Minute ventilation/carbon dioxide production in patients with dysfunctional breathing

Dysfunctional breathing refers to a multi-dimensional condition that is characterised by pathological changes in an individual's breathing. These changes lead to a feeling of breathlessness and include alterations in the biomechanical, psychological and physiological aspects of breathing. This...

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Published inEuropean respiratory review Vol. 30; no. 160; p. 200182
Main Authors Watson, Matthew, Ionescu, Maria Florina, Sylvester, Karl, Fuld, Jonathan
Format Journal Article
LanguageEnglish
Published England European Respiratory Society 30.06.2021
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Abstract Dysfunctional breathing refers to a multi-dimensional condition that is characterised by pathological changes in an individual's breathing. These changes lead to a feeling of breathlessness and include alterations in the biomechanical, psychological and physiological aspects of breathing. This makes dysfunctional breathing a hard condition to diagnose, given the diversity of aspects that contribute to the feeling of breathlessness. The disorder can debilitate individuals without any health problems, but may also be present in those with underlying cardiopulmonary co-morbidities. The ventilatory equivalent for CO ( ) is a physiological parameter that can be measured using cardiopulmonary exercise testing. This review will explore how this single measurement can be used to aid the diagnosis of dysfunctional breathing. A background discussion about dysfunctional breathing will allow readers to comprehend its multidimensional aspects. This will then allow readers to understand how can be used in the wider diagnosis of dysfunctional breathing. Whilst cannot be used as a singular parameter in the diagnosis of dysfunctional breathing, this review supports its use within a broader algorithm to detect physiological abnormalities in patients with dysfunctional breathing. This will allow for more individuals to be accurately diagnosed and appropriately managed.
AbstractList Dysfunctional breathing refers to a multi-dimensional condition that is characterised by pathological changes in an individual's breathing. These changes lead to a feeling of breathlessness and include alterations in the biomechanical, psychological and physiological aspects of breathing. This makes dysfunctional breathing a hard condition to diagnose, given the diversity of aspects that contribute to the feeling of breathlessness. The disorder can debilitate individuals without any health problems, but may also be present in those with underlying cardiopulmonary co-morbidities. The ventilatory equivalent for CO 2 ( V eqCO 2 ) is a physiological parameter that can be measured using cardiopulmonary exercise testing. This review will explore how this single measurement can be used to aid the diagnosis of dysfunctional breathing. A background discussion about dysfunctional breathing will allow readers to comprehend its multidimensional aspects. This will then allow readers to understand how V eqCO 2 can be used in the wider diagnosis of dysfunctional breathing. Whilst V eqCO 2 cannot be used as a singular parameter in the diagnosis of dysfunctional breathing, this review supports its use within a broader algorithm to detect physiological abnormalities in patients with dysfunctional breathing. This will allow for more individuals to be accurately diagnosed and appropriately managed.
Dysfunctional breathing refers to a multi-dimensional condition that is characterised by pathological changes in an individual's breathing. These changes lead to a feeling of breathlessness and include alterations in the biomechanical, psychological and physiological aspects of breathing. This makes dysfunctional breathing a hard condition to diagnose, given the diversity of aspects that contribute to the feeling of breathlessness. The disorder can debilitate individuals without any health problems, but may also be present in those with underlying cardiopulmonary co-morbidities. The ventilatory equivalent for CO 2 ( V eqCO 2 ) is a physiological parameter that can be measured using cardiopulmonary exercise testing. This review will explore how this single measurement can be used to aid the diagnosis of dysfunctional breathing. A background discussion about dysfunctional breathing will allow readers to comprehend its multidimensional aspects. This will then allow readers to understand how V eqCO 2 can be used in the wider diagnosis of dysfunctional breathing. Whilst V eqCO 2 cannot be used as a singular parameter in the diagnosis of dysfunctional breathing, this review supports its use within a broader algorithm to detect physiological abnormalities in patients with dysfunctional breathing. This will allow for more individuals to be accurately diagnosed and appropriately managed. Ventilatory equivalent for CO 2 can provide information to aid the diagnosis of dysfunctional breathing, particularly hyperventilation syndrome https://bit.ly/2OwTMqY
Dysfunctional breathing refers to a multi-dimensional condition that is characterised by pathological changes in an individual's breathing. These changes lead to a feeling of breathlessness and include alterations in the biomechanical, psychological and physiological aspects of breathing. This makes dysfunctional breathing a hard condition to diagnose, given the diversity of aspects that contribute to the feeling of breathlessness. The disorder can debilitate individuals without any health problems, but may also be present in those with underlying cardiopulmonary co-morbidities. The ventilatory equivalent for CO ( ) is a physiological parameter that can be measured using cardiopulmonary exercise testing. This review will explore how this single measurement can be used to aid the diagnosis of dysfunctional breathing. A background discussion about dysfunctional breathing will allow readers to comprehend its multidimensional aspects. This will then allow readers to understand how can be used in the wider diagnosis of dysfunctional breathing. Whilst cannot be used as a singular parameter in the diagnosis of dysfunctional breathing, this review supports its use within a broader algorithm to detect physiological abnormalities in patients with dysfunctional breathing. This will allow for more individuals to be accurately diagnosed and appropriately managed.
