QuEChERS sample pre-processing with UPLC–MS/MS: A method for detecting 19 quinolone-based veterinary drugs in goat’s milk
•QuEChERS + UPLC–MS/MS was used to determine and identify quinolones in goat’s milk.•Plackett–Burman and CCD methods identified efficient extraction parameters.•The developed method meets the validation specifications of the TFDA.•The method is suitable for the routine analysis of quinolones in goat...
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| Published in | Food chemistry Vol. 373; no. Pt B; p. 131466 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Elsevier Ltd
30.03.2022
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| Subjects | |
| Online Access | Get full text |
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| Abstract | •QuEChERS + UPLC–MS/MS was used to determine and identify quinolones in goat’s milk.•Plackett–Burman and CCD methods identified efficient extraction parameters.•The developed method meets the validation specifications of the TFDA.•The method is suitable for the routine analysis of quinolones in goat’s milk.
We develop and validate a method for the rapid determination and identification of 19 quinolones in goat’s milk by combining the QuEChERS technique with ultra-performance liquid chromatography–tandem mass spectrometry. Plackett–Burman and Central Composite Design methods were used to select the parameters that best promote the extraction efficiency, which led to extraction with acetonitrile/5% formic acid, followed by phase separation with sodium citrate, disodium hydrogen citrate, Na2SO4, and NaCl as optimal. The supernatant was then extracted and cleaned by dispersive solid-phase extraction using C18 and Na2SO4 aided by low-temperature clean-up. The method was validated, with limits of quantification (LOQs) of 5 ppb, specificities of 1/5 LOQ, linearities (R2) > 0.9853, recoveries of 73.4–114.2%, repeatabilities < 15.0%, and intermediate precisions < 13.6%. The developed method was suitable for the routine analysis of quinolone residues in goat’s milk and was used to test 10 goat milk samples produced in Taiwan. |
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| AbstractList | We develop and validate a method for the rapid determination and identification of 19 quinolones in goat's milk by combining the QuEChERS technique with ultra-performance liquid chromatography-tandem mass spectrometry. Plackett-Burman and Central Composite Design methods were used to select the parameters that best promote the extraction efficiency, which led to extraction with acetonitrile/5% formic acid, followed by phase separation with sodium citrate, disodium hydrogen citrate, Na
SO
, and NaCl as optimal. The supernatant was then extracted and cleaned by dispersive solid-phase extraction using C
and Na
SO
aided by low-temperature clean-up. The method was validated, with limits of quantification (LOQs) of 5 ppb, specificities of 1/5 LOQ, linearities (R
) > 0.9853, recoveries of 73.4-114.2%, repeatabilities < 15.0%, and intermediate precisions < 13.6%. The developed method was suitable for the routine analysis of quinolone residues in goat's milk and was used to test 10 goat milk samples produced in Taiwan. We develop and validate a method for the rapid determination and identification of 19 quinolones in goat’s milk by combining the QuEChERS technique with ultra-performance liquid chromatography–tandem mass spectrometry. Plackett–Burman and Central Composite Design methods were used to select the parameters that best promote the extraction efficiency, which led to extraction with acetonitrile/5% formic acid, followed by phase separation with sodium citrate, disodium hydrogen citrate, Na₂SO₄, and NaCl as optimal. The supernatant was then extracted and cleaned by dispersive solid-phase extraction using C₁₈ and Na₂SO₄ aided by low-temperature clean-up. The method was validated, with limits of quantification (LOQs) of 5 ppb, specificities of 1/5 LOQ, linearities (R²) > 0.9853, recoveries of 73.4–114.2%, repeatabilities < 15.0%, and intermediate precisions < 13.6%. The developed method was suitable for the routine analysis of quinolone residues in goat’s milk and was used to test 10 goat milk samples produced in Taiwan. We develop and validate a method for the rapid determination and identification of 19 quinolones in goat's milk by combining the QuEChERS technique with ultra-performance liquid chromatography-tandem mass spectrometry. Plackett-Burman and Central Composite Design methods were used to select the parameters that best promote the extraction efficiency, which led to extraction with acetonitrile/5% formic acid, followed by phase separation with sodium citrate, disodium hydrogen citrate, Na2SO4, and NaCl as optimal. The supernatant was then extracted and cleaned by dispersive solid-phase extraction using C18 and Na2SO4 aided by low-temperature clean-up. The method was validated, with limits of quantification (LOQs) of 5 ppb, specificities of 1/5 LOQ, linearities (R2) > 0.9853, recoveries of 73.4-114.2%, repeatabilities < 15.0%, and intermediate precisions < 13.6%. The developed method was suitable for the routine analysis of quinolone residues in goat's milk and was used to test 10 goat milk samples produced in Taiwan.We develop and validate a method for the rapid determination and identification of 19 quinolones in goat's milk by combining the QuEChERS technique with ultra-performance liquid chromatography-tandem mass spectrometry. Plackett-Burman and Central Composite Design methods were used to select the parameters that best promote the extraction efficiency, which led to extraction with acetonitrile/5% formic acid, followed by phase separation with sodium citrate, disodium hydrogen citrate, Na2SO4, and NaCl as optimal. The supernatant was then extracted and cleaned by dispersive solid-phase extraction using C18 and Na2SO4 aided by low-temperature clean-up. The method was validated, with limits of quantification (LOQs) of 5 ppb, specificities of 1/5 LOQ, linearities (R2) > 0.9853, recoveries of 73.4-114.2%, repeatabilities < 15.0%, and intermediate precisions < 13.6%. The developed method was suitable for the routine analysis of quinolone residues in goat's milk and was used to test 10 goat milk samples produced in Taiwan. •QuEChERS + UPLC–MS/MS was used to determine and identify quinolones in goat’s milk.•Plackett–Burman and CCD methods identified efficient extraction parameters.•The developed method meets the validation specifications of the TFDA.•The method is suitable for the routine analysis of quinolones in goat’s milk. We develop and validate a method for the rapid determination and identification of 19 quinolones in goat’s milk by combining the QuEChERS technique with ultra-performance liquid chromatography–tandem mass spectrometry. Plackett–Burman and Central Composite Design methods were used to select the parameters that best promote the extraction efficiency, which led to extraction with acetonitrile/5% formic acid, followed by phase separation with sodium citrate, disodium hydrogen citrate, Na2SO4, and NaCl as optimal. The supernatant was then extracted and cleaned by dispersive solid-phase extraction using C18 and Na2SO4 aided by low-temperature clean-up. The method was validated, with limits of quantification (LOQs) of 5 ppb, specificities of 1/5 LOQ, linearities (R2) > 0.9853, recoveries of 73.4–114.2%, repeatabilities < 15.0%, and intermediate precisions < 13.6%. The developed method was suitable for the routine analysis of quinolone residues in goat’s milk and was used to test 10 goat milk samples produced in Taiwan. |
| ArticleNumber | 131466 |
| Author | Bang Ye, Siou Huang, Ying Lin, Ding-Yan |
