Huntington's Disease like 2 presenting with isolated Parkinsonism

• Published in: Journal of the neurological sciences Vol. 373; pp. 105 - 106
• Main Authors: Vasconcellos, Luiz Felipe Rocha, Macêdo, Philippe Joaquim Oliveira Menezes, Franck, Jéssyca Botelho, Tumas, Vitor, Marques Júnior, Wilson, Spitz, Mariana
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.02.2017
• Subjects: Adult; African Continental Ancestry Group - genetics; Chorea - complications; Chorea - diagnosis; Chorea - genetics; Chorea - physiopathology; Cognition Disorders - complications; Cognition Disorders - diagnosis; Cognition Disorders - genetics; Cognition Disorders - physiopathology; Dementia - complications; Dementia - diagnosis; Dementia - genetics; Dementia - physiopathology; Diagnosis, Differential; Heredodegenerative Disorders, Nervous System - complications; Heredodegenerative Disorders, Nervous System - diagnosis; Heredodegenerative Disorders, Nervous System - genetics; Heredodegenerative Disorders, Nervous System - physiopathology; Humans; Huntington's Disease; Huntington's Disease like 2; Male; Parkinsonian Disorders - diagnosis; Parkinsonian Disorders - etiology; Parkinsonian Disorders - genetics; Parkinsonian Disorders - physiopathology; Parkinsonism; Pedigree; Phenotype; Parkinsonism; Huntington's Disease; Huntington's Disease like 2

•HDL2 is the most common HD phenocopy and it is usually found in subjects with African Lineage.•Parkinsonism may occur during the course of disease, usually in association with other movement disorders, such as chorea.•There are few reports of HDL2 patients presenting parkinsonism as the only motor...