The Prevalence and Genetic Diversity of PCV3 and PCV2 in Colombia and PCV4 Survey during 2015–2016 and 2018–2019
Four genotypes of circovirus have been recognized in swine, with PCV2 and PCV3 being the most associated with clinical manifestations, while PCV4 does not have a defined disease. In addition, PCV2 is associated with different syndromes grouped as diseases associated with porcine circovirus (PCVAD),...
Saved in:
| Published in | Pathogens (Basel) Vol. 11; no. 6; p. 633 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Basel
MDPI AG
31.05.2022
MDPI |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Four genotypes of circovirus have been recognized in swine, with PCV2 and PCV3 being the most associated with clinical manifestations, while PCV4 does not have a defined disease. In addition, PCV2 is associated with different syndromes grouped as diseases associated with porcine circovirus (PCVAD), while PCV3 causes systemic and reproductive diseases. In the present study, we retrospectively detected PCV2, PCV3, and PCV4 in Colombia during two periods: A (2015–2016) and B (2018–2019). During period A, we evaluated stool pools from the 32 Colombian provinces, finding a higher prevalence of PCV3 compared to PCV2 as well as PCV2/PCV3 co-infection. Furthermore, we determined that PCV3 had been circulating since 2015 in Colombia. Regarding period B, we evaluated sera pools and tissues from abortions and stillborn piglets from the five provinces with the highest pig production. The highest prevalence found was for PCV3 in tissues followed by sera pools, while PCV2 was lower and only in sera pools. In addition, PCV2/PCV3 co-infection in sera pools was also found for this period. The complete genome sequences of PCV3 and PCV3-ORF2 placed the Colombian isolates within clade 1 as the majority in the world. For PCV2, the predominant genotype currently in Colombia is PCV2d. Likewise, in some PCV3-ORF2 sequences, a mutation (A24V) was found at the level of the Cap protein, which could be involved in PCV3 immunogenic recognition. Regarding PCV4, retrospective surveillance showed that there is no evidence of the presence of this virus in Colombia. |
|---|---|
| AbstractList | Four genotypes of circovirus have been recognized in swine, with PCV2 and PCV3 being the most associated with clinical manifestations, while PCV4 does not have a defined disease. In addition, PCV2 is associated with different syndromes grouped as diseases associated with porcine circovirus (PCVAD), while PCV3 causes systemic and reproductive diseases. In the present study, we retrospectively detected PCV2, PCV3, and PCV4 in Colombia during two periods: A (2015–2016) and B (2018–2019). During period A, we evaluated stool pools from the 32 Colombian provinces, finding a higher prevalence of PCV3 compared to PCV2 as well as PCV2/PCV3 co-infection. Furthermore, we determined that PCV3 had been circulating since 2015 in Colombia. Regarding period B, we evaluated sera pools and tissues from abortions and stillborn piglets from the five provinces with the highest pig production. The highest prevalence found was for PCV3 in tissues followed by sera pools, while PCV2 was lower and only in sera pools. In addition, PCV2/PCV3 co-infection in sera pools was also found for this period. The complete genome sequences of PCV3 and PCV3-ORF2 placed the Colombian isolates within clade 1 as the majority in the world. For PCV2, the predominant genotype currently in Colombia is PCV2d. Likewise, in some PCV3-ORF2 sequences, a mutation (A24V) was found at the level of the Cap protein, which could be involved in PCV3 immunogenic recognition. Regarding PCV4, retrospective surveillance showed that there is no evidence of the presence of this virus in Colombia. |
| Author | Jaime, Jairo Vargas-Bermudez, Diana S Mogollón, José Darío |
| AuthorAffiliation | Universidad Nacional de Colombia, Sede Bogotá, Facultad de Medicina Veterinaria y de Zootecnia, Departamento de Salud Animal, Centro de Investigación en Infectología e Inmunología Veterinaria (CI3V), Carrera 30 No. 45-03, Bogotá CP 111321, Colombia; dsvargasb@unal.edu.co (D.S.V.-B.); josedmogollon@yahoo.es (J.D.M.) |
