A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus

• Published in: Science translational medicine Vol. 11; no. 522
• Main Authors: Hobson-Peters, Jody, Harrison, Jessica J, Watterson, Daniel, Hazlewood, Jessamine E, Vet, Laura J, Newton, Natalee D, Warrilow, David, Colmant, Agathe M G, Taylor, Carmel, Huang, Bixing, Piyasena, Thisun B H, Chow, Weng Kong, Setoh, Yin Xiang, Tang, Bing, Nakayama, Eri, Yan, Kexin, Amarilla, Alberto A, Wheatley, Sarah, Moore, Peter R, Finger, Mitchell, Kurucz, Nina, Modhiran, Naphak, Young, Paul R, Khromykh, Alexander A, Bielefeldt-Ohmann, Helle, Suhrbier, Andreas, Hall, Roy A
• Format: Journal Article
• Language: English
• Published: United States 11.12.2019

Flaviviruses such as dengue, yellow fever, Zika, West Nile, and Japanese encephalitis virus present substantial global health burdens. New vaccines are being sought to address safety and manufacturing issues associated with current live attenuated vaccines. Here, we describe a new insect-specific fl...