Rapid Identification of the Receptor-Binding Specificity of Influenza A Viruses by Fluorogenic Glycofoldamers

• Published in: Angewandte Chemie International Edition Vol. 55; no. 45; pp. 13995 - 13999
• Main Authors: He, Xiao-Peng, Zeng, Ya-Li, Tang, Xin-Ying, Li, Na, Zhou, Dong-Ming, Chen, Guo-Rong, Tian, He
• Format: Journal Article
• Language: English
• Published: Germany Blackwell Publishing Ltd 02.11.2016
• Subjects: fluorescence spectroscopy; foldamers; glycans; high-throughput screening; influenza; influenza; fluorescence spectroscopy; glycans; high-throughput screening; foldamers

The re‐emergence of influenza raises a global concern that viral pandemics can unpredictably occur. However, effective approaches that can probe the infection risk of influenza viruses for humans are rare. In this work, we develop a glycofoldamer that can rapidly identify the glycan‐receptor specifi...