Cytochrome-C-oxidase expression in the subiculum and anterior thalamic nuclei of rats increases following training in an extrapolation of serial stimulus patterns task

• Published in: Physiology & behavior Vol. 296; p. 114926
• Main Authors: da Silva, Daniel Giura, Torres-Cruz, Mateus, Helou, Ammir Yacoub, Xavier, Gilberto Fernando
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2025
• Subjects: Animals; Anterior Thalamic Nuclei - enzymology; Anterior Thalamic Nuclei - metabolism; Anterodorsal thalamus; Anteroventral thalamus; Anticipatory behavior; behavior; Cytochrome C oxidase; Electron Transport Complex IV - metabolism; Generator of predictions system; Helianthus annuus; Male; males; physiology; Rats; Rats, Wistar; Septohippocampal system; Serial Learning - physiology; thalamus; C; SubD; GPS; L; M; SS1; AUD; SubV; Cytochrome C oxidase; SS2; VS2; VS1; MC; Generator of predictions system; ML; Septohippocampal system; Anterodorsal thalamus; AD; NMC; Anteroventral thalamus; NML; COX; Anticipatory behavior; ATN; HF; AVT; NM

•Rats extrapolate relying on serial stimulus patterns.•The subiculum and anterior thalamus contribute to extrapolation.•COX expression increases along with training for extrapolation.•Serial stimulus pattern training engages the subiculum and anterior thalamus. The brain continuously monitors the en...