DNA–magnetite nanocomposite materials

It is shown here that magnetite nanoparticles can be associated with double-stranded DNA. In a first step, a complex of DNA with Fe 2+ and Fe 3+ ions is formed. +Then, in a second step, magnetite nanoparticles are formed by increasing the pH. As shown by electrophoresis, the nanoparticles are strong...

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Bibliographic Details
Published inMaterials letters Vol. 42; no. 3; pp. 183 - 188
Main Authors Mornet, S, Vekris, A, Bonnet, J, Duguet, E, Grasset, F, Choy, J.-H, Portier, J
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier B.V 2000
Elsevier
Subjects
Biohybrids
Biological and medical sciences
Biotechnology
Chemical Sciences
DNA
Electrophoresis
Fundamental and applied biological sciences. Psychology
Hybrids
Magnetite
Material chemistry
Methods. Procedures. Technologies
Mossbauer spectroscopy
Nanoparticles
Others
Particles (particulate matter)
pH effects
Transmission electron microscopy
Various methods and equipments
Nanoparticles
Hybrids
Magnetite
DNA
Biohybrids
Nanocomposite
Nucleic acid
Composite material
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Summary:It is shown here that magnetite nanoparticles can be associated with double-stranded DNA. In a first step, a complex of DNA with Fe 2+ and Fe 3+ ions is formed. +Then, in a second step, magnetite nanoparticles are formed by increasing the pH. As shown by electrophoresis, the nanoparticles are strongly attached to the nucleic acid. From TEM imaging and Mössbauer measurement, a tentative model for the textural organization of DNA and magnetite is proposed.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0167-577X
1873-4979
DOI:10.1016/S0167-577X(99)00181-0