Intestinal Blastocystis is linked to healthier diets and more favorable cardiometabolic outcomes in 56,989 individuals from 32 countries
Diet impacts human health, influencing body adiposity and the risk of developing cardiometabolic diseases. The gut microbiome is a key player in the diet-health axis, but while its bacterial fraction is widely studied, the role of micro-eukaryotes, including Blastocystis, is underexplored. We perfor...
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| Published in | Cell Vol. 187; no. 17; pp. 4554 - 4570.e18 |
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| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
22.08.2024
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| Abstract | Diet impacts human health, influencing body adiposity and the risk of developing cardiometabolic diseases. The gut microbiome is a key player in the diet-health axis, but while its bacterial fraction is widely studied, the role of micro-eukaryotes, including Blastocystis, is underexplored. We performed a global-scale analysis on 56,989 metagenomes and showed that human Blastocystis exhibits distinct prevalence patterns linked to geography, lifestyle, and dietary habits. Blastocystis presence defined a specific bacterial signature and was positively associated with more favorable cardiometabolic profiles and negatively with obesity (p < 1e–16) and disorders linked to altered gut ecology (p < 1e–8). In a diet intervention study involving 1,124 individuals, improvements in dietary quality were linked to weight loss and increases in Blastocystis prevalence (p = 0.003) and abundance (p < 1e–7). Our findings suggest a potentially beneficial role for Blastocystis, which may help explain personalized host responses to diet and downstream disease etiopathogenesis.
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•Prevalence of Blastocystis in the gut microbiome varies across geography and lifestyle•Healthier plant-based diets are linked with higher gut Blastocystis carriage•Blastocystis-positive subjects tend to have healthier cardiometabolic profiles•Blastocystis presence increases after a diet-improving intervention program
A global-scale metagenomic exploration of Blastocystis was performed from 56,989 individuals across 32 countries. Blastocystis was seen to be widely present in healthy adults, with prevalence and abundance patterns linked to geography, dietary habits, and cardiometabolic profiles. |
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| AbstractList | Diet impacts human health, influencing body adiposity and the risk of developing cardiometabolic diseases. The gut microbiome is a key player in the diet-health axis, but while its bacterial fraction is widely studied, the role of micro-eukaryotes, including Blastocystis, is underexplored. We performed a global-scale analysis on 56,989 metagenomes and showed that human Blastocystis exhibits distinct prevalence patterns linked to geography, lifestyle, and dietary habits. Blastocystis presence defined a specific bacterial signature and was positively associated with more favorable cardiometabolic profiles and negatively with obesity (p < 1e–16) and disorders linked to altered gut ecology (p < 1e–8). In a diet intervention study involving 1,124 individuals, improvements in dietary quality were linked to weight loss and increases in Blastocystis prevalence (p = 0.003) and abundance (p < 1e–7). Our findings suggest a potentially beneficial role for Blastocystis, which may help explain personalized host responses to diet and downstream disease etiopathogenesis.
[Display omitted]
•Prevalence of Blastocystis in the gut microbiome varies across geography and lifestyle•Healthier plant-based diets are linked with higher gut Blastocystis carriage•Blastocystis-positive subjects tend to have healthier cardiometabolic profiles•Blastocystis presence increases after a diet-improving intervention program
A global-scale metagenomic exploration of Blastocystis was performed from 56,989 individuals across 32 countries. Blastocystis was seen to be widely present in healthy adults, with prevalence and abundance patterns linked to geography, dietary habits, and cardiometabolic profiles. Diet impacts human health, influencing body adiposity and the risk of developing cardiometabolic diseases. The gut microbiome is a key player in the diet-health axis, but while its bacterial fraction is widely studied, the role of micro-eukaryotes, including Blastocystis, is underexplored. We performed a global-scale analysis on 56,989 metagenomes and showed that human Blastocystis exhibits distinct prevalence patterns linked to geography, lifestyle, and dietary habits. Blastocystis presence defined a specific bacterial signature and was positively associated with more favorable cardiometabolic profiles and negatively with obesity (p < 1e-16) and disorders linked to altered gut ecology (p < 1e-8). In a diet intervention study involving 1,124 individuals, improvements in dietary quality were linked to weight loss and increases in Blastocystis prevalence (p = 0.003) and abundance (p < 1e-7). Our findings suggest a potentially beneficial role for Blastocystis, which may help explain personalized host responses to diet and downstream disease etiopathogenesis.Diet impacts human health, influencing body adiposity and the risk of developing cardiometabolic diseases. The gut microbiome is a key player in the diet-health axis, but while its bacterial fraction is widely studied, the role of micro-eukaryotes, including Blastocystis, is underexplored. We performed a global-scale analysis on 56,989 metagenomes and showed that human Blastocystis exhibits distinct prevalence patterns linked to geography, lifestyle, and dietary habits. Blastocystis presence defined a specific bacterial signature and was positively associated with more favorable cardiometabolic profiles and negatively with obesity (p < 1e-16) and disorders linked to altered gut ecology (p < 1e-8). In a diet intervention study involving 1,124 individuals, improvements in dietary quality were linked to weight loss and increases in Blastocystis prevalence (p = 0.003) and abundance (p < 1e-7). Our findings suggest a potentially beneficial role for Blastocystis, which may help explain personalized host responses to diet and downstream disease etiopathogenesis. Diet impacts human health, influencing body adiposity and the risk of developing cardiometabolic diseases. The gut microbiome is a key player in the diet-health axis, but while its bacterial fraction is widely studied, the role of micro-eukaryotes, including Blastocystis, is underexplored. We performed a global-scale analysis on 56,989 metagenomes and showed that human Blastocystis exhibits distinct prevalence patterns linked to geography, lifestyle, and dietary habits. Blastocystis presence defined a specific bacterial signature and was positively associated with more favorable cardiometabolic profiles and negatively with obesity (p < 1e-16) and disorders linked to altered gut ecology (p < 1e-8). In a diet intervention study involving 1,124 individuals, improvements in dietary quality were linked to weight loss and increases in Blastocystis prevalence (p = 0.003) and abundance (p < 1e-7). Our findings suggest a potentially beneficial role for Blastocystis, which may help explain personalized host responses to diet and downstream disease etiopathogenesis. |
| Author | Arrè, Alberto Cucca, Francesco Bakker, Elco Pitzalis, Maristella Wolf, Jonathan Ercolini, Danilo Kim, Hanseul Valles-Colomer, Mireia Masala, Marco Leeming, Emily R. Pala, Mauro Berry, Sarah E. Asnicar, Francesco Blanco-Míguez, Aitor Segata, Nicola Andreu-Sánchez, Sergio Busonero, Fabio McIver, Lauren J. Huttenhower, Curtis Maschio, Andrea Bermingham, Kate M. Fu, Jingyuan Davies, Richard Lobina, Monia Pasolli, Edoardo Manghi, Paolo Cacciò, Simone M. Spector, Tim D. Giordano, Francesca Hadjigeorgiou, George Nguyen, Long H. Fiorillo, Edoardo Chan, Andrew T. Zhernakova, Alexandra Piperni, Elisa Manara, Serena |
| Author_xml | – sequence: 1 givenname: Elisa surname: Piperni fullname: Piperni, Elisa organization: Department CIBIO, University of Trento, Trento, Italy – sequence: 2 givenname: Long H. surname: Nguyen fullname: Nguyen, Long H. organization: Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA – sequence: 3 givenname: Paolo surname: Manghi fullname: Manghi, Paolo organization: Department CIBIO, University of Trento, Trento, Italy – sequence: 4 givenname: Hanseul surname: Kim fullname: Kim, Hanseul organization: Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA – sequence: 5 givenname: Edoardo surname: Pasolli fullname: Pasolli, Edoardo organization: Department of Agricultural Sciences, University of Naples Federico II, Portici, Italy – sequence: 6 givenname: Sergio surname: Andreu-Sánchez fullname: Andreu-Sánchez, Sergio organization: Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands – sequence: 7 givenname: Alberto surname: Arrè fullname: Arrè, Alberto organization: Department CIBIO, University of Trento, Trento, Italy – sequence: 8 givenname: Kate M. surname: Bermingham fullname: Bermingham, Kate M. organization: Zoe Ltd, London, UK – sequence: 9 givenname: Aitor surname: Blanco-Míguez fullname: Blanco-Míguez, Aitor organization: Department CIBIO, University of Trento, Trento, Italy – sequence: 10 givenname: Serena surname: Manara fullname: Manara, Serena organization: Department CIBIO, University of Trento, Trento, Italy – sequence: 11 givenname: Mireia surname: Valles-Colomer fullname: Valles-Colomer, Mireia organization: Department CIBIO, University of Trento, Trento, Italy – sequence: 12 givenname: Elco surname: Bakker fullname: Bakker, Elco organization: Zoe Ltd, London, UK – sequence: 13 givenname: Fabio surname: Busonero fullname: Busonero, Fabio organization: Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy – sequence: 14 givenname: Richard surname: Davies fullname: Davies, Richard organization: Zoe Ltd, London, UK – sequence: 15 givenname: Edoardo surname: Fiorillo fullname: Fiorillo, Edoardo organization: Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy – sequence: 16 givenname: Francesca surname: Giordano fullname: Giordano, Francesca organization: Zoe Ltd, London, UK – sequence: 17 givenname: George surname: Hadjigeorgiou fullname: Hadjigeorgiou, George organization: Zoe Ltd, London, UK – sequence: 18 givenname: Emily R. surname: Leeming fullname: Leeming, Emily R. organization: Department of Twins Research and Genetic Epidemiology, King’s College London, London, UK – sequence: 19 givenname: Monia surname: Lobina fullname: Lobina, Monia organization: Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy – sequence: 20 givenname: Marco surname: Masala fullname: Masala, Marco organization: Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy – sequence: 21 givenname: Andrea surname: Maschio fullname: Maschio, Andrea organization: Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy – sequence: 22 givenname: Lauren J. surname: McIver fullname: McIver, Lauren J. organization: Harvard T.H. Chan School of Public Health, Boston, MA, USA – sequence: 23 givenname: Mauro surname: Pala fullname: Pala, Mauro organization: Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy – sequence: 24 givenname: Maristella surname: Pitzalis fullname: Pitzalis, Maristella organization: Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy – sequence: 25 givenname: Jonathan surname: Wolf fullname: Wolf, Jonathan organization: Zoe Ltd, London, UK – sequence: 26 givenname: Jingyuan surname: Fu fullname: Fu, Jingyuan organization: Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands – sequence: 27 givenname: Alexandra surname: Zhernakova fullname: Zhernakova, Alexandra organization: Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands – sequence: 28 givenname: Simone M. surname: Cacciò fullname: Cacciò, Simone M. organization: Department of Infectious Diseases, Istituto Superiore Di Sanità, Rome, Italy – sequence: 29 givenname: Francesco surname: Cucca fullname: Cucca, Francesco organization: Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy – sequence: 30 givenname: Sarah E. surname: Berry fullname: Berry, Sarah E. organization: Department of Nutritional Sciences, King’s College London, London, UK – sequence: 31 givenname: Danilo surname: Ercolini fullname: Ercolini, Danilo organization: Department of Agricultural Sciences, University of Naples Federico II, Portici, Italy – sequence: 32 givenname: Andrew T. surname: Chan fullname: Chan, Andrew T. organization: Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA – sequence: 33 givenname: Curtis surname: Huttenhower fullname: Huttenhower, Curtis organization: Harvard T.H. Chan School of Public Health, Boston, MA, USA – sequence: 34 givenname: Tim D. surname: Spector fullname: Spector, Tim D. organization: Department of Twins Research and Genetic Epidemiology, King’s College London, London, UK – sequence: 35 givenname: Nicola orcidid: 0000-0002-1583-5794 surname: Segata fullname: Segata, Nicola email: nicola.segata@unitn.it organization: Department CIBIO, University of Trento, Trento, Italy – sequence: 36 givenname: Francesco surname: Asnicar fullname: Asnicar, Francesco email: f.asnicar@unitn.it organization: Department CIBIO, University of Trento, Trento, Italy |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/38981480$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/j.heliyon.2022.e12592 10.1038/s41591-022-01964-3 10.1016/j.meegid.2015.02.012 10.1093/ajcn/80.2.271 10.1016/j.cub.2023.04.011 10.1038/s41587-023-01688-w 10.1016/j.actatropica.2012.12.011 10.1038/ismej.2017.139 10.1373/clinchem.2014.232918 10.1128/mSystems.00201-17 10.1038/s41592-019-0686-2 10.1016/j.cell.2018.10.029 10.1161/01.ATV.10.4.497 10.1038/nature18927 10.1053/j.gastro.2014.01.058 10.1038/s41579-023-00984-1 10.1002/0471250953.bi1112s47 10.1073/pnas.1319284111 10.1038/s42255-021-00383-x 10.7554/eLife.65088 10.1038/s41591-020-01183-8 10.1016/j.cub.2021.09.031 10.1016/j.cmi.2017.05.015 10.7717/peerj.9001 10.1007/s00436-007-0712-7 10.1038/s41591-019-0663-4 10.1016/j.cub.2015.04.055 10.1007/s10552-019-01176-0 10.1126/science.aaz3834 10.1038/nature12820 10.1073/pnas.1005963107 10.1161/01.cir.0000437741.48606.98 10.1017/S1368980017000234 10.1177/17562848221091524 10.3390/microorganisms10020326 10.1038/s41591-020-01223-3 10.1161/CIR.0000000000001031 10.1128/JCM.02520-15 10.1038/s41467-019-12476-z 10.1016/j.pt.2019.12.009 10.1371/journal.pcbi.1004977 10.1126/sciadv.1500183 10.1038/s41586-022-05620-1 10.1136/gutjnl-2019-320438 10.1053/j.gastro.2019.12.029 10.1016/j.chom.2019.01.004 10.1016/j.cels.2016.10.004 10.1002/ajpa.23978 10.1016/j.chom.2018.06.005 10.1016/j.meegid.2016.08.018 10.1038/nmeth.4468 10.1136/gutjnl-2021-325168 10.25080/Majora-92bf1922-011 10.1038/nature11450 10.1128/JCM.43.1.348-355.2005 10.1371/journal.pone.0264649 10.1016/j.pt.2018.02.004 10.1038/s41586-022-04567-7 10.1016/B978-0-12-407706-5.00001-0 10.1007/s00436-003-0995-2 10.1079/PHN2000102 10.1016/j.jacc.2017.05.047 10.1136/gutjnl-2018-316106 10.1186/s40168-020-00832-x 10.1371/journal.ppat.1005039 10.1016/j.cell.2023.05.046 10.1002/cpmc.18 10.1093/ije/dyab257 10.3390/ani12212992 10.1093/schbul/18.2.171 10.1016/j.protis.2013.05.003 10.3389/fmicb.2021.641483 10.1093/bioinformatics/btp352 10.1186/s13071-022-05194-x 10.1503/cmaj.121950 10.1016/j.pt.2017.08.005 10.1016/j.celrep.2015.03.049 10.1186/s13059-015-0639-8 10.1161/CIRCULATIONAHA.107.699579 10.1001/jama.2009.1619 10.1111/nbu.12124 10.1146/annurev-publhealth-031811-124646 10.1016/j.cell.2019.01.001 10.1016/j.chom.2019.08.018 10.3390/nu7010017 10.1038/s41579-019-0191-8 10.1016/S0140-6736(19)30041-8 10.21105/joss.01026 10.1016/j.rvsc.2020.09.031 10.1038/s41586-021-03532-0 10.1161/CIRCULATIONAHA.111.067264 10.1038/nmeth.1923 10.1073/pnas.0706625104 10.1017/S0031182018000033 10.1186/s13071-022-05435-z 10.1016/j.parint.2016.05.015 10.1038/nature11053 10.1093/cid/ciz1122 10.1016/j.cca.2015.11.001 10.1016/j.jacc.2017.12.006 10.1371/journal.pgen.0020132 10.1038/ncomms7505 10.1093/aje/154.12.1089 10.1016/S0140-6736(10)60545-4 10.1093/aje/kwaa280 10.1017/S000711452200160X 10.1016/j.jand.2012.12.016 10.1126/science.abb5352 10.1038/s41467-019-13721-1 10.1001/jama.2017.3303 10.1111/j.2517-6161.1995.tb02031.x 10.3945/an.115.008623 10.1038/s41576-022-00529-x 10.1136/gutjnl-2019-319548 10.1038/ncomms4654 10.1111/1574-6941.12396 10.1038/s41591-020-0934-0 10.1186/1471-2334-14-164 |
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| Keywords | diet and microbiome integrative metagenomics metagenomics microbiome meta-analysis transkingdom microbiome analysis micro-eukaryote cardiometabolic health human gut microbiome Blastocystis hominis |
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| References | Rampelli, Schnorr, Consolandi, Turroni, Severgnini, Peano, Brigidi, Crittenden, Henry, Candela (bib117) 2015; 25 Berry, Valdes, Drew, Asnicar, Mazidi, Wolf, Capdevila, Hadjigeorgiou, Davies, Al Khatib (bib18) 2020; 26 (bib2) 2019; 393 Albenberg, Wu (bib49) 2014; 146 (bib131) 2022 Qin, Li, Cai, Li, Zhu, Zhang, Liang, Zhang, Guan, Shen (bib17) 2012; 490 (bib121) 2024 Asnicar, Berry, Valdes, Nguyen, Piccinno, Drew, Leeming, Gibson, Le Roy, Khatib (bib7) 2021; 27 Carter, Olm, Merrill, Dahan, Tripathi, Spencer, Yu, Jain, Neff, Jha (bib46) 2023; 186 Després (bib70) 2012; 126 Tett, Huang, Asnicar, Fehlner-Peach, Pasolli, Karcher, Armanini, Manghi, Bonham, Zolfo (bib27) 2019; 26 Chabé, Lokmer, Ségurel (bib89) 2017; 33 Wang, Nguyen, Li, Yan, Ma, Rinott, Ivey, Shai, Willett, Hu (bib103) 2021; 27 Beghini, McIver, Blanco-Míguez, Dubois, Asnicar, Maharjan, Mailyan, Manghi, Scholz, Thomas (bib99) 2021; 10 Weir, Jan (bib73) 2022 Stensvold, Clark (bib13) 2016; 65 Després, Moorjani, Lupien, Tremblay, Nadeau, Bouchard (bib71) 1990; 10 (bib4) 2022 Pandey, Verma, Marathe, Shetty, Bavdekar, Patole, Stensvold, Shouche (bib39) 2015; 31 Laforest-Lapointe, Arrieta (bib94) 2018; 3 Min, Min (bib59) 2013; 185 Li, Handsaker, Wysoker, Fennell, Ruan, Homer, Marth, Abecasis, Durbin (bib97) 2009; 25 Wyatt, Berry, Finlayson, O’Driscoll, Hadjigeorgiou, Drew, Khatib, Nguyen, Linenberg, Chan (bib19) 2021; 3 Valles-Colomer, Blanco-Míguez, Manghi, Asnicar, Dubois, Golzato, Armanini, Cumbo, Huang, Manara (bib40) 2023; 614 Mehta, Lochhead, Wang, Ma, Nguyen, Kochar, Huttenhower, Grodstein, Chan (bib104) 2022; 17 Frank, St Amand, Feldman, Boedeker, Harpaz, Pace (bib15) 2007; 104 Hagan, Hofman, Hübner, Reinhard, Schnorr, Lewis, Sankaranarayanan, Warinner (bib31) 2020; 171 Terveer, van Beurden, Goorhuis, Seegers, Bauer, van Nood, Dijkgraaf, Mulder, Vandenbroucke-Grauls, Verspaget (bib90) 2017; 23 Voigt, Costea, Kultima, Li, Zeller, Sunagawa, Bork (bib106) 2015; 16 Subar, Thompson, Kipnis, Midthune, Hurwitz, McNutt, McIntosh, Rosenfeld (bib119) 2001; 154 Hirata, Nakamura, Kinjo, Hokama, Kinjo, Yamane, Fujita (bib35) 2007; 101 Lyubchich, Gel, Vishwakarma (bib128) 2023 Seabold, Perktold (bib127) 2010 Vangay, Johnson, Ward, Al-Ghalith, Shields-Cutler, Hillmann, Lucas, Beura, Thompson, Till (bib52) 2018; 175 Ianiro, Punčochář, Karcher, Porcari, Armanini, Asnicar, Beghini, Blanco-Míguez, Cumbo, Manghi (bib87) 2022; 28 Pasolli, Schiffer, Manghi, Renson, Obenchain, Truong, Beghini, Malik, Ramos, Dowd (bib25) 2017; 14 Satija, Bhupathiraju, Spiegelman, Chiuve, Manson, Willett, Rexrode, Rimm, Hu (bib54) 2017; 70 Clemente, Pehrsson, Blaser, Sandhu, Gao, Wang, Magris, Hidalgo, Contreras, Noya-Alarcón (bib114) 2015; 1 Holmes, Millwood, Kartsonaki, Hill, Bennett, Boxall, Guo, Xu, Bian, Hu (bib66) 2018; 71 Quinlan (bib98) 2014; 47 McGue (bib111) 1992; 18 Monteiro, Cannon, Lawrence, da Costa Louzada, Pereira Machado (bib123) 2019; 49 Meslier, Laiola, Roager, De Filippis, Roume, Quinquis, Giacco, Mennella, Ferracane, Pons (bib21) 2020; 69 Bermingham, Linenberg, Polidori, Wolf, Bulsiewicz, Spector, Berry (bib101) 2023; 91 Vallat (bib129) 2018; 3 Vojinovic, Radjabzadeh, Kurilshikov, Amin, Wijmenga, Franke, Ikram, Uitterlinden, Zhernakova, Fu (bib63) 2019; 10 Ianiro, Iorio, Porcari, Masucci, Sanguinetti, Perno, Gasbarrini, Putignani, Cammarota (bib83) 2022; 15 Tito, Chaffron, Caenepeel, Lima-Mendez, Wang, Vieira-Silva, Falony, Hildebrand, Darzi, Rymenans (bib91) 2019; 68 Sijtsma, Rienks, van der Harst, Navis, Rosmalen, Dotinga (bib109) 2022; 51 Benjamini, Hochberg (bib126) 1995; 57 Otvos, Shalaurova, Wolak-Dinsmore, Connelly, Mackey, Stein, Tracy (bib64) 2015; 61 Guenther, Casavale, Reedy, Kirkpatrick, Hiza, Kuczynski, Kahle, Krebs-Smith (bib122) 2013; 113 Borry, Cordova, Perri, Wibowo, Prasad Honap, Ko, Yu, Britton, Girdland-Flink, Power (bib30) 2020; 8 Arnett, Blumenthal, Albert, Buroker, Goldberger, Hahn, Himmelfarb, Khera, Lloyd-Jones, McEvoy (bib56) 2019; 140 Pasolli, Truong, Malik, Waldron, Segata (bib78) 2016; 12 Goff, Lloyd-Jones, Bennett, Coady, D’Agostino, Gibbons, Greenland, Lackland, Levy, O’Donnell (bib124) 2014; 129 Sonnenburg, Sonnenburg (bib45) 2019; 17 Stensvold, Clark (bib10) 2020; 36 Berry, Drew, Linenberg, Wolf, Hadjigeorgiou, Davies, Khatib, Hart, Surdulescu, Yarand (bib100) 2020 Scanlan, Knight, Song, Ackermann, Cotter (bib36) 2016; 45 Wibowo, Yang, Borry, Hübner, Huang, Tierney, Zimmerman, Barajas-Olmos, Contreras-Cubas, García-Ortiz (bib28) 2021; 594 Yoshikawa, Wu, Kimata, Iseki, Ali, Hossain, Zaman, Haque, Takahashi (bib34) 2004; 92 Cammarota, Ianiro, Kelly, Mullish, Allegretti, Kassam, Putignani, Fischer, Keller, Costello (bib86) 2019; 68 Langmead, Salzberg (bib96) 2012; 9 Alfellani, Taner-Mulla, Jacob, Imeede, Yoshikawa, Stensvold, Clark (bib32) 2013; 164 Yatsunenko, Rey, Manary, Trehan, Dominguez-Bello, Contreras, Magris, Hidalgo, Baldassano, Anokhin (bib53) 2012; 486 Akinkuolie, Buring, Ridker, Mora (bib65) 2014; 3 Clark, van der Giezen, Alfellani, Stensvold (bib79) 2013 Scanlan, Hill, Ross, Ryan, Stanton, Cotter (bib38) 2018; 145 Lukeš, Stensvold, Jirků-Pomajbíková, Wegener Parfrey (bib82) 2015; 11 D’Agostino, Vasan, Pencina, Wolf, Cobain, Massaro, Kannel (bib57) 2008; 117 Billy, Lhotská, Jirků, Kadlecová, Frgelecová, Parfrey, Pomajbíková (bib67) 2021; 12 Deng, Tan (bib68) 2022; 15 Jiménez, Muñoz, Ramírez (bib11) 2022; 8 Tarallo, Ferrero, De Filippis, Francavilla, Pasolli, Panero, Cordero, Segata, Grioni, Pensa (bib22) 2022; 71 Stensvold, Sørland, Berg, Andersen, van der Giezen, Bowtell, El-Badry, Belkessa, Kurt, Nielsen (bib14) 2022; 10 (bib130) 2010 Clark, Stensvold (bib93) 2016; 43 Hublin, Maloney, Santin (bib44) 2021; 135 Conlon, Bird (bib51) 2014; 7 Levin, Raab, Pinto, Rothschild, Zanir, Godneva, Mellul, Futorian, Gal, Leviatan (bib110) 2021; 372 Al-Shaar, Yuan, Rosner, Dean, Ivey, Clowry, Sampson, Barnett, Rood, Harnack (bib23) 2021; 190 Huang, Trudel-Fitzgerald, Poole, Sawyer, Kubzansky, Hankinson, Okereke, Tworoger (bib24) 2019; 30 Monteiro, Cannon, Moubarac, Levy, Louzada, Jaime (bib55) 2018; 21 VanEvery, Franzosa, Nguyen, Huttenhower (bib76) 2023; 24 (bib3) 2020 Rifkin, Vikram, Ramond, Rey-Iglesia, Brand, Porraz, Val, Hall, Woodborne, Le Bailly (bib29) 2020; 8 Visconti, Le Roy, Rosa, Rossi, Martin, Mohney, Li, de Rinaldis, Bell, Venter (bib47) 2019; 10 Sarwar, Sandhu, Ricketts, Butterworth, Di Angelantonio, Boekholdt, Ouwehand, Watkins, Samani (bib61) 2010; 375 De Filippis, Pasolli, Tett, Tarallo, Naccarati, De Angelis, Neviani, Cocolin, Gobbetti, Segata (bib20) 2019; 25 Finlay (bib95) 2020; 367 Willett, Stampfer (bib1) 2013; 34 Ferretti, Pasolli, Tett, Asnicar, Gorfer, Fedi, Armanini, Truong, Manara, Zolfo (bib41) 2018; 24 Manara, Selma-Royo, Huang, Asnicar, Armanini, Blanco-Miguez, Cumbo, Golzato, Manghi, Pinto (bib42) 2023; 33 Scanlan, Stensvold, Rajilić-Stojanović, Heilig, De Vos, O’Toole, Cotter (bib88) 2014; 90 Shen, Punyanitya, Wang, Gallagher, St-Onge, Albu, Heymsfield, Heshka (bib72) 2004; 80 Stensvold, van der Giezen (bib81) 2018; 34 Patel, Taveira, Choudhary, Whitlatch, Wu (bib58) 2012; 1 Blanco-Míguez, Beghini, Cumbo, McIver, Thompson, Zolfo, Manghi, Dubois, Huang, Thomas (bib84) 2023; 41 Noël, Dufernez, Gerbod, Edgcomb, Delgado-Viscogliosi, Ho, Singh, Wintjens, Sogin, Capron (bib80) 2005; 43 Deng, Lee, Tan (bib69) 2022; 15 De Filippo, Cavalieri, Di Paola, Ramazzotti, Poullet, Massart, Collini, Pieraccini, Lionetti (bib112) 2010; 107 Maixner, Sarhan, Huang, Tett, Schoenafinger, Zingale, Blanco-Míguez, Manghi, Cemper-Kiesslich, Rosendahl (bib26) 2021; 31 Dashti, Scheer, Jacques, Lamon-Fava, Ordovás (bib74) 2015; 6 Obregon-Tito, Tito, Metcalf, Sankaranarayanan, Clemente, Ursell, Zech Xu, Van Treuren, Knight, Gaffney (bib116) 2015; 6 El Safadi, Gaayeb, Meloni, Cian, Poirier, Wawrzyniak, Delbac, Dabboussi, Delhaes, Seck (bib37) 2014; 14 Ni, Dong, Fan, Wan, Teng, Zhu, Liang, Xu, Yao, Zhang (bib43) 2022; 12 Xie, Guo, Zhong, Feng, Lan, Qin, Ward, Jackson, Xia, Chen (bib48) 2016; 3 Roe, Pinchen, Church, Finglas (bib120) 2015; 40 Patnode, Evans, Senger, Redmond, Lin (bib6) 2017; 318 Alfellani, Stensvold, Vidal-Lapiedra, Onuoha, Fagbenro-Beyioku, Clark (bib12) 2013; 126 Thomas, Manghi, Asnicar, Pasolli, Armanini, Zolfo, Beghini, Manara, Karcher, Pozzi (bib16) 2019; 25 Brito, Yilmaz, Huang, Xu, Jupiter, Jenkins, Naisilisili, Tamminen, Smillie, Wortman (bib33) 2016; 535 Nguyen, Ma, Wang, Cao, Mallick, Gerbaba, Lloyd-Price, Abu-Ali, Hall, Sikavi (bib102) 2020; 158 Beghini, Pasolli, Truong, Putignani, Cacciò, Segata (bib9) 2017; 11 Gacesa, Kurilshikov, Vich Vila, Sinha, Klaassen, Bolte, Andreu-Sánchez, Chen, Collij, Hu (bib108) 2022; 604 Hall (bib75) 2022; 128 Lichtenstein, Appel, Vadiveloo, Hu, Kris-Etherton, Rebholz, Sacks, Thorndike, Van Horn, Wylie-Rosett (bib5) 2021; 144 Schnorr, Candela, Rampelli, Centanni, Consolandi, Basaglia, Turroni, Biagi, Peano, Severgnini (bib113) 2014; 5 Connelly, Gruppen, Wolak-Dinsmore, Matyus, Riphagen, Shalaurova, Bakker, Otvos, Dullaart (bib62) 2016; 452 Asnicar, Thomas, Passerini, Waldron, Segata (bib77) 2024; 22 Martínez, Stegen, Maldonado-Gómez, Eren, Siba, Greenhill, Walter (bib115) 2015; 11 Virtanen, Gommers, Oliphant, Haberland, Reddy, Cournapeau, Burovski, Peterson, Weckesser, Bright (bib125) 2020; 17 Di Angelantonio, Sarwar, Perry, Kaptoge, Ray, Thompson, Wood, Lewington, Sattar (bib60) 2009; 302 Andersen, Stensvold (bib8) 2016; 54 Terveer, van Gool, Ooijevaar, Sanders, Boeije-Koppenol, Keller, Bart, Kuijper (bib92) 2020; 71 Franzosa, Morgan, Segata, Waldron, Reyes, Earl, Giannoukos, Boylan, Ciulla, Gevers (bib105) 2014; 111 Pilia, Chen, Scuteri, Orrú, Albai, Dei, Lai, Usala, Lai, Loi (bib107) 2006; 2 Pasolli, Asnicar, Manara, Zolfo, Karcher, Armanini, Beghini, Manghi, Tett, Ghensi (bib85) 2019; 176 David, Maurice, Carmody, Gootenberg, Button, Wolfe, Ling, Devlin, Varma, Fischbach (bib50) 2014; 505 Bingham, Welch, McTaggart, Mulligan, Runswick, Luben, Oakes, Khaw, Wareham, Day (bib118) 2001; 4 (10.1016/j.cell.2024.06.018_bib3) 2020 Frank (10.1016/j.cell.2024.06.018_bib15) 2007; 104 Xie (10.1016/j.cell.2024.06.018_bib48) 2016; 3 Sijtsma (10.1016/j.cell.2024.06.018_bib109) 2022; 51 Monteiro (10.1016/j.cell.2024.06.018_bib123) 2019; 49 David (10.1016/j.cell.2024.06.018_bib50) 2014; 505 Holmes (10.1016/j.cell.2024.06.018_bib66) 2018; 71 Wibowo (10.1016/j.cell.2024.06.018_bib28) 2021; 594 Cammarota (10.1016/j.cell.2024.06.018_bib86) 2019; 68 Patel (10.1016/j.cell.2024.06.018_bib58) 2012; 1 Lyubchich (10.1016/j.cell.2024.06.018_bib128) VanEvery (10.1016/j.cell.2024.06.018_bib76) 2023; 24 Deng (10.1016/j.cell.2024.06.018_bib68) 2022; 15 Stensvold (10.1016/j.cell.2024.06.018_bib14) 2022; 10 Sarwar (10.1016/j.cell.2024.06.018_bib61) 2010; 375 Clark (10.1016/j.cell.2024.06.018_bib79) 2013 Yoshikawa (10.1016/j.cell.2024.06.018_bib34) 2004; 92 Weir (10.1016/j.cell.2024.06.018_bib73) 2022 Roe (10.1016/j.cell.2024.06.018_bib120) 2015; 40 Monteiro (10.1016/j.cell.2024.06.018_bib55) 2018; 21 Tito (10.1016/j.cell.2024.06.018_bib91) 2019; 68 Stensvold (10.1016/j.cell.2024.06.018_bib10) 2020; 36 Borry (10.1016/j.cell.2024.06.018_bib30) 2020; 8 Scanlan (10.1016/j.cell.2024.06.018_bib38) 2018; 145 Terveer (10.1016/j.cell.2024.06.018_bib92) 2020; 71 Lichtenstein (10.1016/j.cell.2024.06.018_bib5) 2021; 144 Al-Shaar (10.1016/j.cell.2024.06.018_bib23) 2021; 190 Pasolli (10.1016/j.cell.2024.06.018_bib25) 2017; 14 Goff (10.1016/j.cell.2024.06.018_bib124) 2014; 129 Yatsunenko (10.1016/j.cell.2024.06.018_bib53) 2012; 486 Otvos (10.1016/j.cell.2024.06.018_bib64) 2015; 61 Obregon-Tito (10.1016/j.cell.2024.06.018_bib116) 2015; 6 Levin (10.1016/j.cell.2024.06.018_bib110) 2021; 372 Clemente (10.1016/j.cell.2024.06.018_bib114) 2015; 1 (10.1016/j.cell.2024.06.018_bib131) 2022 Valles-Colomer (10.1016/j.cell.2024.06.018_bib40) 2023; 614 Hirata (10.1016/j.cell.2024.06.018_bib35) 2007; 101 (10.1016/j.cell.2024.06.018_bib130) 2010 Vangay (10.1016/j.cell.2024.06.018_bib52) 2018; 175 Ni (10.1016/j.cell.2024.06.018_bib43) 2022; 12 Billy (10.1016/j.cell.2024.06.018_bib67) 2021; 12 Scanlan (10.1016/j.cell.2024.06.018_bib88) 2014; 90 Ferretti (10.1016/j.cell.2024.06.018_bib41) 2018; 24 Martínez (10.1016/j.cell.2024.06.018_bib115) 2015; 11 Laforest-Lapointe (10.1016/j.cell.2024.06.018_bib94) 2018; 3 McGue (10.1016/j.cell.2024.06.018_bib111) 1992; 18 Andersen (10.1016/j.cell.2024.06.018_bib8) 2016; 54 Manara (10.1016/j.cell.2024.06.018_bib42) 2023; 33 Berry (10.1016/j.cell.2024.06.018_bib100) 2020 Pasolli (10.1016/j.cell.2024.06.018_bib85) 2019; 176 Visconti (10.1016/j.cell.2024.06.018_bib47) 2019; 10 Rampelli (10.1016/j.cell.2024.06.018_bib117) 2015; 25 Terveer (10.1016/j.cell.2024.06.018_bib90) 2017; 23 Scanlan (10.1016/j.cell.2024.06.018_bib36) 2016; 45 Subar (10.1016/j.cell.2024.06.018_bib119) 2001; 154 Li (10.1016/j.cell.2024.06.018_bib97) 2009; 25 Langmead (10.1016/j.cell.2024.06.018_bib96) 2012; 9 Voigt (10.1016/j.cell.2024.06.018_bib106) 2015; 16 De Filippo (10.1016/j.cell.2024.06.018_bib112) 2010; 107 Finlay (10.1016/j.cell.2024.06.018_bib95) 2020; 367 Seabold (10.1016/j.cell.2024.06.018_bib127) 2010 Stensvold (10.1016/j.cell.2024.06.018_bib81) 2018; 34 Virtanen (10.1016/j.cell.2024.06.018_bib125) 2020; 17 Benjamini (10.1016/j.cell.2024.06.018_bib126) 1995; 57 Mehta (10.1016/j.cell.2024.06.018_bib104) 2022; 17 De Filippis (10.1016/j.cell.2024.06.018_bib20) 2019; 25 D’Agostino (10.1016/j.cell.2024.06.018_bib57) 2008; 117 Després (10.1016/j.cell.2024.06.018_bib70) 2012; 126 Qin (10.1016/j.cell.2024.06.018_bib17) 2012; 490 Tarallo (10.1016/j.cell.2024.06.018_bib22) 2022; 71 Stensvold (10.1016/j.cell.2024.06.018_bib13) 2016; 65 Wyatt (10.1016/j.cell.2024.06.018_bib19) 2021; 3 Brito (10.1016/j.cell.2024.06.018_bib33) 2016; 535 Wang (10.1016/j.cell.2024.06.018_bib103) 2021; 27 Alfellani (10.1016/j.cell.2024.06.018_bib32) 2013; 164 Schnorr (10.1016/j.cell.2024.06.018_bib113) 2014; 5 El Safadi (10.1016/j.cell.2024.06.018_bib37) 2014; 14 Dashti (10.1016/j.cell.2024.06.018_bib74) 2015; 6 Akinkuolie (10.1016/j.cell.2024.06.018_bib65) 2014; 3 Noël (10.1016/j.cell.2024.06.018_bib80) 2005; 43 Jiménez (10.1016/j.cell.2024.06.018_bib11) 2022; 8 Meslier (10.1016/j.cell.2024.06.018_bib21) 2020; 69 Berry (10.1016/j.cell.2024.06.018_bib18) 2020; 26 (10.1016/j.cell.2024.06.018_bib4) 2022 Di Angelantonio (10.1016/j.cell.2024.06.018_bib60) 2009; 302 Beghini (10.1016/j.cell.2024.06.018_bib9) 2017; 11 Huang (10.1016/j.cell.2024.06.018_bib24) 2019; 30 Hublin (10.1016/j.cell.2024.06.018_bib44) 2021; 135 Gacesa (10.1016/j.cell.2024.06.018_bib108) 2022; 604 Bermingham (10.1016/j.cell.2024.06.018_bib101) 2023; 91 Thomas (10.1016/j.cell.2024.06.018_bib16) 2019; 25 Després (10.1016/j.cell.2024.06.018_bib71) 1990; 10 Ianiro (10.1016/j.cell.2024.06.018_bib87) 2022; 28 Asnicar (10.1016/j.cell.2024.06.018_bib77) 2024; 22 Sonnenburg (10.1016/j.cell.2024.06.018_bib45) 2019; 17 Carter (10.1016/j.cell.2024.06.018_bib46) 2023; 186 Vallat (10.1016/j.cell.2024.06.018_bib129) 2018; 3 Beghini (10.1016/j.cell.2024.06.018_bib99) 2021; 10 Blanco-Míguez (10.1016/j.cell.2024.06.018_bib84) 2023; 41 Pandey (10.1016/j.cell.2024.06.018_bib39) 2015; 31 Albenberg (10.1016/j.cell.2024.06.018_bib49) 2014; 146 Willett (10.1016/j.cell.2024.06.018_bib1) 2013; 34 (10.1016/j.cell.2024.06.018_bib2) 2019; 393 Hagan (10.1016/j.cell.2024.06.018_bib31) 2020; 171 Conlon (10.1016/j.cell.2024.06.018_bib51) 2014; 7 Maixner (10.1016/j.cell.2024.06.018_bib26) 2021; 31 Clark (10.1016/j.cell.2024.06.018_bib93) 2016; 43 Patnode (10.1016/j.cell.2024.06.018_bib6) 2017; 318 Franzosa (10.1016/j.cell.2024.06.018_bib105) 2014; 111 (10.1016/j.cell.2024.06.018_bib121) 2024 Rifkin (10.1016/j.cell.2024.06.018_bib29) 2020; 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33 |
