Benchtop nuclear magnetic resonance‐based metabolomic approach for the diagnosis of bovine tuberculosis

• Published in: Transboundary and emerging diseases Vol. 69; no. 4; pp. e859 - e870
• Main Authors: Ruiz‐Cabello, Jesús, Sevilla, Iker A., Olaizola, Ekine, Bezos, Javier, Miguel‐Coello, Ana B., Muñoz‐Mendoza, Marta, Beraza, Marta, Garrido, Joseba M., Izquierdo‐García, Jose L.
• Format: Journal Article
• Language: English
• Published: Berlin John Wiley & Sons, Inc 01.07.2022
• Subjects: Animals; benchtop; bovine; bovine tuberculosis; Cattle; confidence interval; Confidence intervals; Diagnosis; diagnostic techniques; Fingerprinting; In vivo methods and tests; Magnetic resonance spectroscopy; magnetism; Metabolism; Metabolites; Metabolomics; NMR; NMR spectroscopy; Nuclear magnetic resonance; nuclear magnetic resonance spectroscopy; Paratuberculosis; Prediction models; principal component analysis; Principal components analysis; Skin tests; Spectroscopy; Spectrum analysis; Tuberculin; Tuberculosis; Vaccination

Even though enormous efforts and control strategies have been implemented, bovine tuberculosis (TB) remains a significant source of health and socioeconomic concern. The standard method used in TB eradication programs for in vivo detection is the tuberculin skin test. However, the specificity of the...