The Influence of Endogenous Testosterone Density on Unfavorable Disease and Tumor Load at Final Pathology in Intermediate-Risk Prostate Cancer: Results in 338 Patients Treated with Radical Prostatectomy and Extended Pelvic Lymph Node Dissection

• Published in: Urologia internationalis p. 1
• Main Authors: Porcaro, Antonio Benito, Panunzio, Andrea, Tafuri, Alessandro, Cerrato, Clara, Gallina, Sebastian, Bianchi, Alberto, Rizzetto, Riccardo, Amigoni, Nelia, Gozzo, Alessandra, Serafin, Emanuele, Cianflone, Francesco, Migliorini, Filippo, Vidiri, Stefano, Di Filippo, Giacomo, Novella, Giovanni, Brunelli, Matteo, Shakir, Aliasger, Pagliarulo, Vincenzo, Cerruto, Maria Angela, Siracusano, Salvatore, Antonelli, Alessandro
• Format: Journal Article
• Language: English
• Published: Switzerland 01.09.2022
• Subjects: Unfavorable disease; Tumor upgrading; Intermediate-risk prostate cancer; Prostate-specific antigen; Endogenous testosterone; Tumor upstaging; Extended pelvic lymph node dissection; Prostate-specific antigen density; Endogenous testosterone density; Percentage of biopsy positive cores density; Radical prostatectomy; Lymph node invasion; Prostate cancer

The aim of this study is to evaluate the influence of endogenous testosterone density (ETD) on features of aggressive prostate cancer (PCa) in intermediate-risk disease treated with radical prostatectomy and extended pelvic lymph node dissection. Density measurements included the ratio of endogenous...