Author Ionescu, Maria Florina
Sylvester, Karl
Watson, Matthew
Fuld, Jonathan
AuthorAffiliation 3 Respiratory Physiology, Papworth Hospitals NHS Foundation Trust, Cambridge, UK
2 Lung Function, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
4 Dept of Respiratory Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
1 School of Clinical Medicine, University of Cambridge, Cambridge, UK
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  surname: Ionescu
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  organization: School of Clinical Medicine, University of Cambridge, Cambridge, UK
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  surname: Sylvester
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Cites_doi 10.1007/s10484-008-9052-3
10.1183/16000617.0088-2015
10.1378/chest.130.6.1723
10.1016/j.rmed.2011.03.006
10.1136/thoraxjnl-2011-201054c.189
10.1371/journal.pone.0215997
10.1378/chest.112.4.1091
10.1016/j.prrv.2014.10.001
10.1183/20734735.007216
10.1007/s10484-015-9316-7
10.1016/0022-3999(85)90042-X
10.1159/000196215
10.1016/j.rmed.2013.10.024
10.1016/0735-1097(92)90244-H
10.1183/23120541.00001-2015
10.1016/j.ijosm.2009.04.002
10.1183/09031936.04.00111904
10.1183/09031936.99.14613149
10.1177/0145445503256318
10.1186/1471-2466-12-23
10.1164/rccm.2202033
10.1016/j.cardfail.2009.05.012
10.1513/AnnalsATS.201612-997FR
10.1016/j.pcrj.2004.10.007
10.1590/1806-3713/e20170347
10.1080/02770900802252093
10.1111/crj.12016
10.1016/j.jbmt.2010.06.004
10.1111/resp.13173
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References 2024102403532058000_30.160.200182.14
2024102403532058000_30.160.200182.36
2024102403532058000_30.160.200182.15
2024102403532058000_30.160.200182.35
2024102403532058000_30.160.200182.10
2024102403532058000_30.160.200182.32
2024102403532058000_30.160.200182.11
2024102403532058000_30.160.200182.33
2024102403532058000_30.160.200182.30
Harf (2024102403532058000_30.160.200182.27) 1978; 44
Mezzani (2024102403532058000_30.160.200182.26) 2017; 14
2024102403532058000_30.160.200182.16
Thing (2024102403532058000_30.160.200182.24) 2011; 66
2024102403532058000_30.160.200182.17
Roberts (2024102403532058000_30.160.200182.23) 2017; 50
Kinnula (2024102403532058000_30.160.200182.28) 1993; 60
Levai (2024102403532058000_30.160.200182.18) 2016; 48
Griffiths (2024102403532058000_30.160.200182.21) 2014; 44
2024102403532058000_30.160.200182.2
Berend (2024102403532058000_30.160.200182.31) 2018; 379
2024102403532058000_30.160.200182.7
2024102403532058000_30.160.200182.25
2024102403532058000_30.160.200182.9
2024102403532058000_30.160.200182.3
2024102403532058000_30.160.200182.4
2024102403532058000_30.160.200182.5
Degani Costa (2024102403532058000_30.160.200182.20) 2016; 48
2024102403532058000_30.160.200182.29
Johansen (2024102403532058000_30.160.200182.34) 2013; 7
Todd (2024102403532058000_30.160.200182.12) 2018; 23
Mitchell (2024102403532058000_30.160.200182.13) 2015; 41
Brat (2024102403532058000_30.160.200182.19) 2019; 14
Chenivesse (2024102403532058000_30.160.200182.1) 2014; 108
Vidotto (2024102403532058000_30.160.200182.6) 2019; 45
Courtney (2024102403532058000_30.160.200182.8) 2009; 12
Jayadev (2024102403532058000_30.160.200182.22) 2017; 50
References_xml – ident: 2024102403532058000_30.160.200182.17
  doi: 10.1007/s10484-008-9052-3
– ident: 2024102403532058000_30.160.200182.4
  doi: 10.1183/16000617.0088-2015
– ident: 2024102403532058000_30.160.200182.10
