Multiple chronic conditions and life expectancy: a life table analysis

The number of people living with multiple chronic conditions is increasing, but we know little about the impact of multimorbidity on life expectancy. We analyze life expectancy in Medicare beneficiaries by number of chronic conditions. A retrospective cohort study using single-decrement period life...

Full description

Saved in:
Bibliographic Details
Published inMedical care Vol. 52; no. 8; p. 688
Main Authors DuGoff, Eva H, Canudas-Romo, Vladimir, Buttorff, Christine, Leff, Bruce, Anderson, Gerard F
Format Journal Article
LanguageEnglish
Published United States 01.08.2014
Subjects
Online AccessGet more information
ISSN1537-1948
DOI10.1097/MLR.0000000000000166

Cover

Loading…
Abstract The number of people living with multiple chronic conditions is increasing, but we know little about the impact of multimorbidity on life expectancy. We analyze life expectancy in Medicare beneficiaries by number of chronic conditions. A retrospective cohort study using single-decrement period life tables. Medicare fee-for-service beneficiaries (N=1,372,272) aged 67 and older as of January 1, 2008. Our primary outcome measure is life expectancy. We categorize study subjects by sex, race, selected chronic conditions (heart disease, cancer, chronic obstructive pulmonary disease, stroke, and Alzheimer disease), and number of comorbid conditions. Comorbidity was measured as a count of conditions collected by Chronic Conditions Warehouse and the Charlson Comorbidity Index. Life expectancy decreases with each additional chronic condition. A 67-year-old individual with no chronic conditions will live on average 22.6 additional years. A 67-year-old individual with 5 chronic conditions and ≥10 chronic conditions will live 7.7 fewer years and 17.6 fewer years, respectively. The average marginal decline in life expectancy is 1.8 years with each additional chronic condition-ranging from 0.4 fewer years with the first condition to 2.6 fewer years with the sixth condition. These results are consistent by sex and race. We observe differences in life expectancy by selected conditions at 67, but these differences diminish with age and increasing numbers of comorbid conditions. Social Security and Medicare actuaries should account for the growing number of beneficiaries with multiple chronic conditions when determining population projections and trust fund solvency.
AbstractList The number of people living with multiple chronic conditions is increasing, but we know little about the impact of multimorbidity on life expectancy. We analyze life expectancy in Medicare beneficiaries by number of chronic conditions. A retrospective cohort study using single-decrement period life tables. Medicare fee-for-service beneficiaries (N=1,372,272) aged 67 and older as of January 1, 2008. Our primary outcome measure is life expectancy. We categorize study subjects by sex, race, selected chronic conditions (heart disease, cancer, chronic obstructive pulmonary disease, stroke, and Alzheimer disease), and number of comorbid conditions. Comorbidity was measured as a count of conditions collected by Chronic Conditions Warehouse and the Charlson Comorbidity Index. Life expectancy decreases with each additional chronic condition. A 67-year-old individual with no chronic conditions will live on average 22.6 additional years. A 67-year-old individual with 5 chronic conditions and ≥10 chronic conditions will live 7.7 fewer years and 17.6 fewer years, respectively. The average marginal decline in life expectancy is 1.8 years with each additional chronic condition-ranging from 0.4 fewer years with the first condition to 2.6 fewer years with the sixth condition. These results are consistent by sex and race. We observe differences in life expectancy by selected conditions at 67, but these differences diminish with age and increasing numbers of comorbid conditions. Social Security and Medicare actuaries should account for the growing number of beneficiaries with multiple chronic conditions when determining population projections and trust fund solvency.