| References_xml | – volume: 25 start-page: 1948 year: 2019 ident: bib16 article-title: Author Correction: Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation publication-title: Nat. Med. – volume: 15 start-page: 312 year: 2022 ident: bib69 article-title: Infection with pathogenic Blastocystis ST7 is associated with decreased bacterial diversity and altered gut microbiome profiles in diarrheal patients publication-title: Parasit. Vectors – volume: 49 year: 2019 ident: bib123 article-title: Ultra-Processed Foods, Diet Quality, and Health Using the NOVA Classification System – volume: 4 start-page: 847 year: 2001 end-page: 858 ident: bib118 article-title: Nutritional methods in the European Prospective Investigation of Cancer in Norfolk publication-title: Public Health Nutr. – volume: 144 start-page: e472 year: 2021 end-page: e487 ident: bib5 article-title: 2021 Dietary Guidance to Improve Cardiovascular Health: A Scientific Statement From the American Heart Association publication-title: Circulation – volume: 10 start-page: 497 year: 1990 end-page: 511 ident: bib71 article-title: Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease publication-title: Arteriosclerosis – volume: 68 start-page: 1180 year: 2019 end-page: 1189 ident: bib91 article-title: Population-level analysis of Blastocystis subtype prevalence and variation in the human gut microbiota publication-title: Gut – volume: 9 start-page: 357 year: 2012 end-page: 359 ident: bib96 article-title: Fast gapped-read alignment with Bowtie 2 publication-title: Nat. Methods – volume: 12 start-page: 2992 year: 2022 ident: bib43 article-title: Molecular Epidemiology of Blastocystis in Confined Slow Lorises, Macaques, and Gibbons publication-title: Animals (Basel) – year: 2022 ident: bib4 article-title: Cancer prevention recommendations – volume: 18 start-page: 171 year: 1992 end-page: 176 ident: bib111 article-title: When assessing twin concordance, use the probandwise not the pairwise rate publication-title: Schizophr. Bull. – year: 2024 ident: bib121 publication-title: Agricultural Research Service Food Surveys Research Group Home Page – volume: 535 start-page: 435 year: 2016 end-page: 439 ident: bib33 article-title: Mobile genes in the human microbiome are structured from global to individual scales publication-title: Nature – volume: 17 start-page: 261 year: 2020 end-page: 272 ident: bib125 article-title: SciPy 1.0: fundamental algorithms for scientific computing in Python publication-title: Nat. Methods – volume: 6 start-page: 648 year: 2015 end-page: 659 ident: bib74 article-title: Short sleep duration and dietary intake: epidemiologic evidence, mechanisms, and health implications publication-title: Adv. Nutr. – volume: 21 start-page: 5 year: 2018 end-page: 17 ident: bib55 article-title: The UN Decade of Nutrition, the NOVA food classification and the trouble with ultra-processing publication-title: Public Health Nutr. – volume: 154 start-page: 1089 year: 2001 end-page: 1099 ident: bib119 article-title: Comparative validation of the Block, Willett, and National Cancer Institute food frequency questionnaires: the Eating at America’s Table Study publication-title: Am. J. Epidemiol. – volume: 190 start-page: 1122 year: 2021 end-page: 1132 ident: bib23 article-title: Reproducibility and Validity of a Semiquantitative Food Frequency Questionnaire in Men Assessed by Multiple Methods publication-title: Am. J. Epidemiol. – volume: 614 start-page: 125 year: 2023 end-page: 135 ident: bib40 article-title: The person-to-person transmission landscape of the gut and oral microbiomes publication-title: Nature – volume: 15 year: 2022 ident: bib83 article-title: How the gut parasitome affects human health publication-title: Therap. Adv. Gastroenterol. – volume: 24 start-page: 133 year: 2018 end-page: 145.e5 ident: bib41 article-title: Mother-to-Infant Microbial Transmission from Different Body Sites Shapes the Developing Infant Gut Microbiome publication-title: Cell Host Microbe – volume: 3 start-page: 572 year: 2016 end-page: 584.e3 ident: bib48 article-title: Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome publication-title: Cell Syst. – volume: 11 year: 2015 ident: bib82 article-title: Are Human Intestinal Eukaryotes Beneficial or Commensals? publication-title: PLoS Pathog. – volume: 107 start-page: 14691 year: 2010 end-page: 14696 ident: bib112 article-title: Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa publication-title: Proc. Natl. Acad. Sci. USA – volume: 61 start-page: 714 year: 2015 end-page: 723 ident: bib64 article-title: GlycA: A Composite Nuclear Magnetic Resonance Biomarker of Systemic Inflammation publication-title: Clin. Chem. – volume: 158 start-page: 1313 year: 2020 end-page: 1325 ident: bib102 article-title: Association Between Sulfur-Metabolizing Bacterial Communities in Stool and Risk of Distal Colorectal Cancer in Men publication-title: Gastroenterology – volume: 393 start-page: 1958 year: 2019 end-page: 1972 ident: bib2 article-title: Health effects of dietary risks in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 publication-title: Lancet – volume: 7 start-page: 17 year: 2014 end-page: 44 ident: bib51 article-title: The impact of diet and lifestyle on gut microbiota and human health publication-title: Nutrients – volume: 10 start-page: 326 year: 2022 ident: bib14 article-title: Stool Microbiota Diversity Analysis of Blastocystis-Positive and Blastocystis-Negative Individuals publication-title: Microorganisms – volume: 10 year: 2021 ident: bib99 article-title: Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3 publication-title: eLife – volume: 30 start-page: 779 year: 2019 end-page: 790 ident: bib24 article-title: The Mind–Body Study: study design and reproducibility and interrelationships of psychosocial factors in the Nurses’ Health Study II publication-title: Cancer Causes Control – start-page: 92 year: 2010 end-page: 96 ident: bib127 article-title: Statsmodels: Econometric and statistical modeling with python publication-title: Proceedings of the 9th Python in Science Conference – year: 2022 ident: bib131 article-title: About adult BMI – volume: 54 start-page: 524 year: 2016 end-page: 528 ident: bib8 article-title: Blastocystis in Health and Disease: Are We Moving from a Clinical to a Public Health Perspective? publication-title: J. Clin. Microbiol. – volume: 69 start-page: 1258 year: 2020 end-page: 1268 ident: bib21 article-title: Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake publication-title: Gut – volume: 91 start-page: 55 year: 2023 ident: bib101 article-title: Improved Cardiometabolic Health Using a Personalised Nutrition Approach: The ZOE METHOD Study publication-title: Proc. AMIA Annu. Fall Symp. – volume: 505 start-page: 559 year: 2014 end-page: 563 ident: bib50 article-title: Diet rapidly and reproducibly alters the human gut microbiome publication-title: Nature – volume: 372 year: 2021 ident: bib110 article-title: Diversity and functional landscapes in the microbiota of animals in the wild publication-title: Science – volume: 101 start-page: 1717 year: 2007 end-page: 1719 ident: bib35 article-title: Prevalence of Blastocystis hominis and Strongyloides stercoralis infection in Okinawa, Japan publication-title: Parasitol. Res. – volume: 26 start-page: 666 year: 2019 end-page: 679.e7 ident: bib27 article-title: The Prevotella copri Complex Comprises Four Distinct Clades Underrepresented in Westernized Populations publication-title: Cell Host Microbe – volume: 3 year: 2014 ident: bib65 article-title: A novel protein glycan biomarker and future cardiovascular disease events publication-title: J. Am. Heart Assoc. – volume: 113 start-page: 569 year: 2013 end-page: 580 ident: bib122 article-title: Update of the Healthy Eating Index: HEI-2010 publication-title: J. Acad. Nutr. Diet. – volume: 146 start-page: 1564 year: 2014 end-page: 1572 ident: bib49 article-title: Diet and the intestinal microbiome: associations, functions, and implications for health and disease publication-title: Gastroenterology – volume: 45 start-page: 95 year: 2016 end-page: 97 ident: bib36 article-title: Prevalence and genetic diversity of Blastocystis in family units living in the United States publication-title: Infect. Genet. Evol. – volume: 11 start-page: 527 year: 2015 end-page: 538 ident: bib115 article-title: The gut microbiota of rural papua new guineans: composition, diversity patterns, and ecological processes publication-title: Cell Rep. – volume: 23 start-page: 924 year: 2017 end-page: 930 ident: bib90 article-title: How to: Establish and run a stool bank publication-title: Clin. Microbiol. Infect. – volume: 47 start-page: 11.12.1 year: 2014 end-page: 11.1234 ident: bib98 article-title: BEDTools: The Swiss-Army Tool for Genome Feature Analysis publication-title: Curr. Protoc. Bioinformatics – volume: 10 start-page: 5813 year: 2019 ident: bib63 article-title: Relationship between gut microbiota and circulating metabolites in population-based cohorts publication-title: Nat. Commun. – volume: 15 start-page: 80 year: 2022 ident: bib68 article-title: Interactions between Blastocystis subtype ST4 and gut microbiota in vitro publication-title: Parasit. Vectors – volume: 24 start-page: 109 year: 2023 end-page: 124 ident: bib76 article-title: Microbiome epidemiology and association studies in human health publication-title: Nat. Rev. Genet. – volume: 25 start-page: 2078 year: 2009 end-page: 2079 ident: bib97 article-title: The Sequence alignment/map (SAM) format and SAMtools publication-title: Bioinformatics – volume: 8 start-page: 62 year: 2020 ident: bib29 article-title: Multi-proxy analyses of a mid-15th century Middle Iron Age Bantu-speaker palaeo-faecal specimen elucidates the configuration of the “ancestral” sub-Saharan African intestinal microbiome publication-title: Microbiome – volume: 171 start-page: 275 year: 2020 end-page: 284 ident: bib31 article-title: Comparison of extraction methods for recovering ancient microbial DNA from paleofeces publication-title: Am. J. Phys. Anthropol. – volume: 117 start-page: 743 year: 2008 end-page: 753 ident: bib57 article-title: General cardiovascular risk profile for use in primary care: the Framingham Heart Study publication-title: Circulation – volume: 8 year: 2022 ident: bib11 article-title: An update on the distribution of Blastocystis subtypes in the Americas publication-title: Heliyon – volume: 3 start-page: 523 year: 2021 end-page: 529 ident: bib19 article-title: Postprandial glycaemic dips predict appetite and energy intake in healthy individuals publication-title: Nat. Metab. – volume: 302 start-page: 1993 year: 2009 end-page: 2000 ident: bib60 article-title: Major lipids, apolipoproteins, and risk of vascular disease publication-title: JAMA – volume: 185 start-page: E402 year: 2013 end-page: E408 ident: bib59 article-title: Serum C-peptide levels and risk of death among adults without diabetes mellitus publication-title: CMAJ – volume: 104 start-page: 13780 year: 2007 end-page: 13785 ident: bib15 article-title: Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases publication-title: Proc. Natl. Acad. Sci. USA – volume: 1 year: 2012 ident: bib58 article-title: Fasting serum C-peptide levels predict cardiovascular and overall death in nondiabetic adults publication-title: J. Am. Heart Assoc. – year: 2023 ident: bib128 article-title: funtimes: Functions for Time Series Analysis – volume: 70 start-page: 411 year: 2017 end-page: 422 ident: bib54 article-title: Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease in U.S. Adults publication-title: J. Am. Coll. Cardiol. – volume: 71 start-page: 2630 year: 2020 end-page: 2636 ident: bib92 article-title: Human Transmission of Blastocystis by Fecal Microbiota Transplantation Without Development of Gastrointestinal Symptoms in Recipients publication-title: Clin. Infect. Dis. – volume: 604 start-page: 732 year: 2022 end-page: 739 ident: bib108 article-title: Environmental factors shaping the gut microbiome in a Dutch population publication-title: Nature – volume: 111 start-page: E2329 year: 2014 end-page: E2338 ident: bib105 article-title: Relating the metatranscriptome and metagenome of the human gut publication-title: Proc. Natl. Acad. Sci. USA – volume: 34 start-page: 369 year: 2018 end-page: 377 ident: bib81 article-title: Associations between Gut Microbiota and Common Luminal Intestinal Parasites publication-title: Trends Parasitol. – volume: 140 start-page: e596 year: 2019 end-page: e646 ident: bib56 article-title: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines publication-title: Circulation – volume: 3 year: 2018 ident: bib94 article-title: Microbial Eukaryotes: a Missing Link in Gut Microbiome Studies publication-title: mSystems – volume: 36 start-page: 229 year: 2020 end-page: 232 ident: bib10 article-title: Pre-empting Pandora’s Box: Blastocystis Subtypes Revisited publication-title: Trends Parasitol. – volume: 41 start-page: 1633 year: 2023 end-page: 1644 ident: bib84 article-title: Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4 publication-title: Nat. Biotechnol. – volume: 65 start-page: 763 year: 2016 end-page: 771 ident: bib13 article-title: Current status of Blastocystis: A personal view publication-title: Parasitol. Int. – volume: 92 start-page: 22 year: 2004 end-page: 29 ident: bib34 article-title: Polymerase chain reaction-based genotype classification among human Blastocystis hominis populations isolated from different countries publication-title: Parasitol. Res. – volume: 175 start-page: 962 year: 2018 end-page: 972.e10 ident: bib52 article-title: US Immigration Westernizes the Human Gut Microbiome publication-title: Cell – year: 2022 ident: bib73 article-title: BMI Classification Percentile And Cut Off Points publication-title: StatPearls – volume: 3 start-page: 1026 year: 2018 ident: bib129 article-title: Pingouin: statistics in Python publication-title: J. Open Source Softw. – volume: 186 start-page: 3111 year: 2023 end-page: 3124.e13 ident: bib46 article-title: Ultra-deep sequencing of Hadza hunter-gatherers recovers vanishing gut microbes publication-title: Cell – volume: 6 start-page: 6505 year: 2015 ident: bib116 article-title: Subsistence strategies in traditional societies distinguish gut microbiomes publication-title: Nat. Commun. – volume: 486 start-page: 222 year: 2012 end-page: 227 ident: bib53 article-title: Human gut microbiome viewed across age and geography publication-title: Nature – volume: 43 start-page: 20A.1.1 year: 2016 end-page: 20A.1.8 ident: bib93 article-title: Blastocystis: Isolation, Xenic Cultivation, and Cryopreservation publication-title: Curr. Protoc. Microbiol. – volume: 126 start-page: 11 year: 2013 end-page: 18 ident: bib12 article-title: Variable geographic distribution of Blastocystis subtypes and its potential implications publication-title: Acta Trop. – volume: 176 start-page: 649 year: 2019 end-page: 662.e20 ident: bib85 article-title: Extensive Unexplored Human Microbiome Diversity Revealed by Over 150,000 Genomes from Metagenomes Spanning Age, Geography, and Lifestyle publication-title: Cell – volume: 5 start-page: 3654 year: 2014 ident: bib113 article-title: Gut microbiome of the Hadza hunter-gatherers publication-title: Nat. Commun. – volume: 25 start-page: 1682 year: 2015 end-page: 1693 ident: bib117 article-title: Metagenome Sequencing of the Hadza Hunter-Gatherer Gut Microbiota publication-title: Curr. Biol. – volume: 14 start-page: 1023 year: 2017 end-page: 1024 ident: bib25 article-title: Accessible, curated metagenomic data through ExperimentHub publication-title: Nat. Methods – volume: 8 year: 2020 ident: bib30 article-title: CoproID predicts the source of coprolites and paleofeces using microbiome composition and host DNA content publication-title: PeerJ – volume: 31 start-page: 5149 year: 2021 end-page: 5162.e6 ident: bib26 article-title: Hallstatt miners consumed blue cheese and beer during the Iron Age and retained a non-Westernized gut microbiome until the Baroque period publication-title: Curr. Biol. – volume: 452 start-page: 10 year: 2016 end-page: 17 ident: bib62 article-title: GlycA, a marker of acute phase glycoproteins, and the risk of incident type 2 diabetes mellitus: PREVEND study publication-title: Clin. Chim. Acta – volume: 14 start-page: 164 year: 2014 ident: bib37 article-title: Children of Senegal River Basin show the highest prevalence of Blastocystis sp. ever observed worldwide publication-title: BMC Infect. Dis. – volume: 40 start-page: 36 year: 2015 end-page: 39 ident: bib120 article-title: McCance and widdowson’s the composition of Foods Seventh summary edition and updated composition of foods integrated dataset publication-title: Nutr. Bull. – volume: 33 start-page: 1939 year: 2023 end-page: 1950.e4 ident: bib42 article-title: Maternal and food microbial sources shape the infant microbiome of a rural Ethiopian population publication-title: Curr. Biol. – volume: 135 start-page: 260 year: 2021 end-page: 282 ident: bib44 article-title: Blastocystis in domesticated and wild mammals and birds publication-title: Res. Vet. Sci. – volume: 80 start-page: 271 year: 2004 end-page: 278 ident: bib72 article-title: Visceral adipose tissue: relations between single-slice areas and total volume publication-title: Am. J. Clin. Nutr. – volume: 71 start-page: 620 year: 2018 end-page: 632 ident: bib66 article-title: Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke publication-title: J. Am. Coll. Cardiol. – volume: 367 start-page: 250 year: 2020 end-page: 251 ident: bib95 article-title: Are noncommunicable diseases communicable? publication-title: Science – volume: 26 start-page: 964 year: 2020 end-page: 973 ident: bib18 article-title: Human postprandial responses to food and potential for precision nutrition publication-title: Nat. Med. – volume: 375 start-page: 1634 year: 2010 end-page: 1639 ident: bib61 article-title: Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies publication-title: Lancet – year: 2020 ident: bib100 article-title: Personalised REsponses to DIetary Composition Trial (PREDICT): an intervention study to determine inter-individual differences in postprandial response to foods publication-title: Research Square – volume: 43 start-page: 348 year: 2005 end-page: 355 ident: bib80 article-title: Molecular phylogenies of Blastocystis isolates from different hosts: implications for genetic diversity, identification of species, and zoonosis publication-title: J. Clin. Microbiol. – volume: 594 start-page: 234 year: 2021 end-page: 239 ident: bib28 article-title: Reconstruction of ancient microbial genomes from the human gut publication-title: Nature – volume: 90 start-page: 326 year: 2014 end-page: 330 ident: bib88 article-title: The microbial eukaryote Blastocystis is a prevalent and diverse member of the healthy human gut microbiota publication-title: FEMS Microbiol. Ecol. – volume: 34 start-page: 77 year: 2013 end-page: 95 ident: bib1 article-title: Current evidence on healthy eating publication-title: Annu. Rev. Public Health – volume: 51 start-page: e295 year: 2022 end-page: e302 ident: bib109 article-title: Cohort Profile Update: Lifelines, a three-generation cohort study and biobank publication-title: Int. J. Epidemiol. – volume: 27 start-page: 321 year: 2021 end-page: 332 ident: bib7 article-title: Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals publication-title: Nat. Med. – volume: 71 start-page: 1302 year: 2022 end-page: 1314 ident: bib22 article-title: Stool microRNA profiles reflect different dietary and gut microbiome patterns in healthy individuals publication-title: Gut – volume: 16 start-page: 73 year: 2015 ident: bib106 article-title: Temporal and technical variability of human gut metagenomes publication-title: Genome Biol. – volume: 27 start-page: 333 year: 2021 end-page: 343 ident: bib103 article-title: The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk publication-title: Nat. Med. – volume: 31 start-page: 296 year: 2015 end-page: 299 ident: bib39 article-title: Prevalence and subtype analysis of Blastocystis in healthy Indian individuals publication-title: Infect. Genet. Evol. – volume: 22 start-page: 191 year: 2024 end-page: 205 ident: bib77 article-title: Machine learning for microbiologists publication-title: Nat. Rev. Microbiol. – start-page: 1 year: 2013 end-page: 32 ident: bib79 article-title: Chapter One - Recent Developments in Blastocystis Research publication-title: Advances in Parasitology – year: 2020 ident: bib3 article-title: Healthy diet – volume: 145 start-page: 1274 year: 2018 end-page: 1278 ident: bib38 article-title: The intestinal protist Blastocystis is not a common member of the healthy infant gut microbiota in a Westernized country (Ireland) publication-title: Parasitology – volume: 17 year: 2022 ident: bib104 article-title: Association of midlife antibiotic use with subsequent cognitive function in women publication-title: PLoS One – volume: 33 start-page: 925 year: 2017 end-page: 934 ident: bib89 article-title: Gut Protozoa: Friends or Foes of the Human Gut Microbiota? publication-title: Trends Parasitol. – volume: 490 start-page: 55 year: 2012 end-page: 60 ident: bib17 article-title: A metagenome-wide association study of gut microbiota in type 2 diabetes publication-title: Nature – volume: 17 start-page: 383 year: 2019 end-page: 390 ident: bib45 article-title: The ancestral and industrialized gut microbiota and implications for human health publication-title: Nat. Rev. Microbiol. – volume: 2 year: 2006 ident: bib107 article-title: Heritability of cardiovascular and personality traits in 6,148 Sardinians publication-title: PLoS Genet. – volume: 10 start-page: 4505 year: 2019 