Increased hydrophobicity in Malassezia species correlates with increased proinflammatory cytokine expression in human keratinocytes

• Published in: Medical mycology (Oxford) Vol. 50; no. 8; p. 802
• Main Authors: Akaza, Narifumi, Akamatsu, Hirohiko, Takeoka, Shiori, Mizutani, Hiroshi, Nakata, Satoru, Matsunaga, Kayoko
• Format: Journal Article
• Language: English
• Published: England 01.11.2012
• Subjects: Cells, Cultured; Coculture Techniques; Cytokines - biosynthesis; Cytokines - genetics; Gene Expression Profiling; Humans; Hydrophobic and Hydrophilic Interactions; Keratinocytes - immunology; Keratinocytes - microbiology; Malassezia - chemistry; Malassezia - immunology

Malassezia cells stimulate cytokine production by keratinocytes, although this ability differs among Malassezia species for unknown reasons. The aim of this study was to clarify the factors determining the ability to induce cytokine production by human keratinocytes in response to Malassezia species...