Liquid-Liquid Phase Transition Drives Intra-chloroplast Cargo Sorting

• Published in: Cell Vol. 180; no. 6; pp. 1144 - 1159.e20
• Main Authors: Ouyang, Min, Li, Xiaoyi, Zhang, Jing, Feng, Peiqiang, Pu, Hua, Kong, Lingxi, Bai, Zechen, Rong, Liwei, Xu, Xiumei, Chi, Wei, Wang, Qiang, Chen, Fan, Lu, Congming, Shen, Jianren, Zhang, Lixin
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 19.03.2020
• Subjects: ankyrin-repeat proteins; cargo sorting; chloroplast; intrinsically disordered regions; liquid-liquid phase separation; nuclear-encoded chloroplast proteins; thylakoid membranes; twin arginine translocation pathway; twin arginine translocation pathway; ankyrin-repeat proteins; cargo sorting; chloroplast; liquid-liquid phase separation; thylakoid membranes; nuclear-encoded chloroplast proteins; intrinsically disordered regions

In eukaryotic cells, organelle biogenesis is pivotal for cellular function and cell survival. Chloroplasts are unique organelles with a complex internal membrane network. The mechanisms of the migration of imported nuclear-encoded chloroplast proteins across the crowded stroma to thylakoid membranes...