Author DuGoff, Eva H
Buttorff, Christine
Leff, Bruce
Anderson, Gerard F
Canudas-Romo, Vladimir
Author_xml – sequence: 1
  givenname: Eva H
  surname: DuGoff
  fullname: DuGoff, Eva H
  organization: Johns Hopkins University Bloomberg School of Public Health, Baltimore MD †University of Southern Denmark, Max-Planck Odense Center, Denmark ‡Johns Hopkins University School of Medicine §Johns Hopkins University School of Nursing, Baltimore, MD
– sequence: 2
  givenname: Vladimir
  surname: Canudas-Romo
  fullname: Canudas-Romo, Vladimir
– sequence: 3
  givenname: Christine
  surname: Buttorff
  fullname: Buttorff, Christine
– sequence: 4
  givenname: Bruce
  surname: Leff
  fullname: Leff, Bruce
– sequence: 5
  givenname: Gerard F
  surname: Anderson
  fullname: Anderson, Gerard F
BackLink https://www.ncbi.nlm.nih.gov/pubmed/25023914$$D View this record in MEDLINE/PubMed
BookMark eNpNT11LxDAQDKJ4H_oPRPIHepek3TT1TQ5PhR4Hos_HNt1gpJeWpgf231s4BedlhoGZ3Vmwy9AGYuxOipUURb7elW8r8R9S6ws2l5DmiSwyM2OLGL8mO09BXbOZAqHSQmZztt2dmsF3DXH72bfBW27bUPvBtyFyDDVvvCNO3x3ZAYMdHzierQGrKYQBmzH6eMOuHDaRbn95yT62T--bl6TcP79uHsvEZtPFhMDmJiWppTAOCdT0oazIOkyhkJUxNUItJq0pE0BSaNAGjMsLUAAO1ZLdn3u7U3Wk-tD1_oj9ePgbpH4A7mxM5Q
CitedBy_id crossref_primary_10_1097_XCS_0000000000001040
crossref_primary_10_1007_s43546_024_00640_7
crossref_primary_10_26442_00403660_2024_09_202848
crossref_primary_10_1007_s11606_020_06119_z
crossref_primary_10_1001_jamanetworkopen_2021_12062
crossref_primary_10_1016_j_drudis_2020_06_016
crossref_primary_10_1016_j_ypmed_2020_106225
crossref_primary_10_1097_NJH_0000000000000215
crossref_primary_10_1111_jgs_17468
crossref_primary_10_21518_2079_701X_2020_11_26_31
crossref_primary_10_1111_jgs_14868
crossref_primary_10_5014_ajot_2022_76S3003
crossref_primary_10_1093_tbm_ibx084
crossref_primary_10_3402_pba_v6_33276
crossref_primary_10_1007_s11357_020_00261_6
crossref_primary_10_1590_1413_812320202510_34492018
crossref_primary_10_1016_j_ypmed_2020_106330
crossref_primary_10_1080_00981389_2021_1908482
crossref_primary_10_1016_j_pec_2023_108078
crossref_primary_10_1016_j_tpb_2023_05_001
crossref_primary_10_21560_spcd_vi_1150176
crossref_primary_10_1111_jgs_17113
crossref_primary_10_1097_MLR_0000000000001566
crossref_primary_10_1001_jamanetworkopen_2022_20162
crossref_primary_10_1159_000502757
crossref_primary_10_1177_09636897211046559
crossref_primary_10_1371_journal_pone_0230674
crossref_primary_10_1111_jgs_16537
crossref_primary_10_1186_s12877_017_0434_3
crossref_primary_10_1016_j_jamda_2015_03_013
crossref_primary_10_1111_jgs_16539
crossref_primary_10_3390_antiox8020044
crossref_primary_10_1001_jamainternmed_2020_6084
crossref_primary_10_1093_gerona_glac087
crossref_primary_10_1007_s41999_022_00717_2
crossref_primary_10_2196_28723
crossref_primary_10_3390_geriatrics4020039
crossref_primary_10_1016_j_aprim_2024_103112
crossref_primary_10_1001_jamanetworkopen_2019_15245
crossref_primary_10_4251_wjgo_v14_i6_1086
crossref_primary_10_1080_01488376_2025_2451938
crossref_primary_10_5888_pcd16_180641
crossref_primary_10_1371_journal_pone_0245193
crossref_primary_10_1016_j_archger_2020_104135
crossref_primary_10_1080_02813432_2019_1608056
crossref_primary_10_1017_S146342361900094X
crossref_primary_10_1590_1413_81232018239_22532016
