Fluoxetine in the acute treatment and relapse prevention of combat-related post-traumatic stress disorder: Analysis of the veteran group of a placebo-controlled, randomized clinical trial

• Published in: European neuropsychopharmacology Vol. 16; no. 5; pp. 340 - 349
• Main Authors: Martenyi, Ferenc, Soldatenkova, Victoria
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2006
• Subjects: Acute treatment; Adult; Aged; Antidepressive Agents, Second-Generation - therapeutic use; Combat-related PTSD; Double-Blind Method; Female; Fluoxetine; Fluoxetine - therapeutic use; Humans; Male; Middle Aged; Placebo; Psychiatric Status Rating Scales; Relapse prevention; Secondary Prevention; Stress Disorders, Post-Traumatic - drug therapy; Stress Disorders, Post-Traumatic - psychology; Survival Analysis; Treatment Outcome; Veterans - psychology; Yugoslavia; Yugoslavia; Acute treatment; Combat-related PTSD; Fluoxetine; Relapse prevention; Placebo

The efficacy and safety of fluoxetine (20–80 mg) was compared with placebo in 144 veterans [36.2 years], diagnosed with combat-related post-traumatic stress disorder (PTSD) selected from a 12-week acute and 24-week relapse prevention PTSD trial. In the acute phase, improvements were greater with flu...