| AuthorAffiliation_xml | – name: Universidad Nacional de Colombia, Sede Bogotá, Facultad de Medicina Veterinaria y de Zootecnia, Departamento de Salud Animal, Centro de Investigación en Infectología e Inmunología Veterinaria (CI3V), Carrera 30 No. 45-03, Bogotá CP 111321, Colombia; dsvargasb@unal.edu.co (D.S.V.-B.); josedmogollon@yahoo.es (J.D.M.) |
| Author_xml | – sequence: 1 givenname: Diana S. surname: Vargas-Bermudez fullname: Vargas-Bermudez, Diana S. – sequence: 2 givenname: José Darío surname: Mogollón fullname: Mogollón, José Darío – sequence: 3 givenname: Jairo orcidid: 0000-0001-7697-5101 surname: Jaime fullname: Jaime, Jairo |
| BookMark | eNplks1uEzEQxy1UREvpA3CzxIVLwPZ4be8FCQVaKlWiEoWr5V3PJhtt7GDvRsqNd-AN-yQ4SUEU5jJff_00M5rn5CTEgIS85OwNQM3ebty4jAsMmXOmmAJ4Qs4E02rGDNcnf8Wn5CLnFStm2D5_Rk6h0rKSRp-R8W6J9Dbh1g0YWqQueHqFAce-pR_6LabcjzsaO3o7_waHbgkE7QOdxyGum979Lkr6ZUpb3FE_pT4sqGC8uv_xszh1kJTAHPP6BXnauSHjxYM_J18vP97NP81uPl9dz9_fzFrJ2DhrwTglFKL0lRBaKdM52YF02LRKGI3gucZOcCgi1mLZyAB4x7lveIUA5-T6yPXRrewm9WuXdja63h4KMS2sS2XTAa035RzgmWiElsJ0DUpoagZeyrpqgBfWuyNrMzVr9C2GMbnhEfRxJ_RLu4hbWwthpNIF8PoBkOL3CfNo131ucRhcwDhlK5ThDKRm-7lf_SNdxSmFcqqi0rVhRlZ7FT-q2hRzTtj9GYYzu38R-9-LwC-Cw639 |
| CitedBy_id | crossref_primary_10_1038_s41598_023_32382_1 crossref_primary_10_3390_v14081799 crossref_primary_10_1007_s13337_023_00849_4 crossref_primary_10_1371_journal_pone_0293135 crossref_primary_10_3390_vetsci11060264 crossref_primary_10_3389_fmicb_2023_1121177 crossref_primary_10_1038_s41598_024_66328_y crossref_primary_10_1080_01652176_2023_2234430 crossref_primary_10_3389_fmicb_2023_1258484 crossref_primary_10_3389_fmicb_2022_1052533 crossref_primary_10_14405_kjvr_20220039 crossref_primary_10_3390_pathogens12020250 crossref_primary_10_1186_s12985_023_02181_1 crossref_primary_10_3389_fmicb_2024_1385137 |
| Cites_doi | 10.1111/tbed.12702 10.1111/tbed.13714 10.1016/j.virusres.2016.02.010 10.1111/tbed.12853 10.3390/v12030265 10.1007/s00705-021-05088-w 10.1136/vr.162.26.867 10.1371/journal.pone.0208585 10.1111/tbed.12735 10.1016/j.vetmic.2018.01.004 10.1016/j.gene.2020.145384 10.3390/pathogens10050585 10.1111/tbed.13446 10.1007/s00705-019-04336-4 10.1111/tbed.13893 10.1128/JVI.01879-16 10.1016/j.vetmic.2012.12.033 10.1111/tbed.12836 10.1093/nar/gkx932 10.12688/f1000research.13160.2 10.1111/tbed.12667 10.1002/advs.201800275 10.3390/v11121135 10.3390/v12020219 10.1186/s12879-019-4398-0 10.1111/tbed.14204 10.1016/j.micpath.2020.104047 10.1016/j.tvjl.2005.04.013 10.1111/tbed.14017 10.1007/BF01314286 10.1093/molbev/msw054 10.1111/tbed.12752 10.1186/s12985-018-0929-3 10.3390/pathogens9060433 10.1186/s12985-016-0642-z 10.1002/vms3.155 10.1002/advs.201901004 10.1111/tbed.13467 10.2478/v10181-011-0111-y 10.1128/JVI.02045-18 10.1186/s12917-021-02862-5 10.1016/j.vetmic.2012.02.010 10.1186/1743-422X-11-143 10.1111/tbed.12721 10.1101/2020.06.07.138925 10.1016/j.vetmic.2016.11.009 10.1007/s11262-018-1553-4 10.1016/j.ympev.2016.04.028 10.1186/s13567-016-0405-2 10.1016/j.vetmic.2016.05.002 10.1111/tbed.13833 10.1016/j.vetmic.2017.06.013 10.4142/jvs.2018.19.5.721 10.1186/s12985-017-0892-4 10.1016/j.meegid.2018.12.011 10.1111/tbed.13341 10.1016/j.virusres.2011.09.014 10.1111/tbed.12876 10.1186/1743-422X-7-273 |
| ContentType | Journal Article |
| Copyright | 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2022 by the authors. 2022 |
| Copyright_xml | – notice: 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2022 by the authors. 2022 |
| DBID | AAYXX CITATION 7T7 8FD 8FE 8FH ABUWG AFKRA AZQEC BBNVY BENPR BHPHI C1K CCPQU DWQXO FR3 GNUQQ HCIFZ LK8 M7P P64 PIMPY PQEST PQQKQ PQUKI PRINS 7X8 5PM DOA |
| DOI | 10.3390/pathogens11060633 |
| DatabaseName | CrossRef Industrial and Applied Microbiology Abstracts (Microbiology A) Technology Research Database ProQuest SciTech Collection ProQuest Natural Science Collection ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Collection AUTh Library subscriptions: ProQuest Central ProQuest Natural Science Collection Environmental Sciences and Pollution Management ProQuest One Community College ProQuest Central Engineering Research Database ProQuest Central Student SciTech Premium Collection (Proquest) (PQ_SDU_P3) Biological Sciences Biological Science Database Biotechnology and BioEngineering Abstracts Publicly Available Content Database ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) DAOJ: Directory of Open Access Journals |