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| Cites_doi | 10.1016/j.chroma.2017.11.050 10.1016/j.chroma.2011.05.005 10.1016/j.foodchem.2011.01.098 10.1093/oxfordjournals.jac.a020889 10.1007/s00216-008-2300-9 10.1016/j.trac.2014.06.020 10.1080/10408347.2013.835244 10.1016/j.chroma.2017.09.036 10.1093/jaoac/86.2.412 10.1016/j.aca.2019.02.036 10.1016/j.chroma.2014.06.034 10.1016/j.anifeedsci.2014.09.018 10.1080/10408390701761878 10.1016/j.foodcont.2014.10.027 10.1016/j.indcrop.2012.07.011 10.1016/j.foodchem.2016.04.077 10.1016/j.jpba.2018.03.029 10.1016/j.foodcont.2016.03.001 10.1016/j.foodchem.2011.03.042 10.1016/j.trac.2019.06.012 10.1002/jssc.201501204 10.1016/j.chroma.2011.05.066 10.1016/j.talanta.2012.02.011 |
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| Keywords | Validation Central composite design Plackett–Burman UPLC–MS/MS QuEChERS Quinolones |
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| References | TFDA of the Ministry of Health and Welfare (b0150) 2020 Herrera-Herrera, Hernández-Borges, Rodríguez-Delgado, Herrero, Cifuentes (b0095) 2011; 1218 Australia (2019). Agricultural and Veterinary Chemicals Code (MRL Standard) Instrument 2019. Compilation No. 11, 1–304. CODEX. Codex Alimentarius. (2018). Maximum Residue Limits (MRLs) and Risk Management Recommendations (RMRS) for Residues of Veterinary Drugs in Foods CAC/MRL 2–2018. Retrieved from http://www.fao.org/fao-who-codexalimentarius/sh-proxy/en/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FStandards%252FCXM%2B2%252FMRL2e.pdf. Accessed [May 11, 2021]. Majors (b0120) 2007; 25 Anastassiades, Lehotay, Štajnbaher, Schenck (b0015) 2003; 86 Díaz-Alvarez, Turiel, Martín-Esteban (b0060) 2009; 393 8. Retrieved from https://op.europa.eu/en/publication-detail/-/publication/ed928116-a955-4a84-b10a-cf7a82bad858/language-en. Accessed [May 11, 2021]. 189–199. Doi: 10.1016/j.foodchem.2016.04.077. Lombardo-Agüí, García-Campaña, Crices-Blanco, Gámiz-Gracia (b0110) 2015; 50 Frenich, Romero-González, Gómez-Pérez, Vidal (b0080) 2011; 1218 European Commission (2010). Council regulation N° 37/2010 de 22 de dezembro de 2009 relativo a substâncias farmacologicamente ativas e respectiva classificação no que respeita aos limites máximos de resíduos nos alimentos de origem animal. Zhang, Deng, Zheng, Zhang, Yang, Liao, Luo (b0160) 2019; 118 Frenich, Romero-González, del Mar Aguilera-Luiz (b0075) 2014; 63 Perestrelo, Silva, Porto-Figuera, Periera, Silva, Medina, Câmara (b0130) 2019; 1070 Georgakopoulos, P., Zachari, R., Mataragas, M., Athanasopoulos, P., Drosinos, E. H., & Skandamis., P. N. (2011). Optimisation of octadecyl (C 1–72. Retrieved from https://eur-lex.europa.eu/legal-content/PT/TXT/PDF/?uri=CELEX:32010R0037&from=DE. Accessed [May 11, 2021]. Cabrera, Caldas, Prestes, Primel, Zanella (b0045) 2016; 39 Center for Disease Control and Prevention U.S., CDC (2013). Antibiotic resistant threats in the United States, 2013. The threat of antibiotic resistance (Section 1). Retrieved from https://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf. Accessed [May 11, 2021]. Zhou, Xu, Cong, Cai, Zhang, Wang, Ren (b0165) 2018; 1532 European Commission (2002). 2002/657/EC: Commission decision of 12 August 2002 implementing council directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Borges, P. R. S., Tavares, E. G., Guimarães, I. C., de Paulo Rocha, R., Araujo, A. B. S., Nunes, E. E., & de Barros Vilas Boas, E. V. (2016). Obtaining a protocol for extraction of phenolics from açaí fruit pulp through Plackett–Burman design and response surface methodology. Rodríguez, Moreno-Bondi, Marazuela (b0135) 2011; 127 Jakimska, Kot-Wasik, Namieśnik (b0100) 2014; 44 Barreto, Ribeiro, Hoff, Costa (b0030) 2017; 1521 Grande-Martínez, Moreno-González, Arrebola-Liébanas, Garrido-Frenich, García-Campaña (b0090) 2018; 155 Makkar, Ankers (b0125) 2014; 198 Beyer, Biziuk (b0035) 2008; 48 536–542. Doi: 10.1016/j.foodchem.2011.03.042. Anastácio, Carvalho (b0005) 2013; 43 USA. (2020). https://bcglobal.bryantchristie.com/db#pesticides/query. Accessed [May 11, 2021]. Ronquillo, Hernandez (b0140) 2017; 72 Anastassiades (b0010) 2006 Lombardo-Agüí, García-Campana, Gámiz-Gracia, Cruces-Blanco (b0115) 2012; 