  doi: 10.1378/chest.130.6.1723
– ident: 2024102403532058000_30.160.200182.2
  doi: 10.1016/j.rmed.2011.03.006
– volume: 50
  start-page: PA4538
  issue: Suppl. 61
  year: 2017
  ident: 2024102403532058000_30.160.200182.22
  article-title: The role of cardiopulmonary exercise testing in the investigation of complex unexplained breathlessness
  publication-title: Eur Respir J
  contributor:
    fullname: Jayadev
– volume: 66
  start-page: A144 LP
  issue: Suppl. 4
  year: 2011
  ident: 2024102403532058000_30.160.200182.24
  article-title: P189 Evaluation of the role of cardio-pulmonary exercise testing in the diagnosis of unexplained breathlessness
  publication-title: Thorax
  doi: 10.1136/thoraxjnl-2011-201054c.189
  contributor:
    fullname: Thing
– volume: 14
  start-page: e0215997
  year: 2019
  ident: 2024102403532058000_30.160.200182.19
  article-title: Cardiopulmonary exercise testing for identification of patients with hyperventilation syndrome
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0215997
  contributor:
    fullname: Brat
– ident: 2024102403532058000_30.160.200182.25
  doi: 10.1378/chest.112.4.1091
– volume: 379
  start-page: 496
  year: 2018
  ident: 2024102403532058000_30.160.200182.31
  article-title: Diagnostic use of base excess in acid-base disorders
  publication-title: N Engl J Med
  contributor:
    fullname: Berend
– ident: 2024102403532058000_30.160.200182.5
  doi: 10.1016/j.prrv.2014.10.001
– ident: 2024102403532058000_30.160.200182.9
  doi: 10.1183/20734735.007216
– volume: 41
  start-page: 111
  year: 2015
  ident: 2024102403532058000_30.160.200182.13
  article-title: Reliability and Determinants of Self-Evaluation of Breathing Questionnaire (SEBQ) Score: a symptoms-based measure of dysfunctional breathing
  publication-title: Appl Psychophysiol Biofeedback
  doi: 10.1007/s10484-015-9316-7
  contributor:
    fullname: Mitchell
– volume: 50
  start-page: PA4537
  issue: Suppl. 61
  year: 2017
  ident: 2024102403532058000_30.160.200182.23
  article-title: Cardiopulmonary excercise testing in the diagnosis of chronic unexplained dyspnoea
  publication-title: Eur Respir J
  contributor:
    fullname: Roberts
– volume: 48
  start-page: OA2016
  issue: Suppl. 60
  year: 2016
  ident: 2024102403532058000_30.160.200182.20
  article-title: The role of cardiopulmonary exercise testing in the diagnosis of psychogenic dyspnoea
  publication-title: Eur Respir J
  contributor:
    fullname: Degani Costa
– ident: 2024102403532058000_30.160.200182.14
  doi: 10.1016/0022-3999(85)90042-X
– volume: 44
  start-page: P4886
  issue: Suppl. 58
  year: 2014
  ident: 2024102403532058000_30.160.200182.21
  article-title: Cardiopulmonary exercise testing (CPET) in patients with unexplained dyspnoea
  publication-title: Eur Respir J
  contributor:
    fullname: Griffiths
– volume: 60
  start-page: 273
  year: 1993
  ident: 2024102403532058000_30.160.200182.28
  article-title: Elevated ventilatory equivalents during exercise in patients with hyperventilation syndrome
  publication-title: Respiration
  doi: 10.1159/000196215
  contributor:
    fullname: Kinnula
– volume: 108
  start-page: 517
  year: 2014
  ident: 2024102403532058000_30.160.200182.1
  article-title: Severely impaired health-related quality of life in chronic hyperventilation patients: exploratory data
  publication-title: Respir Med
  doi: 10.1016/j.rmed.2013.10.024
