Efficacy and safety of Bio 3D conduits composed of human umbilical cord–derived mesenchymal stromal cells: A proof-of-concept study in a canine ulnar nerve defect model - Fujita, Kazuaki; Ikeguchi, Ryosuke; Aoyama, Tomoki; Noguchi, Takashi; Yoshimoto, Koichi; Sakamoto, Daichi; Iwai, Terunobu; Miyamoto, Tetsuya; Miyazaki, Yudai; Akieda, Shizuka; Nagamura-Inoue, Tokiko; Nagamura, Fumitaka; et al. (Cell transplantation, 2025)
Keywords: Animals; Cell migration; Disease Models, Animal; Dogs; Humans; Mesenchymal Stem Cell Transplantation - methods; Mesenchymal stem cells; Mesenchymal Stem Cells - cytology; Mesenchymal Stem Cells - metabolism; Morbidity; Myelin; Nerve Regeneration - physiology; Original; Peripheral nerves; Proof of Concept Study; Regeneration; Stem cell transplantation; Stromal cells; Tissue Scaffolds - chemistry; Ulnar Nerve - injuries; Ulnar Nerve - pathology; Umbilical cord; Umbilical Cord - cytology; peripheral nerve injury; Bio 3D conduit; nerve regeneration; mesenchymal stromal cell; preclinical study; regenerative medicine