Cutaneous Metastases in Patients with Rectal Cancer : A Report of Six Cases

Cutaneous metastases from rectal cancer are rare manifestations of disseminated disease and uniformly represent dismal survival. A retrospective review of six patients with rectal cancer metastatic to the dermis was performed. The diagnosis of rectal cancer was made concurrently with the diagnosis o...

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Published inThe American surgeon Vol. 74; no. 2; pp. 138 - 140
Main Authors GAZONI, Leo M, HEDRICK, Traci L, SMITH, Philip W, FRIEL, Charles M, SWENSON, Brian R, ADAMS, Joshua D, LISLE, Turner C, FOLEY, Eugene F, LEDESMA, Elihu J
Format Journal Article
LanguageEnglish
Published Atlanta, GA Southeastern Surgical Congress 01.02.2008
SAGE PUBLICATIONS, INC
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Abstract Cutaneous metastases from rectal cancer are rare manifestations of disseminated disease and uniformly represent dismal survival. A retrospective review of six patients with rectal cancer metastatic to the dermis was performed. The diagnosis of rectal cancer was made concurrently with the diagnosis of the dermal metastases in all six patients. A 100 per cent histopathologic concordance existed between the tissue of the dermal metastases and primary rectal tumor. The progression of systemic metastatic disease was the cause of death in 83.3 per cent of patients (5/6). No patient survived more than 7 months from the time of diagnosis. Recognition of suspicious skin lesions as possible harbingers of undiagnosed visceral malignancy is important in managing patients both with and without a history of previous cancer.
AbstractList Cutaneous metastases from rectal cancer are rare manifestations of disseminated disease and uniformly represent dismal survival. A retrospective review of six patients with rectal cancer metastatic to the dermis was performed. The diagnosis of rectal cancer was made concurrently with the diagnosis of the dermal metastases in all six patients. A 100 per cent histopathologic concordance existed between the tissue of the dermal metastases and primary rectal tumor. The progression of systemic metastatic disease was the cause of death in 83.3 per cent of patients (5/6). No patient survived more than 7 months from the time of diagnosis. Recognition of suspicious skin lesions as possible harbingers of undiagnosed visceral malignancy is important in managing patients both with and without a history of previous cancer. [PUBLICATION ABSTRACT]
Cutaneous metastases from rectal cancer are rare manifestations of disseminated disease and uniformly represent dismal survival. A retrospective review of six patients with rectal cancer metastatic to the dermis was performed. The diagnosis of rectal cancer was made concurrently with the diagnosis of the dermal metastases in all six patients. A 100 per cent histopathologic concordance existed between the tissue of the dermal metastases and primary rectal tumor. The progression of systemic metastatic disease was the cause of death in 83.3 per cent of patients (5/6). No patient survived more than 7 months from the time of diagnosis. Recognition of suspicious skin lesions as possible harbingers of undiagnosed visceral malignancy is important in managing patients both with and without a history of previous cancer.
Author FOLEY, Eugene F
SWENSON, Brian R
FRIEL, Charles M
SMITH, Philip W
LEDESMA, Elihu J
GAZONI, Leo M
ADAMS, Joshua D
LISLE, Turner C
HEDRICK, Traci L
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  surname: HEDRICK
  fullname: HEDRICK, Traci L
  organization: Department of Surgery, University of Virginia, Charlottesville, Virginia, United States
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  givenname: Philip W
  surname: SMITH
  fullname: SMITH, Philip W
  organization: Department of Surgery, University of Virginia, Charlottesville, Virginia, United States
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  givenname: Charles M
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  fullname: FRIEL, Charles M
  organization: Department of Surgery, University of Virginia, Charlottesville, Virginia, United States
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  givenname: Brian R
  surname: SWENSON
  fullname: SWENSON, Brian R
  organization: Department of Surgery, University of Virginia, Charlottesville, Virginia, United States
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  surname: ADAMS
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  surname: LISLE
  fullname: LISLE, Turner C
  organization: Department of Surgery, University of Virginia, Charlottesville, Virginia, United States
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  givenname: Elihu J
  surname: LEDESMA
  fullname: LEDESMA, Elihu J
  organization: Department of Surgery, University of Virginia, Charlottesville, Virginia, United States
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Issue 2
Keywords Human
Rectal disease
Report
Patient
Malignant tumor
Rectum cancer
Metastasis
Medicine
Treatment
Surgery
Digestive diseases
Intestinal disease
Skin
Anorectal disease
Cancer
Language English
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bibr13-000313480807400210
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StartPage 138
SubjectTerms Abdomen
Adenocarcinoma - secondary
Aged
Biological and medical sciences
Chemotherapy
Colorectal cancer
Female
Gastroenterology. Liver. Pancreas. Abdomen
General aspects
Heart attacks
Humans
Male
Medical sciences
Middle Aged
Patients
Rectal Neoplasms - pathology
Retrospective Studies
Skin Neoplasms - secondary
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Tumors
Title Cutaneous Metastases in Patients with Rectal Cancer : A Report of Six Cases
URI https://www.ncbi.nlm.nih.gov/pubmed/18306865
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