Monitoring of circulating amino acids in patients with pancreatic cancer and cancer cachexia using capillary electrophoresis and contactless conductivity detection

• Published in: Electrophoresis Vol. 42; no. 19; pp. 1885 - 1891
• Main Authors: Tůma, Petr, Hložek, Tomáš, Kamišová, Jana, Gojda, Jan
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.10.2021
• Subjects: Acetic acid; Acetonitrile; Alanine; Amino Acids; Amino Acids, Branched-Chain; Blood plasma; Branched chain amino acids; Cachexia; Cancer; Cancer cachexia; Capillary electrophoresis; Chain branching; Contactless conductivity detection; Electric Conductivity; electrolytes; Electrophoresis; Electrophoresis, Capillary; glucose tolerance tests; Glutamine; Humans; Insulin; methanol; Pancreatic cancer; Pancreatic Neoplasms; Plasma; Valine; Contactless conductivity detection; Cancer cachexia; Branched chain amino acids; Capillary electrophoresis; Insulin

Branched chain amino acids (BCAAs), alanine and glutamine are determined in human plasma by capillary electrophoresis with contactless conductivity detection (CE/C4D). The baseline separation of five amino acids from other plasma components is achieved on the short capillary effective length of 18 c...