Orthogonal polarization spectral imaging: A new method for study of the microcirculation

• Published in: Nature medicine Vol. 5; no. 10; pp. 1209 - 1212
• Main Authors: Groner, Warren, Winkelman, James W., Harris, Anthony G., Ince, Can, Bouma, Gerrit J., Messmer, Konrad, Nadeau, Richard G.
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.10.1999
• Subjects: Animals; Biomedicine; Brain - blood supply; Brain - surgery; Cancer Research; coronary heart disease; Cricetinae; Diagnostic Imaging - instrumentation; Humans; Infectious Diseases; Light; Metabolic Diseases; Microcirculation - pathology; Molecular Medicine; Neurosciences; on-the-market; Photons; Skin - blood supply; Tongue - blood supply

Different disease states, including diabetes, hypertension and coronary heart disease, produce distinctive microvascular pathologies. So far, imaging of the human microcirculation has been limited to vascular beds in which the vessels are visible and close to the surface (for example, nailfold, conj...