| DatabaseTitle | CrossRef Publicly Available Content Database ProQuest Central Student Technology Research Database ProQuest Biological Science Collection ProQuest Central Essentials ProQuest One Academic Eastern Edition ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest Natural Science Collection Biological Science Database ProQuest SciTech Collection ProQuest Central China Biotechnology and BioEngineering Abstracts Environmental Sciences and Pollution Management ProQuest Central ProQuest One Academic UKI Edition Natural Science Collection ProQuest Central Korea Biological Science Collection Engineering Research Database Industrial and Applied Microbiology Abstracts (Microbiology A) ProQuest One Academic MEDLINE - Academic |
| DatabaseTitleList | Publicly Available Content Database CrossRef |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: BENPR name: AUTh Library subscriptions: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology |
| EISSN | 2076-0817 |
| ExternalDocumentID | oai_doaj_org_article_d84873d02b27428fbe43b903d4495b31 10_3390_pathogens11060633 |
| GeographicLocations | Colombia United States--US China |
| GeographicLocations_xml | – name: Colombia – name: China – name: United States--US |
| GrantInformation_xml | – fundername: Universidad Nacional de Colombia, Facultad de Medicina Veterinaria y de Zootecnia grantid: 48508; 45486 – fundername: Asociación Colombiana de Porcicultores–PorkColombia (PEDV Project—2016) |
| GroupedDBID | 53G 5VS 8FE 8FH AADQD AAHBH AAYXX ADBBV AFKRA AFZYC ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BBNVY BCNDV BENPR BHPHI CCPQU CITATION DIK GROUPED_DOAJ HCIFZ HYE IAO IHR ITC KQ8 LK8 M48 M7P MODMG M~E OK1 PGMZT PIMPY PROAC RIG RPM 7T7 8FD ABUWG AZQEC C1K DWQXO FR3 GNUQQ P64 PQEST PQQKQ PQUKI PRINS 7X8 5PM |
| ID | FETCH-LOGICAL-c400t-c38a626ee4d5227668fa4f34aebc6287e3d17ef21326e0ce548833da11db15e33 |
| IEDL.DBID | RPM |
| ISSN | 2076-0817 |
| IngestDate | Fri Oct 04 13:12:29 EDT 2024 Tue Sep 17 21:26:46 EDT 2024 Sat Oct 05 05:28:11 EDT 2024 Wed Sep 25 01:00:55 EDT 2024 Thu Sep 26 21:04:10 EDT 2024 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Language | English |
| License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c400t-c38a626ee4d5227668fa4f34aebc6287e3d17ef21326e0ce548833da11db15e33 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ORCID | 0000-0001-7697-5101 |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228467/ |
| PMID | 35745487 |
| PQID | 2679808453 |
| PQPubID | 2032351 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_d84873d02b27428fbe43b903d4495b31 pubmedcentral_primary_oai_pubmedcentral_nih_gov_9228467 proquest_miscellaneous_2681034703 proquest_journals_2679808453 crossref_primary_10_3390_pathogens11060633 |
| PublicationCentury | 2000 |
| PublicationDate | 20220531 |
| PublicationDateYYYYMMDD | 2022-05-31 |
| PublicationDate_xml | – month: 5 year: 2022 text: 20220531 day: 31 |
| PublicationDecade | 2020 |
| PublicationPlace | Basel |
| PublicationPlace_xml | – name: Basel |
| PublicationTitle | Pathogens (Basel) |
| PublicationYear | 2022 |
| Publisher | MDPI AG MDPI |
| Publisher_xml | – name: MDPI AG – name: MDPI |
| References | Tochetto (ref_19) 2018; 65 Monroy (ref_45) 2014; 11 Jiang (ref_50) 2019; 93 Zhai (ref_28) 2017; 14 Hou (ref_57) 2021; 68 Tischer (ref_3) 1986; 91 Campos (ref_20) 2019; 5 ref_58 Kumar (ref_61) 2016; 33 Guo (ref_6) 2010; 7 Franzo (ref_11) 2016; 100 Ellis (ref_4) 1998; 39 Guo (ref_34) 2020; 142 Xiao (ref_46) 2016; 197 ref_18 Ha (ref_54) 2021; 166 ref_59 Kim (ref_25) 2018; 19 Pejsak (ref_48) 2012; 15 Opriessnig (ref_36) 2012; 158 Mateu (ref_44) 2006; 171 Klaumann (ref_16) 2018; 65 Saporiti (ref_42) 2020; 67 Palinski (ref_13) 2017; 91 Serena (ref_22) 2020; 68 Merdy (ref_60) 2016; 47 ref_21 Phan (ref_12) 2016; 13 Opriessnig (ref_37) 2012; 164 Franzo (ref_17) 2018; 65 Zheng (ref_23) 2017; 64 ref_29 Jaime (ref_49) 2018; 7 Chen (ref_55) 2020; 68 Li (ref_51) 2018; 5 Olvera (ref_5) 2008; 162 Dvorak (ref_43) 2016; 189 Kekarainen (ref_10) 2013; 165 Chen (ref_35) 2019; 68 Davies (ref_7) 2016; 217 ref_30 Fux (ref_40) 2018; 15 Sun (ref_52) 2021; 773 Kedkovid (ref_26) 2018; 215 Nguyen (ref_56) 2021; 69 Ye (ref_14) 2018; 54 Kwon (ref_24) 2017; 207 Bao (ref_8) 2018; 65 ref_47 Sun (ref_15) 2018; 65 Chen (ref_27) 2017; 64 Wang (ref_32) 2020; 67 ref_41 Lefkowitz (ref_1) 2018; 46 Tian (ref_53) 2021; 68 Fu (ref_39) 2018; 65 ref_9 Xia (ref_33) 2019; 164 Zhang (ref_2) 2020; 67 Saporiti (ref_31) 2021; 68 Franzo (ref_38) 2019; 6 |
