QuEChERS sample pre-processing with UPLC–MS/MS: A method for detecting 19 quinolone-based veterinary drugs in goat’s milk

• Published in: Food chemistry Vol. 373; no. Pt B; p. 131466
• Main Authors: Bang Ye, Siou, Huang, Ying, Lin, Ding-Yan
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 30.03.2022
• Subjects: Animals; Central composite design; Chromatography, High Pressure Liquid; Chromatography, Liquid; food chemistry; formic acid; goat milk; Goats; hydrogen; Milk; Plackett–Burman; QuEChERS; Quinolones; separation; sodium citrate; Solid Phase Extraction; Taiwan; Tandem Mass Spectrometry; UPLC–MS/MS; Validation; Veterinary Drugs; Taiwan; Validation; Central composite design; Plackett–Burman; UPLC–MS/MS; QuEChERS; Quinolones

•QuEChERS + UPLC–MS/MS was used to determine and identify quinolones in goat’s milk.•Plackett–Burman and CCD methods identified efficient extraction parameters.•The developed method meets the validation specifications of the TFDA.•The method is suitable for the routine analysis of quinolones in goat...