Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice - Mehta, Zenobia B.; Fine, Nicholas; Pullen, Timothy J.; Cane, Matthew C.; Hu, Ming; Chabosseau, Pauline; Meur, Gargi; Velayos-Baeza, Antonio; Monaco, Anthony P.; Marselli, Lorella; Marchetti, Piero; Rutter, Guy A. (American journal of physiology: endocrinology and metabolism, 2016)
Keywords: Animals; Blotting, Western; Calcium - metabolism; Calcium-Binding Proteins - genetics; Call for Papers; Diabetes Mellitus, Type 2 - genetics; Female; Glucagon-Secreting Cells - pathology; Glucose Intolerance - genetics; Insulin - metabolism; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells - metabolism; Insulin-Secreting Cells - pathology; Male; Mice; Mice, Knockout; Nerve Tissue Proteins - genetics; Pancreas - pathology; Polymorphism, Single Nucleotide; Proteins - genetics; Real-Time Polymerase Chain Reaction; Sex Factors; Vesicular Transport Proteins; C2CD4A; GWAS; type 2 diabetes; β-cell; VPS13C