The putative involvement of actin‐binding proteins and cytoskeleton proteins in pathological mechanisms of ketamine cystitis—Revealed by a prospective pilot study using proteomic approaches

• Published in: Proteomics. Clinical applications Vol. 11; no. 3-4; pp. np - n/a
• Main Authors: Yang, Hsueh‐Hui, Zhai, Wei‐Jun, Kuo, Hann‐Chorng
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.03.2017
• Subjects: Actins - metabolism; Adult; Apoptosis; Bioinformatics; Bladder; Cystitis; Cystitis - chemically induced; Cystitis - metabolism; Cytoskeletal Proteins - metabolism; Cytoskeleton; Female; Humans; Ketamine; Ketamine - adverse effects; Male; Middle Aged; Pilot Projects; Polypeptides; Prospective Studies; Proteins; Proteomics; Urinary bladder; Urinary bladder; Cystitis; Ketamine

Purpose Ketamine‐induced cystitis (KC) among chronic ketamine young abusers has increased dramatically and it has brought attention for Urologists. The underlying pathophysiological mechanism(s) of KC is still unclear. Therefore, the purpose of this study is to elucidate the possible pathophysiologi...