crossref_primary_10_3390_pharmacy10010014
crossref_primary_10_1093_gerona_glaa094
crossref_primary_10_1177_2235042X20950598
crossref_primary_10_1007_s10549_022_06541_3
crossref_primary_10_1093_gerona_glz147
crossref_primary_10_1177_0898264320983663
crossref_primary_10_15829_1728_8800_2019_1_5_66
crossref_primary_10_1089_pop_2019_0231
crossref_primary_10_1177_2333721419856436
crossref_primary_10_1097_PHH_0000000000001352
crossref_primary_10_1111_jocn_17524
crossref_primary_10_1016_j_archger_2023_105219
crossref_primary_10_1016_j_jfma_2021_05_029
crossref_primary_10_18865_1704
crossref_primary_10_1245_s10434_015_4902_8
crossref_primary_10_1111_acel_12737
crossref_primary_10_1038_s41598_022_19244_y
crossref_primary_10_1177_26335565211032880
crossref_primary_10_1038_s41598_022_15764_9
crossref_primary_10_1080_10570314_2022_2135385
crossref_primary_10_1007_s00394_019_02131_0
crossref_primary_10_18261_issn_2387_5984_2018_02_03
crossref_primary_10_1097_CEJ_0000000000000739
crossref_primary_10_1097_MLR_0000000000000383
crossref_primary_10_1007_s00120_018_0735_y
crossref_primary_10_1371_journal_pone_0236861
crossref_primary_10_1016_j_ctarc_2022_100619
crossref_primary_10_1186_s40814_019_0403_z
crossref_primary_10_1093_geronb_gbx118
crossref_primary_10_1177_26335565221122025
crossref_primary_10_1097_JAC_0000000000000342
crossref_primary_10_20996_1819_6446_2020_02_11
crossref_primary_10_1002_cam4_3274
crossref_primary_10_1093_heapro_daad176
crossref_primary_10_1016_j_canep_2018_08_003
crossref_primary_10_20514_2226_6704_2021_11_1_34_42
crossref_primary_10_29001_2073_8552_2020_35_1_93_99
crossref_primary_10_1016_j_jval_2019_08_002
crossref_primary_10_1186_s12885_022_10418_5
crossref_primary_10_1007_s11205_021_02699_3
crossref_primary_10_1016_j_jagp_2020_05_014
crossref_primary_10_1123_japa_2019_0086
crossref_primary_10_1111_jgs_14201
crossref_primary_10_1186_s12916_019_1305_x
crossref_primary_10_1590_1981_22562019022_180154
crossref_primary_10_1016_j_cger_2016_01_004
crossref_primary_10_14336_AD_2019_0616
crossref_primary_10_24201_edu_v38i1_2108
crossref_primary_10_1007_s00520_022_07247_4
crossref_primary_10_1186_s12889_022_12722_y
crossref_primary_10_1371_journal_pgen_1005728
crossref_primary_10_3389_fmed_2022_831544
crossref_primary_10_1089_lgbt_2023_0139
crossref_primary_10_2196_36787
crossref_primary_10_1016_j_archger_2019_103909
crossref_primary_10_1016_j_ejca_2025_115303
crossref_primary_10_1016_j_nepr_2021_102990
crossref_primary_10_1111_codi_17269
crossref_primary_10_18705_1607_419X_2020_26_1_15_26
crossref_primary_10_1186_s12911_022_01766_0
crossref_primary_10_33667_2078_5631_2021_11_12_19
crossref_primary_10_1177_2235042X18804063
crossref_primary_10_3389_fpubh_2021_760792
crossref_primary_10_3390_computation12080154
crossref_primary_10_1007_s12325_023_02485_2
crossref_primary_10_1016_j_abb_2022_109469
crossref_primary_10_37586_2686_8636_1_2021_53_59
crossref_primary_10_1007_s40266_022_00973_8
crossref_primary_10_1177_26335565231157626
crossref_primary_10_1007_s11356_023_28330_1
crossref_primary_10_15829_1560_4071_2021_3940
crossref_primary_10_1590_s1679_49742021000300015
crossref_primary_10_1007_s44155_022_00028_8
crossref_primary_10_1007_s11605_020_04590_x