93 TFDA of the Ministry of Health and Welfare (2019). Quality control regulations in the guidelines for the validation of food chemical methods. Retrieved from https://www.rootlaw.com.tw/LawContent.aspx?LawID=A040170051056900-1080314. Accessed [May 11, 2021]. sorbent amount in QuEChERS analytical method for the accurate organophosphorus pesticide residues determination in low-fatty baby foods with response surface methodology. Junza, Dorival-García, Zafra-Gómez, Barrón, Ballesteros, Barbosa, Navalón (b0105) 2014; 1356 Ball (b0025) 2000; 46 Anastassiades (10.1016/j.foodchem.2021.131466_b0010) Díaz-Alvarez (10.1016/j.foodchem.2021.131466_b0060) 2009; 393 Anastácio (10.1016/j.foodchem.2021.131466_b0005) 2013; 43 Ronquillo (10.1016/j.foodchem.2021.131466_b0140) 2017; 72 10.1016/j.foodchem.2021.131466_b0070 Grande-Martínez (10.1016/j.foodchem.2021.131466_b0090) 2018; 155 10.1016/j.foodchem.2021.131466_b0155 10.1016/j.foodchem.2021.131466_b0055 Herrera-Herrera (10.1016/j.foodchem.2021.131466_b0095) 2011; 1218 Perestrelo (10.1016/j.foodchem.2021.131466_b0130) 2019; 1070 10.1016/j.foodchem.2021.131466_b0050 Barreto (10.1016/j.foodchem.2021.131466_b0030) 2017; 1521 Junza (10.1016/j.foodchem.2021.131466_b0105) 2014; 1356 Jakimska (10.1016/j.foodchem.2021.131466_b0100) 2014; 44 Zhang (10.1016/j.foodchem.2021.131466_b0160) 2019; 118 Cabrera (10.1016/j.foodchem.2021.131466_b0045) 2016; 39 Lombardo-Agüí (10.1016/j.foodchem.2021.131466_b0110) 2015; 50 TFDA of the Ministry of Health and Welfare (10.1016/j.foodchem.2021.131466_b0150) Frenich (10.1016/j.foodchem.2021.131466_b0075) 2014; 63 Ball (10.1016/j.foodchem.2021.131466_b0025) 2000; 46 10.1016/j.foodchem.2021.131466_b0065 10.1016/j.foodchem.2021.131466_b0020 10.1016/j.foodchem.2021.131466_b0085 Majors (10.1016/j.foodchem.2021.131466_b0120) 2007; 25 Anastassiades (10.1016/j.foodchem.2021.131466_b0015) 2003; 86 10.1016/j.foodchem.2021.131466_b0040 Frenich (10.1016/j.foodchem.2021.131466_b0080) 2011; 1218 Rodríguez (10.1016/j.foodchem.2021.131466_b0135) 2011; 127 Beyer (10.1016/j.foodchem.2021.131466_b0035) 2008; 48 Lombardo-Agüí (10.1016/j.foodchem.2021.131466_b0115) 2012; 93 Makkar (10.1016/j.foodchem.2021.131466_b0125) 2014; 198 Zhou (10.1016/j.foodchem.2021.131466_b0165) 2018; 1532 10.1016/j.foodchem.2021.131466_b0145 |
| References_xml | – reference: Georgakopoulos, P., Zachari, R., Mataragas, M., Athanasopoulos, P., Drosinos, E. H., & Skandamis., P. N. (2011). Optimisation of octadecyl (C – reference: , 8. Retrieved from https://op.europa.eu/en/publication-detail/-/publication/ed928116-a955-4a84-b10a-cf7a82bad858/language-en. Accessed [May 11, 2021]. – volume: 127 start-page: 1354 year: 2011 end-page: 1360 ident: b0135 article-title: Multiresidue determination of fluoroquinolone antimicrobials in baby foods by liquid chromatography publication-title: Food Chemistry – reference: , 1–72. Retrieved from https://eur-lex.europa.eu/legal-content/PT/TXT/PDF/?uri=CELEX:32010R0037&from=DE. Accessed [May 11, 2021]. – reference: USA. (2020). https://bcglobal.bryantchristie.com/db#pesticides/query. Accessed [May 11, 2021]. – volume: 1532 start-page: 20 year: 2018 end-page: 29 ident: b0165 article-title: Optimization for quick, easy, cheap, effective, rugged and safe extraction of mycotoxins and veterinary drugs by response surface methodology for application to egg and milk publication-title: Journal of Chromatography A – volume: 86 start-page: 412 year: 2003 end-page: 431 ident: b0015 article-title: Fast and easy multiresidue method employing acetonitrile extraction/partitioning and “dispersive solid-phase extraction” for the determination of pesticide residues in produce publication-title: Journal of AOAC INTERNATIONAL – reference: , 189–199. Doi: 10.1016/j.foodchem.2016.04.077. – volume: 46 start-page: 17 year: 2000 end-page: 24 ident: b0025 article-title: Quinolone generations: Natural history or natural selection? publication-title: Journal of Antimicrobial Chemotherapy – reference: ) sorbent amount in QuEChERS analytical method for the accurate organophosphorus pesticide residues determination in low-fatty baby foods with response surface methodology. – year: 2020 ident: b0150 article-title: Standards for veterinary drug residue limits in foods – reference: CODEX. Codex Alimentarius. (2018). Maximum Residue Limits (MRLs) and Risk Management Recommendations (RMRS) for Residues of Veterinary Drugs in Foods CAC/MRL 2–2018. Retrieved from http://www.fao.org/fao-who-codexalimentarius/sh-proxy/en/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FStandards%252FCXM%2B2%252FMRL2e.pdf. Accessed [May 11, 2021]. – volume: 44 start-page: 277 year: 2014 end-page: 298 ident: b0100 article-title: The current state-of-the-art in the determination of pharmaceutical residues in environmental matrices using hyphenated techniques publication-title: Critical Reviews in Analytical Chemistry – volume: 93 start-page: 193 year: 2012 end-page: 199 ident: b0115 article-title: Determination of quinolones of veterinary use in bee products by ultra-high performance liquid chromatography–tandem mass spectrometry using a QuEChERS extraction procedure publication-title: Talanta – reference: Center for Disease Control and Prevention U.S., CDC (2013). Antibiotic resistant threats in the United States, 2013. The threat of antibiotic resistance (Section 1). Retrieved from https://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf. Accessed [May 11, 2021]. – reference: , 536–542. Doi: 10.1016/j.foodchem.2011.03.042. – volume: 1070 start-page: 1 year: 2019 end-page: 28 ident: b0130 article-title: QuEChERS - Fundamentals, relevant improvements, applications and future trends publication-title: Analytica Chimica Acta – year: 2006 ident: b0010 article-title: CRL-SRM 1st Joint CRL Workshop, Stuttgart – volume: 43 start-page: 99 year: 2013 end-page: 105 ident: b0005 article-title: Phenolics extraction from sweet potato peels: Key factors screening through a Placket-Burman design publication-title: Industrial Crops and Products – volume: 155 start-page: 27 year: 2018 end-page: 32 ident: b0090 article-title: Optimization of a modified QuEChERS method for the determination of tetracyclines in fish muscle by UHPLC-MS/MS publication-title: Journal of Pharmaceutical and Biomedical Analysis – volume: 39 start-page: 1945 year: 2016 end-page: 1954 ident: b0045 article-title: Evaluation of alternative sorbents for dispersive solid-phase extraction clean-up in the QuEChERS method for the determination of pesticide residues in rice by liquid chromatography with tandem mass spectrometry publication-title: Journal of Separation Science – volume: 1356 start-page: 10 year: 2014 end-page: 22 ident: b0105 article-title: Multiclass method for the determination of quinolones and -lactams, in raw cow milk using dispersive liquid-liquid microextraction and ultra high performance liquid chromatography–tandem mass spectrometry publication-title: Journal of Chromatography A – reference: TFDA of the Ministry of Health and Welfare (2019). Quality control regulations in the guidelines for the validation of food chemical methods. Retrieved from https://www.rootlaw.com.tw/LawContent.aspx?LawID=A040170051056900-1080314. Accessed [May 11, 2021]. – volume: 393 start-page: 899 year: 2009 end-page: 905 ident: b0060 article-title: Selective sample preparation for the analysis of (fluoro)quinolones in baby food: Molecularly imprinted polymers versus anion-exchange resins publication-title: Analytical and Bioanalytical Chemistry – volume: 1218 start-page: 7608 year: 2011 end-page: 7614 ident: b0095 article-title: Determination of quinolone residues in infant and young children powdered milk combining solid-phase extraction and ultra-performance liquid chromatography–tandem mass spectrometry publication-title: Journal of Chromatography A – volume: 48 start-page: 888 year: 2008 end-page: 904 ident: b0035 article-title: Methods for determining pesticides