ident: bib47 article-title: Interplay between the human gut microbiome and host metabolism publication-title: Nat. Commun. – volume: 12 start-page: 641483 year: 2021 ident: bib67 article-title: Blastocystis Colonization Alters the Gut Microbiome and, in Some Cases, Promotes Faster Recovery From Induced Colitis publication-title: Front. Microbiol. – volume: 12 year: 2016 ident: bib78 article-title: Machine Learning Meta-analysis of Large Metagenomic Datasets: Tools and Biological Insights publication-title: PLoS Comput. Biol. – volume: 68 start-page: 2111 year: 2019 end-page: 2121 ident: bib86 article-title: International consensus conference on stool banking for faecal microbiota transplantation in clinical practice publication-title: Gut – year: 2010 ident: bib130 article-title: A healthy lifestyle – WHO recommendations – volume: 164 start-page: 497 year: 2013 end-page: 509 ident: bib32 article-title: Genetic diversity of blastocystis in livestock and zoo animals publication-title: Protist – volume: 129 start-page: S49 year: 2014 end-page: S73 ident: bib124 article-title: 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines publication-title: Circulation – volume: 11 start-page: 2848 year: 2017 end-page: 2863 ident: bib9 article-title: Large-scale comparative metagenomics of Blastocystis, a common member of the human gut microbiome publication-title: ISME J. – volume: 126 start-page: 1301 year: 2012 end-page: 1313 ident: bib70 article-title: Body fat distribution and risk of cardiovascular disease: an update publication-title: Circulation – volume: 318 start-page: 175 year: 2017 end-page: 193 ident: bib6 article-title: Behavioral Counseling to Promote a Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Known Cardiovascular Disease Risk Factors: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force publication-title: JAMA – volume: 1 year: 2015 ident: bib114 article-title: The microbiome of uncontacted Amerindians publication-title: Sci. Adv. – volume: 57 start-page: 289 year: 1995 end-page: 300 ident: bib126 article-title: Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing publication-title: J. R. Stat. Soc. B – volume: 128 start-page: 561 year: 2022 end-page: 568 ident: bib75 article-title: The emerging importance of tackling sleep-diet interactions in lifestyle interventions for weight management publication-title: Br. J. Nutr. – volume: 28 start-page: 1913 year: 2022 end-page: 1923 ident: bib87 article-title: Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases publication-title: Nat. Med. – volume: 25 start-page: 444 year: 2019 end-page: 453.e3 ident: bib20 article-title: Distinct Genetic and Functional Traits of Human Intestinal Prevotella copri Strains Are Associated with Different Habitual Diets publication-title: Cell Host Microbe – volume: 8 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib11 article-title: An update on the distribution of Blastocystis subtypes in the Americas publication-title: Heliyon doi: 10.1016/j.heliyon.2022.e12592 – volume: 28 start-page: 1913 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib87 article-title: Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases publication-title: Nat. Med. doi: 10.1038/s41591-022-01964-3 – volume: 31 start-page: 296 year: 2015 ident: 10.1016/j.cell.2024.06.018_bib39 article-title: Prevalence and subtype analysis of Blastocystis in healthy Indian individuals publication-title: Infect. Genet. Evol. doi: 10.1016/j.meegid.2015.02.012 – volume: 80 start-page: 271 year: 2004 ident: 10.1016/j.cell.2024.06.018_bib72 article-title: Visceral adipose tissue: relations between single-slice areas and total volume publication-title: Am. J. Clin. Nutr. doi: 10.1093/ajcn/80.2.271 – volume: 33 start-page: 1939 year: 2023 ident: 10.1016/j.cell.2024.06.018_bib42 article-title: Maternal and food microbial sources shape the infant microbiome of a rural Ethiopian population publication-title: Curr. Biol. doi: 10.1016/j.cub.2023.04.011 – ident: 10.1016/j.cell.2024.06.018_bib128 – volume: 41 start-page: 1633 year: 2023 ident: 10.1016/j.cell.2024.06.018_bib84 article-title: Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4 publication-title: Nat. Biotechnol. doi: 10.1038/s41587-023-01688-w – volume: 126 start-page: 11 year: 2013 ident: 10.1016/j.cell.2024.06.018_bib12 article-title: Variable geographic distribution of Blastocystis subtypes and its potential implications publication-title: Acta Trop. doi: 10.1016/j.actatropica.2012.12.011 – volume: 11 start-page: 2848 year: 2017 ident: 10.1016/j.cell.2024.06.018_bib9 article-title: Large-scale comparative metagenomics of Blastocystis, a common member of the human gut microbiome publication-title: ISME J. doi: 10.1038/ismej.2017.139 – volume: 61 start-page: 714 year: 2015 ident: 10.1016/j.cell.2024.06.018_bib64 article-title: GlycA: A Composite Nuclear Magnetic Resonance Biomarker of Systemic Inflammation publication-title: Clin. Chem. doi: 10.1373/clinchem.2014.232918 – volume: 91 start-page: 55 year: 2023 ident: 10.1016/j.cell.2024.06.018_bib101 article-title: Improved Cardiometabolic Health Using a Personalised Nutrition Approach: The ZOE METHOD Study publication-title: Proc. AMIA Annu. Fall Symp. – volume: 3 year: 2018 ident: 10.1016/j.cell.2024.06.018_bib94 article-title: Microbial Eukaryotes: a Missing Link in Gut Microbiome Studies publication-title: mSystems doi: 10.1128/mSystems.00201-17 – volume: 17 start-page: 261 year: 2020 ident: 10.1016/j.cell.2024.06.018_bib125 article-title: SciPy 1.0: fundamental algorithms for scientific computing in Python publication-title: Nat. Methods doi: 10.1038/s41592-019-0686-2 – volume: 175 start-page: 962 year: 2018 ident: 10.1016/j.cell.2024.06.018_bib52 article-title: US Immigration Westernizes the Human Gut Microbiome publication-title: Cell doi: 10.1016/j.cell.2018.10.029 – volume: 10 start-page: 497 year: 1990 ident: 10.1016/j.cell.2024.06.018_bib71 article-title: Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease publication-title: Arteriosclerosis doi: 10.1161/01.ATV.10.4.497 – volume: 535 start-page: 435 year: 2016 ident: 10.1016/j.cell.2024.06.018_bib33 article-title: Mobile genes in the human microbiome are structured from global to individual scales publication-title: Nature doi: 10.1038/nature18927 – volume: 146 start-page: 1564 year: 2014 ident: 10.1016/j.cell.2024.06.018_bib49 article-title: Diet and the intestinal microbiome: associations, functions, and implications for health and disease publication-title: Gastroenterology doi: 10.1053/j.gastro.2014.01.058 – year: 2020 ident: 10.1016/j.cell.2024.06.018_bib100 article-title: Personalised REsponses to DIetary Composition Trial (PREDICT): an intervention study to determine inter-individual differences in postprandial response to foods publication-title: Research Square – volume: 22 start-page: 191 year: 2024 ident: 10.1016/j.cell.2024.06.018_bib77 article-title: Machine learning for microbiologists publication-title: Nat. Rev. Microbiol. doi: 10.1038/s41579-023-00984-1 – volume: 47 start-page: 11.12.1 year: 2014 ident: 10.1016/j.cell.2024.06.018_bib98 article-title: BEDTools: The Swiss-Army Tool for Genome Feature Analysis publication-title: Curr. Protoc. Bioinformatics doi: 10.1002/0471250953.bi1112s47 – volume: 111 start-page: E2329 year: 2014 ident: 10.1016/j.cell.2024.06.018_bib105 article-title: Relating the metatranscriptome and metagenome of the human gut publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.1319284111 – volume: 3 start-page: 523 year: 2021 ident: 10.1016/j.cell.2024.06.018_bib19 article-title: Postprandial glycaemic dips predict appetite and energy intake in healthy individuals publication-title: Nat. Metab. doi: 10.1038/s42255-021-00383-x – volume: 10 year: 2021 ident: 10.1016/j.cell.2024.06.018_bib99 article-title: Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3 publication-title: eLife doi: 10.7554/eLife.65088 – volume: 27 start-page: 321 year: 2021 ident: 10.1016/j.cell.2024.06.018_bib7 article-title: Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals publication-title: Nat. Med. doi: 10.1038/s41591-020-01183-8 – volume: 31 start-page: 5149 year: 2021 ident: 10.1016/j.cell.2024.06.018_bib26 article-title: Hallstatt miners consumed blue cheese and beer during the Iron Age and retained a non-Westernized gut microbiome until the Baroque period publication-title: Curr. Biol. doi: 10.1016/j.cub.2021.09.031 – volume: 23 start-page: 924 year: 2017 ident: 10.1016/j.cell.2024.06.018_bib90 article-title: How to: Establish and run a stool bank publication-title: Clin. Microbiol. Infect. doi: 10.1016/j.cmi.2017.05.015 – volume: 8 year: 2020 ident: 10.1016/j.cell.2024.06.018_bib30 article-title: CoproID predicts the source of coprolites and paleofeces using microbiome composition and host DNA content publication-title: PeerJ doi: 10.7717/peerj.9001 – volume: 101 start-page: 1717 year: 2007 ident: 10.1016/j.cell.2024.06.018_bib35 article-title: Prevalence of Blastocystis hominis and Strongyloides stercoralis infection in Okinawa, Japan publication-title: Parasitol. Res. doi: 10.1007/s00436-007-0712-7 – volume: 25 start-page: 1948 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib16 article-title: Author Correction: Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation publication-title: Nat. Med. doi: 10.1038/s41591-019-0663-4 – volume: 3 year: 2014 ident: 10.1016/j.cell.2024.06.018_bib65 article-title: A novel protein glycan biomarker and future cardiovascular disease events publication-title: J. Am. Heart Assoc. – volume: 25 start-page: 1682 year: 2015 ident: 10.1016/j.cell.2024.06.018_bib117 article-title: Metagenome Sequencing of the Hadza Hunter-Gatherer Gut Microbiota publication-title: Curr. Biol. doi: 10.1016/j.cub.2015.04.055 – volume: 30 start-page: 779 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib24 article-title: The Mind–Body Study: study design and reproducibility and interrelationships of psychosocial factors in the Nurses’ Health Study II publication-title: Cancer Causes Control doi: 10.1007/s10552-019-01176-0 – volume: 367 start-page: 250 year: 2020 ident: 10.1016/j.cell.2024.06.018_bib95 article-title: Are noncommunicable diseases communicable? publication-title: Science doi: 10.1126/science.aaz3834 – volume: 1 year: 2012 ident: 10.1016/j.cell.2024.06.018_bib58 article-title: Fasting serum C-peptide levels predict cardiovascular and overall death in nondiabetic adults publication-title: J. Am. Heart Assoc. – volume: 505 start-page: 559 year: 2014 ident: 10.1016/j.cell.2024.06.018_bib50 article-title: Diet rapidly and reproducibly alters the human gut microbiome publication-title: Nature doi: 10.1038/nature12820 – volume: 107 start-page: 14691 year: 2010 ident: 10.1016/j.cell.2024.06.018_bib112 article-title: Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.1005963107 – volume: 129 start-page: S49 year: 2014 ident: 10.1016/j.cell.2024.06.018_bib124 article-title: 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines publication-title: Circulation doi: 10.1161/01.cir.0000437741.48606.98 – volume: 21 start-page: 5 year: 2018 ident: 10.1016/j.cell.2024.06.018_bib55 article-title: The UN Decade of Nutrition, the NOVA food classification and the trouble with ultra-processing publication-title: Public Health Nutr. doi: 10.1017/S1368980017000234 – volume: 15 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib83 article-title: How the gut parasitome affects human health publication-title: Therap. Adv. Gastroenterol. doi: 10.1177/17562848221091524 – volume: 10 start-page: 326 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib14 article-title: Stool Microbiota Diversity Analysis of Blastocystis-Positive and Blastocystis-Negative Individuals publication-title: Microorganisms doi: 10.3390/microorganisms10020326 – volume: 27 start-page: 333 year: 2021 ident: 10.1016/j.cell.2024.06.018_bib103 article-title: The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk publication-title: Nat. Med. doi: 10.1038/s41591-020-01223-3 – volume: 144 start-page: e472 year: 2021 ident: 10.1016/j.cell.2024.06.018_bib5 article-title: 2021 Dietary Guidance to Improve Cardiovascular Health: A Scientific Statement From the American Heart Association publication-title: Circulation doi: 10.1161/CIR.0000000000001031 – volume: 54 start-page: 524 year: 2016 ident: 10.1016/j.cell.2024.06.018_bib8 article-title: Blastocystis in Health and Disease: Are We Moving from a Clinical to a Public Health Perspective? publication-title: J. Clin. Microbiol. doi: 10.1128/JCM.02520-15 – volume: 10 start-page: 4505 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib47 article-title: Interplay between the human gut microbiome and host metabolism publication-title: Nat. Commun. doi: 10.1038/s41467-019-12476-z – volume: 36 start-page: 229 year: 2020 ident: 10.1016/j.cell.2024.06.018_bib10 article-title: Pre-empting Pandora’s Box: Blastocystis Subtypes Revisited publication-title: Trends Parasitol. doi: 10.1016/j.pt.2019.12.009 – volume: 12 year: 2016 ident: 10.1016/j.cell.2024.06.018_bib78 article-title: Machine Learning Meta-analysis of Large Metagenomic Datasets: Tools and Biological Insights publication-title: PLoS Comput. Biol. doi: 10.1371/journal.pcbi.1004977 – volume: 1 year: 2015 ident: 10.1016/j.cell.2024.06.018_bib114 article-title: The microbiome of uncontacted Amerindians publication-title: Sci. Adv. doi: 10.1126/sciadv.1500183 – volume: 614 start-page: 125 year: 2023 ident: 10.1016/j.cell.2024.06.018_bib40 article-title: The person-to-person transmission landscape of the gut and oral microbiomes publication-title: Nature doi: 10.1038/s41586-022-05620-1 – volume: 69 start-page: 1258 year: 2020 ident: 10.1016/j.cell.2024.06.018_bib21 article-title: Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake publication-title: Gut doi: 10.1136/gutjnl-2019-320438 – volume: 158 start-page: 1313 year: 2020 ident: 10.1016/j.cell.2024.06.018_bib102 article-title: Association Between Sulfur-Metabolizing Bacterial Communities in Stool and Risk of Distal Colorectal Cancer in Men publication-title: Gastroenterology doi: 10.1053/j.gastro.2019.12.029 – volume: 25 start-page: 444 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib20 article-title: Distinct Genetic and Functional Traits of Human Intestinal Prevotella copri Strains Are Associated with Different Habitual Diets publication-title: Cell Host Microbe doi: 10.1016/j.chom.2019.01.004 – volume: 3 start-page: 572 year: 2016 ident: 10.1016/j.cell.2024.06.018_bib48 article-title: Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome publication-title: Cell Syst. doi: 10.1016/j.cels.2016.10.004 – volume: 171 start-page: 275 year: 2020 ident: 10.1016/j.cell.2024.06.018_bib31 article-title: Comparison of extraction methods for recovering ancient microbial DNA from paleofeces publication-title: Am. J. Phys. Anthropol. doi: 10.1002/ajpa.23978 – volume: 24 start-page: 133 year: 2018 ident: 10.1016/j.cell.2024.06.018_bib41 article-title: Mother-to-Infant Microbial Transmission from Different Body Sites Shapes the Developing Infant Gut Microbiome publication-title: Cell Host Microbe doi: 10.1016/j.chom.2018.06.005 – volume: 45 start-page: 95 year: 2016 ident: 10.1016/j.cell.2024.06.018_bib36 article-title: Prevalence and genetic diversity of Blastocystis in family units living in the United States publication-title: Infect. Genet. Evol. doi: 10.1016/j.meegid.2016.08.018 – volume: 14 start-page: 1023 year: 2017 ident: 10.1016/j.cell.2024.06.018_bib25 article-title: Accessible, curated metagenomic data through ExperimentHub publication-title: Nat. Methods doi: 10.1038/nmeth.4468 – volume: 71 start-page: 1302 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib22 article-title: Stool microRNA profiles reflect different dietary and gut microbiome patterns in healthy individuals publication-title: Gut doi: 10.1136/gutjnl-2021-325168 – start-page: 92 year: 2010 ident: 10.1016/j.cell.2024.06.018_bib127 article-title: Statsmodels: Econometric and statistical modeling with python doi: 10.25080/Majora-92bf1922-011 – volume: 490 start-page: 55 year: 2012 ident: 10.1016/j.cell.2024.06.018_bib17 article-title: A metagenome-wide association study of gut microbiota in type 2 diabetes publication-title: Nature doi: 10.1038/nature11450 – volume: 43 start-page: 348 year: 2005 ident: 10.1016/j.cell.2024.06.018_bib80 article-title: Molecular phylogenies of Blastocystis isolates from different hosts: implications for genetic diversity, identification of species, and zoonosis publication-title: J. Clin. Microbiol. doi: 10.1128/JCM.43.1.348-355.2005 – volume: 17 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib104 article-title: Association of midlife antibiotic use with subsequent cognitive function in women publication-title: PLoS One doi: 10.1371/journal.pone.0264649 – volume: 34 start-page: 369 year: 2018 ident: 10.1016/j.cell.2024.06.018_bib81 article-title: Associations between Gut Microbiota and Common Luminal Intestinal Parasites publication-title: Trends Parasitol. doi: 10.1016/j.pt.2018.02.004 – volume: 604 start-page: 732 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib108 article-title: Environmental factors shaping the gut microbiome in a Dutch population publication-title: Nature doi: 10.1038/s41586-022-04567-7 – start-page: 1 year: 2013 ident: 10.1016/j.cell.2024.06.018_bib79 article-title: Chapter One - Recent Developments in Blastocystis Research doi: 10.1016/B978-0-12-407706-5.00001-0 – volume: 92 start-page: 22 year: 2004 ident: 10.1016/j.cell.2024.06.018_bib34 article-title: Polymerase chain reaction-based genotype classification among human Blastocystis hominis populations isolated from different countries publication-title: Parasitol. Res. doi: 10.1007/s00436-003-0995-2 – volume: 4 start-page: 847 year: 2001 ident: 10.1016/j.cell.2024.06.018_bib118 article-title: Nutritional methods in the European Prospective Investigation of Cancer in Norfolk publication-title: Public Health Nutr. doi: 10.1079/PHN2000102 – volume: 70 start-page: 411 year: 2017 ident: 10.1016/j.cell.2024.06.018_bib54 article-title: Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease in U.S. Adults publication-title: J. Am. Coll. Cardiol. doi: 10.1016/j.jacc.2017.05.047 – year: 2022 ident: 10.1016/j.cell.2024.06.018_bib73 article-title: BMI Classification Percentile And Cut Off Points – volume: 68 start-page: 1180 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib91 article-title: Population-level analysis of Blastocystis subtype prevalence and variation in the human gut microbiota publication-title: Gut doi: 10.1136/gutjnl-2018-316106 – volume: 8 start-page: 62 year: 2020 ident: 10.1016/j.cell.2024.06.018_bib29 article-title: Multi-proxy analyses of a mid-15th century Middle Iron Age Bantu-speaker palaeo-faecal specimen elucidates the configuration of the “ancestral” sub-Saharan African intestinal microbiome publication-title: Microbiome doi: 10.1186/s40168-020-00832-x – volume: 11 year: 2015 ident: 10.1016/j.cell.2024.06.018_bib82 article-title: Are Human Intestinal Eukaryotes Beneficial or Commensals? publication-title: PLoS Pathog. doi: 10.1371/journal.ppat.1005039 – volume: 186 start-page: 3111 year: 2023 ident: 10.1016/j.cell.2024.06.018_bib46 article-title: Ultra-deep sequencing of Hadza hunter-gatherers recovers vanishing gut microbes publication-title: Cell doi: 10.1016/j.cell.2023.05.046 – volume: 43 start-page: 20A.1.1 year: 2016 ident: 10.1016/j.cell.2024.06.018_bib93 article-title: Blastocystis: Isolation, Xenic Cultivation, and Cryopreservation publication-title: Curr. Protoc. Microbiol. doi: 10.1002/cpmc.18 – volume: 51 start-page: e295 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib109 article-title: Cohort Profile Update: Lifelines, a three-generation cohort study and biobank publication-title: Int. J. Epidemiol. doi: 10.1093/ije/dyab257 – volume: 12 start-page: 2992 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib43 article-title: Molecular Epidemiology of Blastocystis in Confined Slow Lorises, Macaques, and Gibbons publication-title: Animals (Basel) doi: 10.3390/ani12212992 – volume: 18 start-page: 171 year: 1992 ident: 10.1016/j.cell.2024.06.018_bib111 article-title: When assessing twin concordance, use the probandwise not the pairwise rate publication-title: Schizophr. Bull. doi: 10.1093/schbul/18.2.171 – volume: 164 start-page: 497 year: 2013 ident: 10.1016/j.cell.2024.06.018_bib32 article-title: Genetic diversity of blastocystis in livestock and zoo animals publication-title: Protist doi: 10.1016/j.protis.2013.05.003 – volume: 12 start-page: 641483 year: 2021 ident: 10.1016/j.cell.2024.06.018_bib67 article-title: Blastocystis Colonization Alters the Gut Microbiome and, in Some Cases, Promotes Faster Recovery From Induced Colitis publication-title: Front. Microbiol. doi: 10.3389/fmicb.2021.641483 – volume: 25 start-page: 2078 year: 2009 ident: 10.1016/j.cell.2024.06.018_bib97 article-title: The Sequence alignment/map (SAM) format and SAMtools publication-title: Bioinformatics doi: 10.1093/bioinformatics/btp352 – volume: 15 start-page: 80 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib68 article-title: Interactions between Blastocystis subtype ST4 and gut microbiota in vitro publication-title: Parasit. Vectors doi: 10.1186/s13071-022-05194-x – volume: 140 start-page: e596 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib56 article-title: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines publication-title: Circulation – volume: 185 start-page: E402 year: 2013 ident: 10.1016/j.cell.2024.06.018_bib59 article-title: Serum C-peptide levels and risk of death among adults without diabetes mellitus