| References_xml | – volume: 64 start-page: 1650 year: 2017 ident: ref_27 article-title: Detection and genome sequencing of porcine circovirus 3 in neonatal pigs with congenital tremors in South China publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.12702 contributor: fullname: Chen – volume: 68 start-page: 276 year: 2021 ident: ref_53 article-title: Molecular detection and phylogenetic analysis of Porcine circovirus 4 in Henan and Shanxi Provinces of China publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.13714 contributor: fullname: Tian – volume: 217 start-page: 32 year: 2016 ident: ref_7 article-title: Diagnostic phylogenetics reveals a new Porcine circovirus 2 cluster publication-title: Virus Res. doi: 10.1016/j.virusres.2016.02.010 contributor: fullname: Davies – volume: 65 start-page: 607 year: 2018 ident: ref_15 article-title: Retrospective study of porcine circovirus 3 infection in China publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.12853 contributor: fullname: Sun – ident: ref_41 doi: 10.3390/v12030265 – volume: 166 start-page: 1951 year: 2021 ident: ref_54 article-title: Retrospective surveillance of porcine circovirus 4 in pigs in Inner Mongolia, China, from 2016 to 2018 publication-title: Arch. Virol. doi: 10.1007/s00705-021-05088-w contributor: fullname: Ha – volume: 162 start-page: 867 year: 2008 ident: ref_5 article-title: PCV-2 genotype definition and nomenclature publication-title: Vet. Rec. doi: 10.1136/vr.162.26.867 contributor: fullname: Olvera – ident: ref_9 doi: 10.1371/journal.pone.0208585 – volume: 65 start-page: 5 year: 2018 ident: ref_19 article-title: Full-Genome Sequence of Porcine Circovirus type 3 recovered from serum of sows with stillbirths in Brazil publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.12735 contributor: fullname: Tochetto – volume: 215 start-page: 71 year: 2018 ident: ref_26 article-title: Porcine circovirus type 3 (PCV3) infection in grower pigs from a Thai farm suffering from porcine respiratory disease complex (PRDC) publication-title: Vet. Microbiol. doi: 10.1016/j.vetmic.2018.01.004 contributor: fullname: Kedkovid – volume: 773 start-page: 145384 year: 2021 ident: ref_52 article-title: Detection and genetic characterization of porcine circovirus 4 (PCV4) in Guangxi, China publication-title: Gene doi: 10.1016/j.gene.2020.145384 contributor: fullname: Sun – ident: ref_18 doi: 10.3390/pathogens10050585 – volume: 67 start-page: 1057 year: 2020 ident: ref_2 article-title: Novel circovirus species identified in farmed pigs designated as Porcine circovirus 4, Hunan province, China publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.13446 contributor: fullname: Zhang – volume: 164 start-page: 2435 year: 2019 ident: ref_33 article-title: The prevalence and genetic diversity of porcine circovirus types 2 and 3 in Northeast China from 2015 to 2018 publication-title: Arch. Virol. doi: 10.1007/s00705-019-04336-4 contributor: fullname: Xia – volume: 68 start-page: 1761 year: 2020 ident: ref_22 article-title: First detection and genetic characterization of porcine circovirus type 3 (PCV3) in Argentina and its association with reproductive failure publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.13893 contributor: fullname: Serena – volume: 91 start-page: e01879-16 year: 2017 ident: ref_13 article-title: A Novel Porcine Circovirus Distantly Related to Known Circoviruses Is Associated with Porcine Dermatitis and Nephropathy Syndrome and Reproductive Failure publication-title: J. Virol. doi: 10.1128/JVI.01879-16 contributor: fullname: Palinski – volume: 165 start-page: 13 year: 2013 ident: ref_10 article-title: The natural history of porcine circovirus type 2: From an inoffensive virus to a devastating swine disease? publication-title: Vet. Microbiol. doi: 10.1016/j.vetmic.2012.12.033 contributor: fullname: Kekarainen – volume: 65 start-page: 602 year: 2018 ident: ref_17 article-title: Full-genome sequencing of porcine circovirus 3 field strains from Denmark, Italy and Spain demonstrates a high