and polychlorinated biphenyls in food samples— problems and challenges publication-title: Critical Reviews in Food Science and Nutrition – volume: 198 start-page: 309 year: 2014 end-page: 322 ident: b0125 article-title: Towards sustainable animal diets: A survey-based study publication-title: Animal Feed Science and Technology – volume: 1521 start-page: 131 year: 2017 end-page: 139 ident: b0030 article-title: Development and validation of a high-throughput method for determination of nine fluoroquinolones residues in muscle of different animal species by liquid chromatography coupled to tandem mass spectrometry with low temperature clean up publication-title: Journal of Chromatography A – volume: 25 start-page: 436 year: 2007 end-page: 446 ident: b0120 article-title: QuEChERS - a new sample preparation technique for multiresidue analysis of pesticides in foods and agricultural samples publication-title: LCGC North America – reference: Australia (2019). Agricultural and Veterinary Chemicals Code (MRL Standard) Instrument 2019. Compilation No. 11, 1–304. – reference: Borges, P. R. S., Tavares, E. G., Guimarães, I. C., de Paulo Rocha, R., Araujo, A. B. S., Nunes, E. E., & de Barros Vilas Boas, E. V. (2016). Obtaining a protocol for extraction of phenolics from açaí fruit pulp through Plackett–Burman design and response surface methodology. – volume: 50 start-page: 864 year: 2015 end-page: 868 ident: b0110 article-title: Determination of quinolones in fish by ultra-high performance liquid chromatography with fluorescence detection using QuEChERS as sample treatment publication-title: Food Control – volume: 72 start-page: 255 year: 2017 end-page: 267 ident: b0140 article-title: Antibiotic and synthetic growth promoters in animal diets: Review of impact and analytical methods publication-title: Food Control – volume: 1218 start-page: 4349 year: 2011 end-page: 4356 ident: b0080 article-title: Multi-mycotoxin analysis in eggs using a QuEChERS-based extraction procedure and ultra-high-pressure liquid chromatography coupled to triple quadrupole mass spectrometry publication-title: Journal of Chromatography A – reference: European Commission (2002). 2002/657/EC: Commission decision of 12 August 2002 implementing council directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. – reference: European Commission (2010). Council regulation N° 37/2010 de 22 de dezembro de 2009 relativo a substâncias farmacologicamente ativas e respectiva classificação no que respeita aos limites máximos de resíduos nos alimentos de origem animal. – volume: 63 start-page: 158 year: 2014 end-page: 169 ident: b0075 article-title: Comprehensive analysis of toxics (pesticides, veterinary drugs and mycotoxins) in food by UHPLC-MS publication-title: TrAC Trends in Analytical Chemistry – volume: 118 start-page: 517 year: 2019 end-page: 537 ident: b0160 article-title: The application of the QuEChERS methodology in the determination of antibiotics in food: A review publication-title: TrAC Trends in Analytical Chemistry – ident: 10.1016/j.foodchem.2021.131466_b0145 – volume: 1532 start-page: 20 year: 2018 ident: 10.1016/j.foodchem.2021.131466_b0165 article-title: Optimization for quick, easy, cheap, effective, rugged and safe extraction of mycotoxins and veterinary drugs by response surface methodology for application to egg and milk publication-title: Journal of Chromatography A doi: 10.1016/j.chroma.2017.11.050 – ident: 10.1016/j.foodchem.2021.131466_b0065 – volume: 1218 start-page: 4349 issue: 28 year: 2011 ident: 10.1016/j.foodchem.2021.131466_b0080 article-title: Multi-mycotoxin analysis in eggs using a QuEChERS-based extraction procedure and ultra-high-pressure liquid chromatography coupled to triple quadrupole mass spectrometry publication-title: Journal of Chromatography A doi: 10.1016/j.chroma.2011.05.005 – volume: 127 start-page: 1354 issue: 3 year: 2011 ident: 10.1016/j.foodchem.2021.131466_b0135 article-title: Multiresidue determination