Alterations of the serum N-glycan profile in female patients with Major Depressive Disorder

• Published in: Journal of affective disorders Vol. 234; pp. 139 - 147
• Main Authors: Boeck, Christina, Pfister, Sophia, Bürkle, Alexander, Vanhooren, Valerie, Libert, Claude, Salinas-Manrique, Juan, Dietrich, Detlef E., Kolassa, Iris-Tatjana, Karabatsiakis, Alexander
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2018
• Subjects: Childhood sexual abuse; DSA-FACE; Inflammation; Major Depressive Disorder; Serum N-glycan profile; Childhood sexual abuse; Inflammation; DSA-FACE; Serum N-glycan profile; Major Depressive Disorder

Glycans are short chains of saccharides linked to glycoproteins that are known to be involved in a wide range of inflammatory processes. As depression has been consistently associated with chronic low-grade inflammation, we asked whether patients with Major Depressive Disorder show alterations in th...