within-Europe genetic heterogeneity publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.12836 contributor: fullname: Franzo – volume: 46 start-page: D708 year: 2018 ident: ref_1 article-title: Virus taxonomy: The database of the International Committee on Taxonomy of Viruses (ICTV) publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkx932 contributor: fullname: Lefkowitz – volume: 7 start-page: 42 year: 2018 ident: ref_49 article-title: Longitudinal comparison of the humoral immune response and viral load of Porcine Circovirus Type 2 in pigs with different vaccination schemes under field conditions publication-title: F1000Research doi: 10.12688/f1000research.13160.2 contributor: fullname: Jaime – volume: 64 start-page: 1337 year: 2017 ident: ref_23 article-title: The occurrence of porcine circovirus 3 without clinical infection signs in Shandong Province publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.12667 contributor: fullname: Zheng – volume: 5 start-page: 1800275 year: 2018 ident: ref_51 article-title: Origin, genetic diversity, and evolutionary dynamics of novel porcine circovirus 3 publication-title: Adv. Sci. doi: 10.1002/advs.201800275 contributor: fullname: Li – ident: ref_47 doi: 10.3390/v11121135 – ident: ref_29 doi: 10.3390/v12020219 – ident: ref_59 doi: 10.1186/s12879-019-4398-0 – volume: 68 start-page: 2936 year: 2021 ident: ref_31 article-title: Porcine circovirus 3 (PCV-3) as a causal agent of disease in swine and a proposal of PCV-3 associated disease case definition publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.14204 contributor: fullname: Saporiti – volume: 142 start-page: 104047 year: 2020 ident: ref_34 article-title: Co-infection status of porcine circoviruses (PCV2 and PCV3) and porcine epidemic diarrhea virus (PEDV) in pigs with watery diarrhea in Henan province, central China publication-title: Microb. Pathog. doi: 10.1016/j.micpath.2020.104047 contributor: fullname: Guo – volume: 171 start-page: 396 year: 2006 ident: ref_44 article-title: Immunosuppression as a feature of postweaning multisystemic wasting syndrome publication-title: Vet. J. doi: 10.1016/j.tvjl.2005.04.013 contributor: fullname: Mateu – volume: 68 start-page: 1 year: 2021 ident: ref_57 article-title: Phylogenetic analysis of porcine circoviruses 4 in Henan Province of China: A retrospective study from 2011 to 2021 publication-title: Transbound. Emerg. Dis. contributor: fullname: Hou – volume: 69 start-page: 538 year: 2021 ident: ref_56 article-title: Molecular based detection, genetic characterization and phylogenetic analysis of porcine circovirus 4 from Korean domestic swine farms publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.14017 contributor: fullname: Nguyen – volume: 91 start-page: 271 year: 1986 ident: ref_3 article-title: Studies on epidemiology and pathogenicity of porcine circovirus publication-title: Arch. Virol. doi: 10.1007/BF01314286 contributor: fullname: Tischer – volume: 33 start-page: 1870 year: 2016 ident: ref_61 article-title: MEGA7: Molecular evolutionary genetics analysis version 7.0 for bigger datasets publication-title: Mol. Biol. Evol. doi: 10.1093/molbev/msw054 contributor: fullname: Kumar – volume: 65 start-page: e296 year: 2018 ident: ref_39 article-title: Insights into the epidemic characteristics and evolutionary history of the novel porcine circovirus type 3 in southern China publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.12752 contributor: fullname: Fu – volume: 15 start-page: 25 year: 2018 ident: ref_40 article-title: Full genome characterization of porcine circovirus type 3 isolates reveals the existence of two distinct groups of virus strains publication-title: Virol. J. doi: 10.1186/s12985-018-0929-3 contributor: fullname: Fux – ident: ref_58 doi: 10.3390/pathogens9060433 – volume: 13 start-page: 184 year: 2016 ident: ref_12 article-title: Detection of a novel circovirus PCV3 in pigs with cardiac and multi-systemic inflammation publication-title: Virol. J. doi: 10.1186/s12985-016-0642-z contributor: fullname: Phan – volume: 5 start-page: 182 year: 2019 ident: ref_20 article-title: First detection of porcine circovirus type 3 in Colombia and the complete genome sequence demonstrates the circulation of PCV3a1 and PCV3a2 publication-title: Vet. Med. Sci. doi: 10.1002/vms3.155 contributor: fullname: Campos – volume: 6 start-page: 1901004 year: 2019 ident: ref_38 article-title: A Shift in Porcine Circovirus 3 (PCV-3) History Paradigm: Phylodynamic Analyses Reveal an Ancient Origin and Prolonged Undetected Circulation in the Worldwide Swine Population publication-title: Adv. Sci. doi: 10.1002/advs.201901004 contributor: fullname: Franzo – volume: 67 start-page: 1284 year: 2020 ident: ref_32 article-title: Genetic diversity and prevalence of porcine circovirus type 3 (PCV3) and type 2 (PCV2) in the Midwest of the USA during 2016-2018 publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.13467 contributor: fullname: Wang – volume: 15 start-page: 37 year: 2012 ident: ref_48 article-title: Influence of long-term vaccination of a breeding herd of pigs against PCV2 on reproductive parameters publication-title: Pol. J. Vet. Sci. doi: 10.2478/v10181-011-0111-y contributor: fullname: Pejsak – volume: 93 start-page: e02045-18 year: 2019 ident: ref_50 article-title: Induction of Porcine Dermatitis and Nephropathy Syndrome in Piglets by Infection with Porcine Circovirus Type 3 publication-title: J. Virol. doi: 10.1128/JVI.02045-18 contributor: fullname: Jiang – ident: ref_30 doi: 10.1186/s12917-021-02862-5 – volume: 158 start-page: 69 year: 2012 ident: ref_36 article-title: Effect of porcine circovirus type 2a or 2b on infection kinetics and pathogenicity of two genetically divergent strains of porcine reproductive and respiratory syndrome virus in the conventional pig model publication-title: Vet. Microbiol. doi: 10.1016/j.vetmic.2012.02.010 contributor: fullname: Opriessnig – volume: 11 start-page: 143 year: 2014 ident: ref_45 article-title: Detection and molecular characterization of porcine circovirus type 2 from piglets with porcine circovirus associated diseases in Colombia publication-title: Virol. J. doi: 10.1186/1743-422X-11-143 contributor: fullname: Monroy – volume: 65 start-page: 432 year: 2018 ident: ref_8 article-title: Retrospective study of porcine circovirus type 2 infection reveals a novel genotype PCV2f publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.12721 contributor: fullname: Bao – ident: ref_21 doi: 10.1101/2020.06.07.138925 – volume: 197 start-page: 72 year: 2016 ident: ref_46 article-title: PCV2d-2 is the predominant type of PCV2 DNA in pig samples collected in the U.S. during 2014-2016 publication-title: Vet. Microbiol. doi: 10.1016/j.vetmic.2016.11.009 contributor: fullname: Xiao – volume: 54 start-page: 466 year: 2018 ident: ref_14 article-title: Detection and genetic characterisation of porcine circovirus 3 from pigs in Sweden publication-title: Virus Genes doi: 10.1007/s11262-018-1553-4 contributor: fullname: Ye – volume: 100 start-page: 269 year: 2016 ident: ref_11 article-title: Phylodynamic analysis of porcine circovirus type 2 reveals global waves of emerging genotypes and the circulation of recombinant forms publication-title: Mol. Phylogenet. Evol. doi: 10.1016/j.ympev.2016.04.028 contributor: fullname: Franzo – volume: 47 start-page: 121 year: 2016 ident: ref_60 article-title: Evaluation of natural porcine circovirus type 2 (PCV2) subclinical infection and seroconversion dynamics in piglets vaccinated at different ages publication-title: Vet. Res. doi: 10.1186/s13567-016-0405-2 contributor: fullname: Merdy – volume: 189 start-page: 86 year: 2016 ident: ref_43 article-title: National reduction in porcine circovirus type 2 prevalence following introduction of vaccination publication-title: Vet. Microbiol. doi: 10.1016/j.vetmic.2016.05.002 contributor: fullname: Dvorak – volume: 68 start-page: 1615 year: 2020 ident: ref_55 article-title: Development and application of a quadruplex real-time PCR assay for differential detection of porcine circoviruses (PCV1 to PCV4) in Jiangsu province of China from 2016 to 2020 publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.13833 contributor: fullname: Chen – volume: 207 start-page: 178 year: 2017 ident: ref_24 article-title: Prevalence of novel porcine circovirus 3 in Korean pig populations publication-title: Vet. Microbiol. doi: 10.1016/j.vetmic.2017.06.013 contributor: fullname: Kwon – volume: 19 start-page: 721 year: 2018 ident: ref_25 article-title: Detection and genetic