crossref_primary_10_3390_nu16213669
crossref_primary_10_1002_rcs_2157
crossref_primary_10_1038_s41467_020_16540_x
crossref_primary_10_1259_bjr_20150111
crossref_primary_10_1186_s12875_020_01197_8
crossref_primary_10_1371_journal_pone_0190683
crossref_primary_10_1590_1413_812320202510_35632018
crossref_primary_10_5888_pcd12_140478
crossref_primary_10_1159_000500119
crossref_primary_10_1093_gerona_glac221
crossref_primary_10_1097_DCC_0000000000000269
crossref_primary_10_20996_1819_6446_2020_11_07
crossref_primary_10_15446_rsap_v21n5_77775
crossref_primary_10_1111_jgs_14539
crossref_primary_10_1016_j_ejim_2023_01_011
ContentType Journal Article
DBID CGR
CUY
CVF
ECM
EIF
NPM
DOI 10.1097/MLR.0000000000000166
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
DatabaseTitleList MEDLINE
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod no_fulltext_linktorsrc
Discipline Medicine
Public Health
EISSN 1537-1948
ExternalDocumentID 25023914
Genre Research Support, Non-U.S. Gov't
Journal Article
GeographicLocations United States
GeographicLocations_xml – name: United States
GrantInformation_xml – fundername: AHRQ HHS
  grantid: T32 HS000029
GroupedDBID ---
-~X
.-D
..I
.3C
.GJ
.Z2
01R
0R~
1J1
3R3
40H
4Q1
4Q2
4Q3
53G
5GY
5VS
71W
77Y
7O~
8L-
AAAAV
AAAXR
AAGIX
AAHPQ
AAIQE
AAKYL
AAMOA
AAMTA
AAQKA
AAQQT
AARTV
AASCR
AASOK
AAWTL
AAWTO
AAXQO
AAYEP
ABASU
ABBHK
ABBUW
ABDIG
ABIVO
ABJNI
ABPPZ
ABQDR
ABVCZ
ABXSQ
ABXVJ
ABZAD
ACCJW
ACDDN
ACDIW
ACEWG
ACGFO
ACGFS
ACHQT
ACIJW
ACILI
ACLDA
ACLED
ACNWC
ACWDW
ACWRI
ACXJB
ACXNZ
ADFPA
ADGGA
ADHPY
ADNKB
ADULT
AE3
AE6
AEETU
AELLO
AENEX
AEUPB
AFDTB
AFRAH
AFUWQ
AGINI
AHMBA
AHOMT
AHQNM
AHRYX
AHVBC
AIJEX
AINUH
AJCLO
AJIOK
AJNWD
AJNYG
AJRGT
AJZMW
AKBRZ
AKCTQ
AKULP
ALKUP
ALMA_UNASSIGNED_HOLDINGS
ALMTX
AMJPA
AMKUR
AMNEI
AOHHW
AWKKM
BHOJU
BOYCO
BQLVK
BS7
BYPQX
C45
CGR
CS3
CUY
CVF
DIWNM
DU5
DUNZO
E.X
EBS
ECM
EEVPB
EIF
EJD
ERAAH
EX3
F2K
F2L
F2M
F2N
F5P
FCALG
FL-
FW0
GIFXF
GNXGY
GQDEL
H0~
HGD
HLJTE
HVGLF
HZ~
H~9
IH2
IKREB
IKYAY
IN~
IPNFZ
IPSME
JAA
JAAYA
JBMMH
JBZCM
JENOY
JF9
JG8
JHFFW
JK3
JK8
JKQEH
JLEZI
JLXEF
JPL
JSODD
JST
K8S
KD2
KMI
L-C
L7B
N4W
N9A
NPM
N~7
N~B
N~M
O9-
OAG
OAH
OCUKA
ODA
ODZKP
OJAPA
OL1
OLG
OLH
OLL
OLU
OLV
OLW
OLY
OLZ
OPUJH
OPX
ORVUJ
OUVQU
OVD
OVDNE
OVIDH
OVLEI
OWBYB
OWU
OWV
OWW
OWX
OWY
OWZ
OXXIT
P-K
P-O
P2P
PKN
PQQKQ
QZG
R58
RIG
RLZ
S4R
S4S
SA0
T8P
TEORI
TN5
TSPGW
V2I
VQP
VVN
W3M
WH7
WOQ
WOW
X3V
X3W
XFW
XXN
XYM
YCJ
YFH
YHZ
YOC
ZFV
ZGI
ZXP
ZY1
ZZMQN
ID FETCH-LOGICAL-c4023-e5c783e16108fae521531becfa3591b88da5d03596e405e10656858f795255fa2
IngestDate Wed Feb 19 02:15:36 EST 2025
IsPeerReviewed true
IsScholarly true
Issue 8
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c4023-e5c783e16108fae521531becfa3591b88da5d03596e405e10656858f795255fa2
PMID 25023914
ParticipantIDs pubmed_primary_25023914
PublicationCentury 2000
PublicationDate 2014-August
PublicationDateYYYYMMDD 2014-08-01
PublicationDate_xml – month: 08
  year: 2014
  text: 2014-August
PublicationDecade 2010
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Medical care
PublicationTitleAlternate Med Care
PublicationYear 2014
SSID ssj0017352
Score 2.498416
Snippet The number of people living with multiple chronic conditions is increasing, but we know little about the impact of multimorbidity on life expectancy. We...