of fluoroquinolone antimicrobials in baby foods by liquid chromatography publication-title: Food Chemistry doi: 10.1016/j.foodchem.2011.01.098 – volume: 46 start-page: 17 issue: supplement 3 year: 2000 ident: 10.1016/j.foodchem.2021.131466_b0025 article-title: Quinolone generations: Natural history or natural selection? publication-title: Journal of Antimicrobial Chemotherapy doi: 10.1093/oxfordjournals.jac.a020889 – volume: 393 start-page: 899 issue: 3 year: 2009 ident: 10.1016/j.foodchem.2021.131466_b0060 article-title: Selective sample preparation for the analysis of (fluoro)quinolones in baby food: Molecularly imprinted polymers versus anion-exchange resins publication-title: Analytical and Bioanalytical Chemistry doi: 10.1007/s00216-008-2300-9 – volume: 63 start-page: 158 year: 2014 ident: 10.1016/j.foodchem.2021.131466_b0075 article-title: Comprehensive analysis of toxics (pesticides, veterinary drugs and mycotoxins) in food by UHPLC-MS publication-title: TrAC Trends in Analytical Chemistry doi: 10.1016/j.trac.2014.06.020 – volume: 44 start-page: 277 issue: 3 year: 2014 ident: 10.1016/j.foodchem.2021.131466_b0100 article-title: The current state-of-the-art in the determination of pharmaceutical residues in environmental matrices using hyphenated techniques publication-title: Critical Reviews in Analytical Chemistry doi: 10.1080/10408347.2013.835244 – volume: 1521 start-page: 131 year: 2017 ident: 10.1016/j.foodchem.2021.131466_b0030 article-title: Development and validation of a high-throughput method for determination of nine fluoroquinolones residues in muscle of different animal species by liquid chromatography coupled to tandem mass spectrometry with low temperature clean up publication-title: Journal of Chromatography A doi: 10.1016/j.chroma.2017.09.036 – ident: 10.1016/j.foodchem.2021.131466_b0070 – ident: 10.1016/j.foodchem.2021.131466_b0055 – volume: 86 start-page: 412 year: 2003 ident: 10.1016/j.foodchem.2021.131466_b0015 article-title: Fast and easy multiresidue method employing acetonitrile extraction/partitioning and “dispersive solid-phase extraction” for the determination of pesticide residues in produce publication-title: Journal of AOAC INTERNATIONAL doi: 10.1093/jaoac/86.2.412 – ident: 10.1016/j.foodchem.2021.131466_b0020 – volume: 1070 start-page: 1 year: 2019 ident: 10.1016/j.foodchem.2021.131466_b0130 article-title: QuEChERS - Fundamentals, relevant improvements, applications and future trends publication-title: Analytica Chimica Acta doi: 10.1016/j.aca.2019.02.036 – volume: 1356 start-page: 10 year: 2014 ident: 10.1016/j.foodchem.2021.131466_b0105 article-title: Multiclass method for the determination of quinolones and -lactams, in raw cow milk using dispersive liquid-liquid microextraction and ultra high performance liquid chromatography–tandem mass spectrometry publication-title: Journal of Chromatography A doi: 10.1016/j.chroma.2014.06.034 – volume: 198 start-page: 309 year: 2014 ident: 10.1016/j.foodchem.2021.131466_b0125 article-title: Towards sustainable animal diets: A survey-based study publication-title: Animal Feed Science and Technology doi: 10.1016/j.anifeedsci.2014.09.018 – volume: 48 start-page: 888 issue: 10 year: 2008 ident: 10.1016/j.foodchem.2021.131466_b0035 article-title: Methods for determining pesticides and polychlorinated biphenyls in food samples— problems and challenges publication-title: Critical Reviews in Food Science and Nutrition doi: 10.1080/10408390701761878 – volume: 50 start-page: 864 year: 2015 ident: 10.1016/j.foodchem.2021.131466_b0110 article-title: Determination of quinolones in fish by ultra-high performance liquid chromatography with fluorescence detection using QuEChERS as sample treatment publication-title: Food Control doi: 10.1016/j.foodcont.2014.10.027 – volume: 43 start-page: 99 year: 2013 ident: 10.1016/j.foodchem.2021.131466_b0005 article-title: Phenolics extraction from sweet potato peels: Key factors screening through a Placket-Burman