Normal superoxide dismutase (SOD) gene in pregnancy-induced hypertension: is the decreased SOD activity a secondary phenomenon?

• Published in: Free radical research Vol. 21; no. 2; p. 59
• Main Authors: Chen, G, Wilson, R, Boyd, P, Mckillop, J H, Leitch, C, Walker, J J, Burdon, R H
• Format: Journal Article
• Language: English
• Published: England 01.01.1994
• Subjects: Adult; Blotting, Northern; DNA - blood; Female; Humans; Hypertension - enzymology; Leukocytes - chemistry; Pregnancy; Pregnancy Complications, Cardiovascular - enzymology; RNA, Messenger - blood; Superoxide Dismutase - blood; Superoxide Dismutase - genetics

Reactive oxygen species (ROS) have been implicated in the pathogenesis of pregnancy-induced hypertension (PIH). A genetic factor is also thought to be associated with the disease. The aim of the present study was to investigate whether decreased superoxide dismutase (SOD) activity in PIH resulted fr...