Development and validation of a hydrophilic interaction liquid chromatography‐tandem mass spectrometry method for the quantification of regadenoson in human plasma and its pharmacokinetic application - Wang, Dun‐Jian; Wang, Da‐Wei; Fang, Qiu‐Chen; Shen, Ye; Zeng, Nv‐Jin; Yang, Yan‐Ling; Zhang, Hong‐Wen; Wang, Yong‐Qing; Sun, Lu‐Ning (Journal of separation science, 2022)
Keywords: Acetonitrile; Adenosine; agonists; Ammonium acetate; Blood plasma; calibration; Cardiac stress tests; Chromatography, High Pressure Liquid; Chromatography, Liquid - methods; exercise; Humans; hydrophilic interaction liquid chromatography; hydrophilicity; Hydrophobic and Hydrophilic Interactions; Ions; Liquid chromatography; Mass spectrometry; Pharmacokinetics; Pharmacology; Purines; Pyrazoles; Radioisotopes; regadenoson, tandem mass spectrometry; Reproducibility of Results; Scientific imaging; separation; Spectroscopy; tandem mass spectrometry; Tandem Mass Spectrometry - methods; pharmacokinetics; regadenoson, tandem mass spectrometry; hydrophilic interaction liquid chromatography