; Anesthetics, Intravenous - pharmacology; Animals; Central Nervous System - drug effects; Dexmedetomidine; Humans; Neuroprotective Agents - pharmacology; Neurotoxicity Syndromes - prevention & control; Propofol; Review; Neuronal injury; Neuroprotection; CNS; Neurotoxicity; PNS; Intravenous anesthetics

The primary intravenous anesthetics employed in clinical practice encompass dexmedetomidine (Dex), propofol, ketamine, etomidate, midazolam, and remimazolam. Apart from their established sedative, analgesic, and anxiolytic properties, an increasing body of research has uncovered neuroprotective effe...