YTHDF1 gene polymorphisms and neuroblastoma susceptibility in Chinese children: an eight-center case-control study

• Published in: Journal of Cancer Vol. 12; no. 8; pp. 2465 - 2471
• Main Authors: Liu, Jiabin, Cheng, Jiwen, Li, Li, Li, Yong, Zhou, Haixia, Zhang, Jiao, Li, Suhong, Xia, Huimin, He, Jing, Yang, Zhonghua
• Format: Journal Article
• Language: English
• Published: Australia Ivyspring International Publisher Pty Ltd 01.01.2021; Ivyspring International Publisher
• Subjects: Age; Bladder cancer; Cancer therapies; DNA methylation; Gene expression; Genotype & phenotype; Medical prognosis; Metastasis; Neuroblastoma; Pediatrics; Regression analysis; Research Paper; Risk factors; Transcription factors; Tumorigenesis; Tumors; YTHDF1; m6A modification; polymorphism; neuroblastoma susceptibility

Neuroblastoma is one of the most common life-threatening extracranial tumors that mainly occurs in children, and its genetic etiology remains largely obscure. RNA m6A modification has been thought to play a key role in cancer progression. is the critical downstream gene by which RNA m6A modification...