RNA analysis of tape strips to rule out melanoma in lesions clinically assessed as cutaneous malignant melanoma: A diagnostic study

• Published in: Journal of the American Academy of Dermatology Vol. 89; no. 3; pp. 537 - 543
• Main Authors: Heerfordt, Ida M., Philipsen, Peter A., Andersen, Jeppe D., Langhans, Linnea, Schmidt, Grethe, Morling, Niels, Wulf, Hans Christian
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2023
• Subjects: Antigens, Neoplasm; COVID-19; COVID-19 Testing; diagnostic tool; gene expression; Humans; melanoma; Melanoma - diagnosis; Melanoma - genetics; Melanoma - pathology; Melanoma, Cutaneous Malignant; nevi; Nevus - diagnosis; Nevus - genetics; noninvasive; PRAME; RNA; Skin Neoplasms - diagnosis; Skin Neoplasms - genetics; Skin Neoplasms - surgery; CMM; BCC; PLA; RNA; SRC; melanoma; Ct; noninvasive; diagnostic tool; KIT; nevi; PRAME; gene expression

Distinguishing cutaneous malignant melanoma (CMM) from nevi can be clinically challenging. Suspicious lesions are therefore excised, resulting in many benign lesions being removed surgically to find 1 CMM. It has been proposed to use tape strip derived ribonucleic acid (RNA) to distinguish CMM from...