  contributor:
    fullname: Chenivesse
– ident: 2024102403532058000_30.160.200182.33
  doi: 10.1016/0735-1097(92)90244-H
– ident: 2024102403532058000_30.160.200182.15
  doi: 10.1183/23120541.00001-2015
– volume: 12
  start-page: 78
  year: 2009
  ident: 2024102403532058000_30.160.200182.8
  article-title: The functions of breathing and its dysfunctions and their relationship to breathing therapy
  publication-title: Int J Osteopath Med
  doi: 10.1016/j.ijosm.2009.04.002
  contributor:
    fullname: Courtney
– ident: 2024102403532058000_30.160.200182.32
  doi: 10.1183/09031936.04.00111904
– ident: 2024102403532058000_30.160.200182.30
  doi: 10.1183/09031936.99.14613149
– volume: 44
  start-page: 115
  year: 1978
  ident: 2024102403532058000_30.160.200182.27
  article-title: Regional distribution of VA/Q in man at rest and with exercise measured with krypton-81 m
  publication-title: J Appl Physiol Respir Environ Exerc Physiol
  contributor:
    fullname: Harf
– ident: 2024102403532058000_30.160.200182.29
  doi: 10.1177/0145445503256318
– ident: 2024102403532058000_30.160.200182.36
  doi: 10.1186/1471-2466-12-23
– ident: 2024102403532058000_30.160.200182.7
  doi: 10.1164/rccm.2202033
– ident: 2024102403532058000_30.160.200182.35
  doi: 10.1016/j.cardfail.2009.05.012
– volume: 14
  start-page: S3
  issue: Suppl. 1
  year: 2017
  ident: 2024102403532058000_30.160.200182.26
  article-title: Cardiopulmonary Exercise Testing: Basics of Methodology and Measurements
  publication-title: Ann Am Thorac Soc
  doi: 10.1513/AnnalsATS.201612-997FR
  contributor:
    fullname: Mezzani
– ident: 2024102403532058000_30.160.200182.3
  doi: 10.1016/j.pcrj.2004.10.007
– volume: 45
  start-page: e20170347
  year: 2019
  ident: 2024102403532058000_30.160.200182.6
  article-title: Dysfunctional breathing: what do we know?
  publication-title: J Bras Pneumol
  doi: 10.1590/1806-3713/e20170347
  contributor:
    fullname: Vidotto
– ident: 2024102403532058000_30.160.200182.16
  doi: 10.1080/02770900802252093
– volume: 7
  start-page: 359
  year: 2013
  ident: 2024102403532058000_30.160.200182.34
  article-title: Normalizing CO2 in chronic hyperventilation by means of a novel breathing mask: a pilot study
  publication-title: Clin Respir J
  doi: 10.1111/crj.12016
  contributor:
    fullname: Johansen
– ident: 2024102403532058000_30.160.200182.11
  doi: 10.1016/j.jbmt.2010.06.004
– volume: 23
  start-page: 284
  year: 2018
  ident: 2024102403532058000_30.160.200182.12
  article-title: Novel assessment tool to detect breathing pattern disorder in patients with refractory asthma
  publication-title: Respirology
  doi: 10.1111/resp.13173
  contributor:
    fullname: Todd
– volume: 48
  start-page: PA2248
  issue: Suppl. 60
  year: 2016
  ident: 2024102403532058000_30.160.200182.18
  article-title: Optoelectronic plethysmography (OEP) in the assessment of dysfunctional breathing (DB) in athletes
  publication-title: Eur Respir J
  contributor:
    fullname: Levai
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Snippet Dysfunctional breathing refers to a multi-dimensional condition that is characterised by pathological changes in an individual's breathing. These changes lead...
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Title Minute ventilation/carbon dioxide production in patients with dysfunctional breathing
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