characterization of porcine circovirus 3 from aborted fetuses and pigs with respiratory disease in Korea publication-title: J. Vet. Sci. doi: 10.4142/jvs.2018.19.5.721 contributor: fullname: Kim – volume: 14 start-page: 222 year: 2017 ident: ref_28 article-title: Comparative epidemiology of porcine circovirus type 3 in pigs with different clinical presentations publication-title: Virol. J. doi: 10.1186/s12985-017-0892-4 contributor: fullname: Zhai – volume: 68 start-page: 127 year: 2019 ident: ref_35 article-title: Co-infection status of classical swine fever virus (CSFV), porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circoviruses (PCV2 and PCV3) in eight regions of China from 2016 to 2018 publication-title: Infect. Genet. Evol. doi: 10.1016/j.meegid.2018.12.011 contributor: fullname: Chen – volume: 67 start-page: 199 year: 2020 ident: ref_42 article-title: Similar frequency of Porcine circovirus 3 (PCV-3) detection in serum samples of pigs affected by digestive or respiratory disorders and age-matched clinically healthy pigs publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.13341 contributor: fullname: Saporiti – volume: 39 start-page: 44 year: 1998 ident: ref_4 article-title: Isolation of circovirus from lesions of pigs with postweaning multisystemic wasting syndrome publication-title: Can. Vet. J. contributor: fullname: Ellis – volume: 164 start-page: 20 year: 2012 ident: ref_37 article-title: Concurrent infections are important for expression of porcine circovirus associated disease publication-title: Virus Res. doi: 10.1016/j.virusres.2011.09.014 contributor: fullname: Opriessnig – volume: 65 start-page: 1290 year: 2018 ident: ref_16 article-title: Retrospective detection of Porcine circovirus 3 (PCV-3) in pig serum samples from Spain publication-title: Transbound. Emerg. Dis. doi: 10.1111/tbed.12876 contributor: fullname: Klaumann – volume: 7 start-page: 273 year: 2010 ident: ref_6 article-title: Porcine circovirus type 2 (PCV2): Genetic variation and newly emerging genotypes in China publication-title: Virol. J. doi: 10.1186/1743-422X-7-273 contributor: fullname: Guo |
| SSID | ssj0000800817 |
| Score | 2.3100386 |
| Snippet | Four genotypes of circovirus have been recognized in swine, with PCV2 and PCV3 being the most associated with clinical manifestations, while PCV4 does not have... |
| SourceID | doaj pubmedcentral proquest crossref |
| SourceType | Open Website Open Access Repository Aggregation Database |
| StartPage | 633 |
| SubjectTerms | Classification Epidemics Fetuses Gene sequencing Genetic diversity Genomes Genotypes Hogs Immunogenicity Infections Mutation ORF2 PCV2 PCV3 PCV4 Phylogenetics porcine circovirus-PCVs prevalence Provinces Swine Swine production Viruses |
| SummonAdditionalLinks | – databaseName: DAOJ: Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3NSsQwEA4iCF7EX1z_iOBJKLaZtM0edXURQRF0xVtJmimuYFd0V_DmO_iGPomTpCtbPHjx1DQJbTrTdL6vM5kwdlBa_9UXkf__JrXKImOxjCRZJxsD5mnlFgpfXmXnA3lxn97PbPXlYsJCeuAguCOrCFKDjYVxTkVVGZRgujFYSdDeQCA-STpDph4bHKSSPLgxgXi9i69-GJFOXsneEWgHaBkin6-_BTLbIZIzNqe_zJYasMiPwyBX2BzWq2whbB_5vsbGpGPucjBpv3KI69pyl0aaevPTabwFH1X8uncHvpUKgg9r3qMrPJmhnlZKfjN5ecN3HlYtchJp-vXxSYfMd6GCCufddTbon932zqNmF4WopPk5jkpQmlgLorSEtfIsU5WWFUiNpsyILyHYJMdKEC3NMC6RKIwCsDpJrElSBNhg8_Woxk3GSQ9lIqyRqTGSLF8XCd85zpZVZUy4q8MOpyItnkOyjIJIhpN_8Uv-HXbihP7T0eW59hWk_aLRfvGX9jtsZ6qyopl8r4VwnqVYyZTusf_TTNPG-UJ0jaOJ66OSGCR97zosb6m6NaB2Sz188Am4u0I42Lb1H0-wzRaFW1HhAxJ22Pz4ZYK7hHPGZs-_0t8f9fkI priority: 102 providerName: Directory of Open Access Journals – databaseName: AUTh Library subscriptions: ProQuest Central dbid: BENPR link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELZKKyQuiKcILchInJCijT1O4j0hurRaIVFVQFFvkV-he2hStlmk3vof-If8EmacZCFC4pSHrSSaiT3f53mYsdfOx1lfpnH9TRldpNYHlyq0Tj6DUOY1JQp_PCmWZ-rDeX6-w5ZjLgyFVY5zYpyofetojXwmyV2QaZXDzFhaBXDd7O3V95T2jyI_67CZxh22J4Uih-3e4dHJ6aftegshIy3K3rEJyPQp4vqiRS1dowVEGA8wMU2xgv8Edk6DJv-yQscP2P0BPvJ3vb4fsp3QPGJ3-w0lbx6zDrXOqSqTiblE3DSeU2Fp7M3fjxEYvK356eIrxFY8kXzV8AU-4dKuzHhT8c-b9Y9ww_s8Ro5Czn_d_sRDEbvgie6v50_Y2fHRl8UyHfZVSB2O2C51oA3ymBCUR_RVFoWujapBmWBdgQwqgBdlqCUS1SJkLiCp0QDeCOGtyAPAU7bbtE14xngJ3gnprcqtVWgL5wERH7G4onYZIrGEvRlFWl315TMqpB0k_-of-SfskIS-7UiVr-ONdv2tGgZS5TVSLPCZtORk1rUNCuw8A6-Q6lkQCTsYVVYNw_G6-vPzJOzVthkHEnlHTBPaDfXRIgOFM2DCyomqJx80bWlWF7Ek91xKAnLP___yfXZPUvZEDD44YLvdehNeIKbp7Mvhd_0N2Jb2wA