Anti-oxidation and anti-aging activity of polysaccharide from Malus micromalus Makino fruit wine

• Published in: International journal of biological macromolecules Vol. 121; pp. 1203 - 1212
• Main Authors: Hui, Yang, Jun-li, Hua, Chuang, Wang
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2019
• Subjects: 2,2-diphenyl-1-picrylhydrazyl; Aging - drug effects; Animals; Anti-aging activity; anti-aging properties; Anti-oxidation; apoptosis; Apoptosis - drug effects; cellulose; cerebral cortex; Cerebral Cortex - cytology; dialysis; Fourier transform infrared spectroscopy; fractionation; Free Radical Scavengers - chemistry; Free Radical Scavengers - pharmacology; free radicals; Free Radicals - chemistry; freeze drying; fructose; Fruit - chemistry; fruit wines; galactose; gel chromatography; glucose; hydrazine; hydroxyl radicals; lipid peroxides; Malus - chemistry; Malus micromalus; Malus micromalus Makino fruit wine; mannose; Mice; Molecular Weight; Monosaccharides - analysis; Neurons - cytology; Neurons - drug effects; Polysaccharide; Polysaccharides - chemistry; Polysaccharides - pharmacology; porous media; raw materials; superoxide anion; water solubility; Malus micromalus Makino fruit wine; Polysaccharide; Anti-oxidation; Anti-aging activity

Malus micromalus Makino fruit wine was used as a raw material and a water soluble polysaccharide (MWP-2) was successfully separated from it by fractionated extraction, alcohol precipitation, macroporous resin purification, cellulose column purification, running water dialysis, and vacuum freeze dryi...