SourceID pubmed
SourceType Index Database
StartPage 688
SubjectTerms Age Factors
Aged
Chronic Disease - mortality
Comorbidity
Fee-for-Service Plans - statistics & numerical data
Female
Humans
Life Expectancy
Male
Medicare - statistics & numerical data
Retrospective Studies
Sex Factors
Socioeconomic Factors
United States - epidemiology
Title Multiple chronic conditions and life expectancy: a life table analysis
URI https://www.ncbi.nlm.nih.gov/pubmed/25023914
Volume 52
hasFullText
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LSwMxEA4-QAQRre8XOXiNdl_Nrjcp1iKth9JKbyXZzUKh3S1aL_56J5lNd6lV1B6WktBl2fky_ZKZ-YaQaykc6Qs3YpKrkPlScibTKGHKSYEv87oO_ehsi-dGe-A_DYNhJWKqq0vm8ib-WFlX8h-rwhjYVVfJ_sGyi5vCAHwH-8IVLAzXX9m4a7MBY5S41TnkCeZgmaDAZJwqo-Efz7UTxcJmMzg3FVOiUCSpMlQbudEpYSXLfcxRvRGId1nO0BTZeyLeWC-fmgPXl4lIxtPxIt1XN8HOX_GHKGJQCeJ3FE6U4CrOHhx_kfkGfx3WX3LmRCiWaR1q4FaAE1a8YwM7-H3x2qgG3O30UE3Sfhzsx1Ix5GxqLAm0zfUiLD79eXZJS9tOrZN12FXoNqn6bKeIOXHgora4MuK3qx5HS0cXt1jahhg60t8ju8U-gt4jKPbJmspqZKtbZErUyA6ex1IsMzsgLYsVWmCFllihgBWqYUFLrNxRgUMGKdQi5ZAMWg_9ZpsVPTRY7MODMhXEPPQU8Pp6mAoFZA2cLqzbVHhB5MgwTESQaBnHhgLqrhxgpLojQcqjADabqXCPyEaWZ-qEUNiYc08Ag_SU0uFjWOYu0B8RqjhJBHdOyTG-kdEMhVJG9l2dfTtzTrZLXF2QzRRWproEmjeXV8Y6nzYrTcE
linkProvider National Library of Medicine
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Multiple+chronic+conditions+and+life+expectancy%3A+a+life+table+analysis&rft.jtitle=Medical+care&rft.au=DuGoff%2C+Eva+H&rft.au=Canudas-Romo%2C+Vladimir&rft.au=Buttorff%2C+Christine&rft.au=Leff%2C+Bruce&rft.date=2014-08-01&rft.eissn=1537-1948&rft.volume=52&rft.issue=8&rft.spage=688&rft_id=info:doi/10.1097%2FMLR.0000000000000166&rft_id=info%3Apmid%2F25023914&rft_id=info%3Apmid%2F25023914&rft.externalDocID=25023914