priority: 102 providerName: ProQuest – databaseName: Scholars Portal Journals: Open Access dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3fi9QwEB7OE8EX8SeunhLBJ6HSZtI2-yCiq8chnAi6cm8laabeHtqee7vi_vfOpO1h8R58C0lIy2Sm831NZgbgeR3iV18n8f-bcbZIfKA6MeydQopU5o0ECh9_LI6W5sNJfrIHY3mrQYAXV1I7qSe1XH9_-fvn7jUb_CthnEzZ5er0acfivmBXxngc8Rpc1waNKPzxgPbPBnBkYw1ezew9kXZ_znn1KhNPFRP6T1Do9A7lX07p8DbcGtCketNv_x3Yo_Yu3OjrS-7uwTkrgZIkTS6GFinXBiV5pnm2ejdeyFBdoz4tvmIc5YZWq1YteIUffuXGTqM-b9e_aKf6sEbFMs9F8EWcwA0xhGx-H5aH778sjpKhxEJSs_FukhqtY0pDZAIDsbIobONMg8aRrwsmU4QhK6nRzFkLSmtifmMRg8uy4LOcEB_Aftu19BBUiaHOdPAm996wW5wTgz8hdEVTpwzKZvBiFGd13mfSqJiBiOyrf2Q_g7ci8MuJkgQ7dnTrb9VgU1WwzLYwpNrLebNtPBn08xSDYdbnMZvBwbhd1ahYlZZjp9SanJ_x7HKYbUoOSlxL3Vbm2CxFwx_DGZSTbZ680HSkXZ3G7NxzrQXTPfqP1R_DTS3RFPEywgHsb9ZbesIYZ-OfRs39A48v9p0 priority: 102 providerName: Scholars Portal |
| Title | The Prevalence and Genetic Diversity of PCV3 and PCV2 in Colombia and PCV4 Survey during 2015–2016 and 2018–2019 |
| URI | https://www.proquest.com/docview/2679808453/abstract/ https://search.proquest.com/docview/2681034703 https://pubmed.ncbi.nlm.nih.gov/PMC9228467 https://doaj.org/article/d84873d02b27428fbe43b903d4495b31 |
| Volume | 11 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9wwEB7yoNBL6St0m3RRIaeCs7ZGtrXHZpsQChuWvMjN6OVkS9cOm91Abv0P_Yf9JR3JdojprRdblmRbaCTNN5qHAPaNDas-j8L-m1Ayi7R1JhLEnWyMLk9L7yg8Pc1OLsX36_R6A9LOFyYY7Rs9P6h-Lg6q-W2wrbxbmFFnJzaaTSdjzj3bHG3CZo74TET_0UIgmeSNBhNJpPem1bc1keOeWB3hdfRn52CaCw_We-woRO3vQc2-oeQzznP8Gl61kJF9bZr2BjZc9RZeNIdIPr6DFVGa-UhMKvgPMVVZ5oNJU232rbO6YHXJZpMrDKWU4GxesQl9YaHnqssU7Hy9fHCPrPFdZNSx6Z9fv-mWhSqUkM3z-D1cHh9dTE6i9iyFyNAsXUUGpSLZxTlhCXHlWSZLJUoUymmTkdTk0Ca5KzkJp5mLjaO-kYhWJYnVSeoQd2Crqiv3AViO1iTcapFqLYj_jR2hPC-5ZaWJCX0N4EvXpcVdEzKjIFHDk6L4hxQDOPSd_lTRR7sOGfXypmhpXlhJlEIbc-0Vy7LUTqAex2gFiXcakwHsdSQr2il4X3CvX4qlSOkfn5-KafJ4jYiqXL32dWQSo6BVbwB5j9S9BvVLaFSGMNztKPz432_uwkvunSmCLcIebK2Wa_eJIM5KD2H78Oh0djYMWwR0nQo5DMP8LxnI_gU |
| link.rule.ids | 230,315,733,786,790,870,891,2115,2236,21416,24346,27957,27958,33779,33780,43840,53827,53829,74659 |
| linkProvider | National Library of Medicine |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwEB7BVgguFU81UMBInJAiEo-TeE-ILq0WaFcVtKi3yK_QPZCUfVTqjf_AP-SXMHaSbSMkTnFsK4lmYs_3ecZjgNfGhlmfx2H9TSiZx9o6EwuyTjZBV2SV3yh8NMunp-LTWXbWLbgtu7DKfk4ME7VtjF8jf8u9uyCRIsN3Fz9jf2qU9652R2jchi2BRFVGsLW3Pzv-slll8XhIpkXrzkTi9z7O-rwh3SzJ7hF4RxwYpJC3fwA2h6GSN2zPwX3Y7kAje99q-QHccvVDuNMeI3n1CFaka-ZzMamwg4ip2jKfTpp6sw993AVrKnY8-YahlQqczWs2oSf80HPVVwr2db24dFes3b3ISLTZn1-_6ZKHLlSQ7f34MZwe7J9MpnF3mkJsaJyuYoNSEXtxTljCXEWey0qJCoVy2uTEmxzatHAVJ3qau8Q4ojIS0ao0tTrNHOITGNVN7XaAFWhNyq0WmdaCLODYEc7z3C2vTEL4K4I3vUjLizZpRklkw8u__Ef-Eex5oW86-nzXoaJZfC-74VNaScQKbcK1dy3LSjuBepygFUTwNKYR7PYqK7tBuCyvf5kIXm2aafh4n4iqXbP2fWSaoKB5L4JioOrBBw1b6vl5SMQ95tzDt6f_f_lLuDs9OTosDz_OPj-De9zvnwjhB7swWi3W7jmhmpV-0f26fwG75_Xz |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELagFagXxFOkFDASJ6SoicdxvCfUbrsqr9UKKOot8it0D03afSD1xn_gH_aXMHachQiJU5zYSqIZ2_N9nvGYkNfGhlmfpWH9jSspUm2dSTlaJ5uBK4vabxT-NBUnp_z9WXEW45-WMayynxPDRG1b49fI95l3F2SSF7Bfx7CI2dHk7eVV6k-Q8p7WeJzGbbJdclFgD98-PJ7OPm9WXDw2knnZuTYBub6PuT5vUU9LtIEI5AEGxink8B8Az2HY5F92aHKf3IsAkh50Gn9AbrnmIbnTHSl5_YisUO_U52VSYTcRVY2lPrU0tqZHfQwGbWs6G3-DUIsFRucNHeMbLvRc9Q85_bJe_HDXtNvJSFHMxc3PX3gRoQkWZHc_ekxOJ8dfxydpPFkhNThmV6kBqZDJOMct4q9SCFkrXgNXThuBHMqBzUtXM6SqwmXGIa2RAFbludV54QCekK2mbdxTQkuwJmdW80JrjtZw5BDzeR4napMhFkvIm16k1WWXQKNC4uHlX_0j_4QceqFvGvrc1-FBu_hexaFUWYkkC2zGtHczy1o7DnqUgeVI9jTkCdnrVVbFAbms_nSfhLzaVONQ8v4R1bh27dvIPAOOc2BCyoGqBz80rGnm5yEp94gxD-V2___xl-Qu9trq47vph2dkh_mtFCESYY9srRZr9xwBzkq_iD33N1B0-jA |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+Prevalence+and+Genetic+Diversity+of+PCV3+and+PCV2+in+Colombia+and+PCV4+Survey+during+2015-2016+and+2018-2019&rft.jtitle=Pathogens+%28Basel%29&rft.au=Vargas-Bermudez%2C+Diana+S&rft.au=Mogoll%C3%B3n%2C+Jos%C3%A9+Dar%C3%ADo&rft.au=Jaime%2C+Jairo&rft.date=2022-05-31&rft.issn=2076-0817&rft.eissn=2076-0817&rft.volume=11&rft.issue=6&rft_id=info:doi/10.3390%2Fpathogens11060633&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2076-0817&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2076-0817&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2076-0817&client=summon |