Importance of the pig as a human biomedical model

• Published in: Science translational medicine Vol. 13; no. 621; p. eabd5758
• Main Authors: Lunney, Joan K, Van Goor, Angelica, Walker, Kristen E, Hailstock, Taylor, Franklin, Jasmine, Dai, Chaohui
• Format: Journal Article
• Language: English
• Published: United States 24.11.2021
• Subjects: Animals; Biomedical Research; Disease Models, Animal; Genome; Humans; Models, Animal; Swine

Pigs have substantial potential as biomedical models for studying human developmental processes, congenital diseases, and pathogen response mechanisms in addition to utility as xenotransplant organ donors and tools for vaccine and drug design. The similarity of pigs to humans in anatomical size and...