Comparative pharmacokinetics of the main active components in normal and ulcerative colitis rats after oral administration of Zingiberis Rhizoma–Ginseng Radix et Rhizoma herb pair and its single herb extracts by LC–MS/MS - Wan, Yue; Dong, Zhiling; Li, Huifang; Yang, Lei; Li, Wenwen; Zhu, Ke; Jiang, Shu; Qian, Dawei; Duan, Jinao (Journal of separation science, 2022)
Keywords: Administration, Oral; Animals; chemical species; Chromatography, High Pressure Liquid - methods; Chromatography, Liquid; Colitis, Ulcerative - drug therapy; Correlation coefficients; Drugs, Chinese Herbal - analysis; Gingerol; ginsenosides; herb pair; Herbs; Inflammatory bowel disease; Liquid chromatography; Mass spectrometry; Oral administration; Panax; Panax - chemistry; Pharmacokinetics; Pharmacology; Plant Extracts; Rats; rhizomes; separation; synergism; Synergistic effect; tandem mass spectrometry; Tandem Mass Spectrometry - methods; ulcerative colitis; Zingiber officinale; pharmacokinetics; herb pair; liquid chromatography; ulcerative colitis