Human Parechovirus as a Cause of Isolated Pediatric Acute Liver Failure

• Published in: Pediatrics (Evanston) Vol. 138; no. 5
• Main Authors: Bigelow, Amee M, Scott, John P, Hong, Johnny C, Cronin, David C, Vitola, Bernadette E, Fons, Roger A, Petersen, Tara L
• Format: Journal Article
• Language: English
• Published: United States 01.11.2016
• Subjects: Female; Humans; Ileal Diseases - etiology; Ileal Diseases - surgery; Infant; Intussusception - etiology; Intussusception - surgery; Jejunal Diseases - etiology; Jejunal Diseases - surgery; Liver Failure, Acute - surgery; Liver Failure, Acute - virology; Liver Transplantation; Parechovirus - isolation & purification; Picornaviridae Infections - complications; Picornaviridae Infections - diagnosis; Postoperative Complications; RNA, Viral - blood

Among infants, almost half of acute liver failure cases are classified as indeterminate, whereas only a small number of cases show a documented viral infection. We present the first reported case of isolated acute hepatic failure in an infant in the setting of a human parechovirus (HPeV) infection....