publication-title: CMAJ doi: 10.1503/cmaj.121950 – volume: 33 start-page: 925 year: 2017 ident: 10.1016/j.cell.2024.06.018_bib89 article-title: Gut Protozoa: Friends or Foes of the Human Gut Microbiota? publication-title: Trends Parasitol. doi: 10.1016/j.pt.2017.08.005 – volume: 11 start-page: 527 year: 2015 ident: 10.1016/j.cell.2024.06.018_bib115 article-title: The gut microbiota of rural papua new guineans: composition, diversity patterns, and ecological processes publication-title: Cell Rep. doi: 10.1016/j.celrep.2015.03.049 – volume: 16 start-page: 73 year: 2015 ident: 10.1016/j.cell.2024.06.018_bib106 article-title: Temporal and technical variability of human gut metagenomes publication-title: Genome Biol. doi: 10.1186/s13059-015-0639-8 – volume: 117 start-page: 743 year: 2008 ident: 10.1016/j.cell.2024.06.018_bib57 article-title: General cardiovascular risk profile for use in primary care: the Framingham Heart Study publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.107.699579 – volume: 302 start-page: 1993 year: 2009 ident: 10.1016/j.cell.2024.06.018_bib60 article-title: Major lipids, apolipoproteins, and risk of vascular disease publication-title: JAMA doi: 10.1001/jama.2009.1619 – year: 2010 ident: 10.1016/j.cell.2024.06.018_bib130 – volume: 40 start-page: 36 year: 2015 ident: 10.1016/j.cell.2024.06.018_bib120 article-title: McCance and widdowson’s the composition of Foods Seventh summary edition and updated composition of foods integrated dataset publication-title: Nutr. Bull. doi: 10.1111/nbu.12124 – volume: 34 start-page: 77 year: 2013 ident: 10.1016/j.cell.2024.06.018_bib1 article-title: Current evidence on healthy eating publication-title: Annu. Rev. Public Health doi: 10.1146/annurev-publhealth-031811-124646 – volume: 176 start-page: 649 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib85 article-title: Extensive Unexplored Human Microbiome Diversity Revealed by Over 150,000 Genomes from Metagenomes Spanning Age, Geography, and Lifestyle publication-title: Cell doi: 10.1016/j.cell.2019.01.001 – volume: 26 start-page: 666 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib27 article-title: The Prevotella copri Complex Comprises Four Distinct Clades Underrepresented in Westernized Populations publication-title: Cell Host Microbe doi: 10.1016/j.chom.2019.08.018 – volume: 7 start-page: 17 year: 2014 ident: 10.1016/j.cell.2024.06.018_bib51 article-title: The impact of diet and lifestyle on gut microbiota and human health publication-title: Nutrients doi: 10.3390/nu7010017 – volume: 17 start-page: 383 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib45 article-title: The ancestral and industrialized gut microbiota and implications for human health publication-title: Nat. Rev. Microbiol. doi: 10.1038/s41579-019-0191-8 – volume: 393 start-page: 1958 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib2 article-title: Health effects of dietary risks in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 publication-title: Lancet doi: 10.1016/S0140-6736(19)30041-8 – volume: 3 start-page: 1026 year: 2018 ident: 10.1016/j.cell.2024.06.018_bib129 article-title: Pingouin: statistics in Python publication-title: J. Open Source Softw. doi: 10.21105/joss.01026 – volume: 135 start-page: 260 year: 2021 ident: 10.1016/j.cell.2024.06.018_bib44 article-title: Blastocystis in domesticated and wild mammals and birds publication-title: Res. Vet. Sci. doi: 10.1016/j.rvsc.2020.09.031 – volume: 49 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib123 – volume: 594 start-page: 234 year: 2021 ident: 10.1016/j.cell.2024.06.018_bib28 article-title: Reconstruction of ancient microbial genomes from the human gut publication-title: Nature doi: 10.1038/s41586-021-03532-0 – volume: 126 start-page: 1301 year: 2012 ident: 10.1016/j.cell.2024.06.018_bib70 article-title: Body fat distribution and risk of cardiovascular disease: an update publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.111.067264 – volume: 9 start-page: 357 year: 2012 ident: 10.1016/j.cell.2024.06.018_bib96 article-title: Fast gapped-read alignment with Bowtie 2 publication-title: Nat. Methods doi: 10.1038/nmeth.1923 – volume: 104 start-page: 13780 year: 2007 ident: 10.1016/j.cell.2024.06.018_bib15 article-title: Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.0706625104 – volume: 145 start-page: 1274 year: 2018 ident: 10.1016/j.cell.2024.06.018_bib38 article-title: The intestinal protist Blastocystis is not a common member of the healthy infant gut microbiota in a Westernized country (Ireland) publication-title: Parasitology doi: 10.1017/S0031182018000033 – volume: 15 start-page: 312 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib69 article-title: Infection with pathogenic Blastocystis ST7 is associated with decreased bacterial diversity and altered gut microbiome profiles in diarrheal patients publication-title: Parasit. Vectors doi: 10.1186/s13071-022-05435-z – volume: 65 start-page: 763 year: 2016 ident: 10.1016/j.cell.2024.06.018_bib13 article-title: Current status of Blastocystis: A personal view publication-title: Parasitol. Int. doi: 10.1016/j.parint.2016.05.015 – volume: 486 start-page: 222 year: 2012 ident: 10.1016/j.cell.2024.06.018_bib53 article-title: Human gut microbiome viewed across age and geography publication-title: Nature doi: 10.1038/nature11053 – volume: 71 start-page: 2630 year: 2020 ident: 10.1016/j.cell.2024.06.018_bib92 article-title: Human Transmission of Blastocystis by Fecal Microbiota Transplantation Without Development of Gastrointestinal Symptoms in Recipients publication-title: Clin. Infect. Dis. doi: 10.1093/cid/ciz1122 – year: 2020 ident: 10.1016/j.cell.2024.06.018_bib3 – volume: 452 start-page: 10 year: 2016 ident: 10.1016/j.cell.2024.06.018_bib62 article-title: GlycA, a marker of acute phase glycoproteins, and the risk of incident type 2 diabetes mellitus: PREVEND study publication-title: Clin. Chim. Acta doi: 10.1016/j.cca.2015.11.001 – volume: 71 start-page: 620 year: 2018 ident: 10.1016/j.cell.2024.06.018_bib66 article-title: Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke publication-title: J. Am. Coll. Cardiol. doi: 10.1016/j.jacc.2017.12.006 – volume: 2 year: 2006 ident: 10.1016/j.cell.2024.06.018_bib107 article-title: Heritability of cardiovascular and personality traits in 6,148 Sardinians publication-title: PLoS Genet. doi: 10.1371/journal.pgen.0020132 – volume: 6 start-page: 6505 year: 2015 ident: 10.1016/j.cell.2024.06.018_bib116 article-title: Subsistence strategies in traditional societies distinguish gut microbiomes publication-title: Nat. Commun. doi: 10.1038/ncomms7505 – volume: 154 start-page: 1089 year: 2001 ident: 10.1016/j.cell.2024.06.018_bib119 article-title: Comparative validation of the Block, Willett, and National Cancer Institute food frequency questionnaires: the Eating at America’s Table Study publication-title: Am. J. Epidemiol. doi: 10.1093/aje/154.12.1089 – volume: 375 start-page: 1634 year: 2010 ident: 10.1016/j.cell.2024.06.018_bib61 article-title: Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies publication-title: Lancet doi: 10.1016/S0140-6736(10)60545-4 – year: 2022 ident: 10.1016/j.cell.2024.06.018_bib4 – volume: 190 start-page: 1122 year: 2021 ident: 10.1016/j.cell.2024.06.018_bib23 article-title: Reproducibility and Validity of a Semiquantitative Food Frequency Questionnaire in Men Assessed by Multiple Methods publication-title: Am. J. Epidemiol. doi: 10.1093/aje/kwaa280 – volume: 128 start-page: 561 year: 2022 ident: 10.1016/j.cell.2024.06.018_bib75 article-title: The emerging importance of tackling sleep-diet interactions in lifestyle interventions for weight management publication-title: Br. J. Nutr. doi: 10.1017/S000711452200160X – volume: 113 start-page: 569 year: 2013 ident: 10.1016/j.cell.2024.06.018_bib122 article-title: Update of the Healthy Eating Index: HEI-2010 publication-title: J. Acad. Nutr. Diet. doi: 10.1016/j.jand.2012.12.016 – year: 2024 ident: 10.1016/j.cell.2024.06.018_bib121 – volume: 372 year: 2021 ident: 10.1016/j.cell.2024.06.018_bib110 article-title: Diversity and functional landscapes in the microbiota of animals in the wild publication-title: Science doi: 10.1126/science.abb5352 – volume: 10 start-page: 5813 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib63 article-title: Relationship between gut microbiota and circulating metabolites in population-based cohorts publication-title: Nat. Commun. doi: 10.1038/s41467-019-13721-1 – volume: 318 start-page: 175 year: 2017 ident: 10.1016/j.cell.2024.06.018_bib6 publication-title: JAMA doi: 10.1001/jama.2017.3303 – volume: 57 start-page: 289 year: 1995 ident: 10.1016/j.cell.2024.06.018_bib126 article-title: Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing publication-title: J. R. Stat. Soc. B doi: 10.1111/j.2517-6161.1995.tb02031.x – year: 2022 ident: 10.1016/j.cell.2024.06.018_bib131 – volume: 6 start-page: 648 year: 2015 ident: 10.1016/j.cell.2024.06.018_bib74 article-title: Short sleep duration and dietary intake: epidemiologic evidence, mechanisms, and health implications publication-title: Adv. Nutr. doi: 10.3945/an.115.008623 – volume: 24 start-page: 109 year: 2023 ident: 10.1016/j.cell.2024.06.018_bib76 article-title: Microbiome epidemiology and association studies in human health publication-title: Nat. Rev. Genet. doi: 10.1038/s41576-022-00529-x – volume: 68 start-page: 2111 year: 2019 ident: 10.1016/j.cell.2024.06.018_bib86 article-title: International consensus conference on stool banking for faecal microbiota transplantation in clinical practice publication-title: Gut doi: 10.1136/gutjnl-2019-319548 – volume: 5 start-page: 3654 year: 2014 ident: 10.1016/j.cell.2024.06.018_bib113 article-title: Gut microbiome of the Hadza hunter-gatherers publication-title: Nat. Commun. doi: 10.1038/ncomms4654 – volume: 90 start-page: 326 year: 2014 ident: 10.1016/j.cell.2024.06.018_bib88 article-title: The microbial eukaryote Blastocystis is a prevalent and diverse member of the healthy human gut microbiota publication-title: FEMS Microbiol. Ecol. doi: 10.1111/1574-6941.12396 – volume: 26 start-page: 964 year: 2020 ident: 10.1016/j.cell.2024.06.018_bib18 article-title: Human postprandial responses to food and potential for precision nutrition publication-title: Nat. Med. doi: 10.1038/s41591-020-0934-0 – volume: 14 start-page: 164 year: 2014 ident: 10.1016/j.cell.2024.06.018_bib37 article-title: Children of Senegal River Basin show the highest prevalence of Blastocystis sp. ever observed worldwide publication-title: BMC Infect. Dis. doi: 10.1186/1471-2334-14-164 |
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| Title | Intestinal Blastocystis is linked to healthier diets and more favorable cardiometabolic outcomes in 56,989 individuals from 32 countries |
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