design publication-title: Industrial Crops and Products doi: 10.1016/j.indcrop.2012.07.011 – ident: 10.1016/j.foodchem.2021.131466_b0040 doi: 10.1016/j.foodchem.2016.04.077 – volume: 25 start-page: 436 year: 2007 ident: 10.1016/j.foodchem.2021.131466_b0120 article-title: QuEChERS - a new sample preparation technique for multiresidue analysis of pesticides in foods and agricultural samples publication-title: LCGC North America – volume: 155 start-page: 27 year: 2018 ident: 10.1016/j.foodchem.2021.131466_b0090 article-title: Optimization of a modified QuEChERS method for the determination of tetracyclines in fish muscle by UHPLC-MS/MS publication-title: Journal of Pharmaceutical and Biomedical Analysis doi: 10.1016/j.jpba.2018.03.029 – ident: 10.1016/j.foodchem.2021.131466_b0150 – ident: 10.1016/j.foodchem.2021.131466_b0050 – volume: 72 start-page: 255 year: 2017 ident: 10.1016/j.foodchem.2021.131466_b0140 article-title: Antibiotic and synthetic growth promoters in animal diets: Review of impact and analytical methods publication-title: Food Control doi: 10.1016/j.foodcont.2016.03.001 – ident: 10.1016/j.foodchem.2021.131466_b0010 – ident: 10.1016/j.foodchem.2021.131466_b0085 doi: 10.1016/j.foodchem.2011.03.042 – volume: 118 start-page: 517 year: 2019 ident: 10.1016/j.foodchem.2021.131466_b0160 article-title: The application of the QuEChERS methodology in the determination of antibiotics in food: A review publication-title: TrAC Trends in Analytical Chemistry doi: 10.1016/j.trac.2019.06.012 – ident: 10.1016/j.foodchem.2021.131466_b0155 – volume: 39 start-page: 1945 issue: 10 year: 2016 ident: 10.1016/j.foodchem.2021.131466_b0045 article-title: Evaluation of alternative sorbents for dispersive solid-phase extraction clean-up in the QuEChERS method for the determination of pesticide residues in rice by liquid chromatography with tandem mass spectrometry publication-title: Journal of Separation Science doi: 10.1002/jssc.201501204 – volume: 1218 start-page: 7608 issue: 42 year: 2011 ident: 10.1016/j.foodchem.2021.131466_b0095 article-title: Determination of quinolone residues in infant and young children powdered milk combining solid-phase extraction and ultra-performance liquid chromatography–tandem mass spectrometry publication-title: Journal of Chromatography A doi: 10.1016/j.chroma.2011.05.066 – volume: 93 start-page: 193 year: 2012 ident: 10.1016/j.foodchem.2021.131466_b0115 article-title: Determination of quinolones of veterinary use in bee products by ultra-high performance liquid chromatography–tandem mass spectrometry using a QuEChERS extraction procedure publication-title: Talanta doi: 10.1016/j.talanta.2012.02.011 |
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| Snippet | •QuEChERS + UPLC–MS/MS was used to determine and identify quinolones in goat’s milk.•Plackett–Burman and CCD methods identified efficient extraction... We develop and validate a method for the rapid determination and identification of 19 quinolones in goat's milk by combining the QuEChERS technique with... We develop and validate a method for the rapid determination and identification of 19 quinolones in goat’s milk by combining the QuEChERS technique with... |
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| StartPage | 131466 |
| SubjectTerms | Animals Central composite design Chromatography, High Pressure Liquid Chromatography, Liquid food chemistry formic acid goat milk Goats hydrogen Milk Plackett–Burman QuEChERS Quinolones separation sodium citrate Solid Phase Extraction Taiwan Tandem Mass Spectrometry UPLC–MS/MS Validation Veterinary Drugs |
| Title | QuEChERS sample pre-processing with UPLC–MS/MS: A method for detecting 19 quinolone-based veterinary drugs in goat’s milk |
| URI | https://dx.doi.org/10.1016/j.foodchem.2021.131466 https://www.ncbi.nlm.nih.gov/pubmed/34731812 https://www.proquest.com/docview/2593593413 https://www.proquest.com/docview/2636535224 |
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