Principal Factors Associated With Ketorolac-Refractory Pain Behavior After Pediatric Myringotomy and Pressure Equalization Tube Placement: A Retrospective Cohort Study

• Published in: Anesthesia and analgesia Vol. 130; no. 3; pp. 730 - 739
• Main Authors: Cook-Sather, Scott D., Castella, Gabrielle, Zhang, Bingqing, Mensinger, Janell L., Galvez, Jorge, Wetmore, Ralph F.
• Format: Journal Article
• Language: English
• Published: United States International Anesthesia Research Society 01.03.2020
• Subjects: Age Factors; Anti-Inflammatory Agents, Non-Steroidal - administration & dosage; Anti-Inflammatory Agents, Non-Steroidal - adverse effects; Child Behavior; Child, Preschool; Drug Administration Schedule; Drug Resistance; Female; Hospitals, Pediatric; Humans; Infant; Ketorolac - administration & dosage; Ketorolac - adverse effects; Male; Middle Ear Ventilation - adverse effects; Pain Measurement; Pain, Postoperative - diagnosis; Pain, Postoperative - physiopathology; Pain, Postoperative - prevention & control; Pain, Postoperative - psychology; Philadelphia; Pressure; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome; Tympanic Membrane - surgery; Philadelphia

BACKGROUND:Prophylactic analgesic administration reduces pain behavior after pediatric bilateral myringotomy and pressure equalization tube placement (BMT). We hypothesized that postoperative pain in children treated with intraoperative ketorolac would, among several exposures of interest, be strong...