A serum metabolomics‐driven approach predicts orange juice consumption and its impact on oxidative stress and inflammation in subjects from the BIONAOS study

• Published in: Molecular nutrition & food research Vol. 61; no. 2; pp. np - n/a
• Main Authors: Rangel‐Huerta, Oscar D., Aguilera, Concepcion M., Perez‐de‐la‐Cruz, Antonio, Vallejo, Fernando, Tomas‐Barberan, Francisco, Gil, Angel, Mesa, Maria D.
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.02.2017
• Subjects: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid - blood; Acids; Adult; Biomarkers; Biomarkers - blood; Citrus sinensis - chemistry; Consumption; Female; Flavanones; Fruit and Vegetable Juices; Gas Chromatography-Mass Spectrometry - methods; Humans; Hydroxyeicosatetraenoic Acids - blood; Inflammation; Inflammation - blood; Inflammation - diet therapy; Male; Metabolites; Metabolomics; Metabolomics - methods; Middle Aged; Multivariate statistical analysis; Orange juice; Oxidative Stress; Polyphenols; Polyphenols - pharmacology; Polyphenols - urine; Proline - analogs & derivatives; Proline - blood; Serum levels; Statistical analysis; Tandem Mass Spectrometry - methods; Young Adult; Flavanones; Metabolomics; Inflammation; Oxidative Stress; Orange juice

Scope To identify biomarkers of orange juice (OJ) consumption containing different doses of polyphenols and to determine its impact on oxidative stress and inflammation using an untargeted metabolomics analysis. Methods and results Thirty subjects aged 22–63 years from the BIONAOS study consumed a n...