Association of XRCC1 polymorphisms and risk of differentiated thyroid carcinoma: a case-control analysis

• Published in: Thyroid (New York, N.Y.) Vol. 19; no. 2; p. 129
• Main Authors: Ho, Tang, Li, Guojun, Lu, Jiachun, Zhao, Chong, Wei, Qingyi, Sturgis, Erich M
• Format: Journal Article
• Language: English
• Published: United States 01.02.2009
• Subjects: Case-Control Studies; DNA-Binding Proteins - genetics; Female; Genetic Predisposition to Disease; Haplotypes; Humans; Male; Middle Aged; Molecular Epidemiology; Polymorphism, Single Nucleotide; Risk; Thyroid Neoplasms - genetics; X-ray Repair Cross Complementing Protein 1

Numerous single-nucleotide polymorphisms (SNPs) of the DNA repair gene XRCC1 have been described. These SNPs have been increasingly studied in the epidemiology of various cancer types. In this study we evaluated the risk association between six common SNPs of the XRCC1 gene and differentiated thyroi...