Health-related quality of life after isolated limb perfusion compared to extended resection, or amputation for locally advanced extremity sarcoma: Is a limb salvage strategy worth the effort?

• Published in: European journal of surgical oncology Vol. 48; no. 3; pp. 500 - 507
• Main Authors: Reijers, Sophie J.M., Husson, Olga, Soomers, Vicky L.M.N., Been, Lukas B., Bonenkamp, Johannes J., van de Sande, Michiel A.J., Verhoef, Cornelis, van der Graaf, Winette T.A., van Houdt, Winan J.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.03.2022
• Subjects: Amputation; Cross-Sectional Studies; Follow-Up Studies; Humans; Isolated limb perfusion; Limb Salvage - methods; Lower Extremity - surgery; Neoplasms, Second Primary - surgery; Perfusion; Quality of Life; Sarcoma - surgery; Soft Tissue Neoplasms - surgery; Soft tissue sarcoma; Treatment Outcome; Soft tissue sarcoma; Amputation; Quality of life; Isolated limb perfusion

The aim of this study was to compare long-term patient reported outcomes (PROs) in patients with locally advanced extremity soft tissue sarcoma (eSTS) after isolated limb perfusion followed by resection (IR), compared to extended resection (ER), primary amputation (A) or secondary amputation after I...