Linking the future of anticancer metal-complexes to the therapy of tumour metastases

• Published in: Chemical Society reviews Vol. 44; no. 24; pp. 8818 - 8835
• Main Authors: Bergamo, Alberta, Sava, Gianni
• Format: Journal Article
• Language: English
• Published: England 21.12.2015
• Subjects: Antineoplastic Agents - therapeutic use; Coordination Complexes - therapeutic use; drug therapy; Drugs; Grounds; Humans; Joining; Medical services; metastasis; Migration; Neoplasm Metastasis - drug therapy; Neoplasm Metastasis - pathology; neoplasms; Patients; platinum; Ruthenium; Ruthenium - therapeutic use; Tumors

Cancer chemotherapy is almost always applied to patients with one or more diagnosed metastases and is expected to impact these lesions, thus providing significant benefits to the patient. The outcome of metastasis is determined by the interplay between the specific subpopulation of metastatic cells...