Transcriptional regulators of hepatic gluconeogenesis
Glucose is a primary fuel for generating energy in basic daily activities. Thus, glucose homeostasis is tightly regulated by counter-regulatory hormones such as glucagon, cortisol, and insulin, which affect key organs including liver, skeletal muscle, pancreas, and adipocytes. Among metabolic tissue...
Saved in:
Published in | Archives of pharmacal research Vol. 36; no. 2; pp. 189 - 200 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Heidelberg
Pharmaceutical Society of Korea
01.02.2013
대한약학회 |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Glucose is a primary fuel for generating energy in basic daily activities. Thus, glucose homeostasis is tightly regulated by counter-regulatory hormones such as glucagon, cortisol, and insulin, which affect key organs including liver, skeletal muscle, pancreas, and adipocytes. Among metabolic tissues, liver plays a critical role in controlling glucose production under various hormonal and metabolic cues. Under fasting, acute activation of both glycogenolysis and gluconeogenesis is achieved by post-translational modification or allosteric activation of key rate-limiting enzymes, thereby enabling enhanced glucose production from the liver to maintain glucose homeostasis. More prolonged fasting or starvation leads to the chronic activation of gluconeogenesis that requires increased expression of key enzymes in the pathway, which is turned off under feeding conditions by the molecular events that are initiated by insulin. This process is normally achieved by the regulation of gene expression at the level of transcription. Recently, the transcriptional regulators of hepatic gluconeogenesis are considered as potential therapeutic targets for the treatment of type 2 diabetes. In this review, we would like to discuss the current knowledge regarding the key transcriptional activators and inhibitors of hepatic gluconeogenic program to provide the better insight into the control of glycemia in the disease status. |
---|---|
AbstractList | Glucose is a primary fuel for generating energy in basic daily activities. Thus, glucose homeostasis is tightly regulated by counter-regulatory hormones such as glucagon, cortisol, and insulin, which affect key organs including liver, skeletal muscle, pancreas, and adipocytes. Among metabolic tissues, liver plays a critical role in controlling glucose production under various hormonal and metabolic cues. Under fasting, acute activation of both glycogenolysis and gluconeogenesis is achieved by post-translational modification or allosteric activation of key rate-limiting enzymes, thereby enabling enhanced glucose production from the liver to maintain glucose homeostasis. More prolonged fasting or starvation leads to the chronic activation of gluconeogenesis that requires increased expression of key enzymes in the pathway, which is turned off under feeding conditions by the molecular events that are initiated by insulin. This process is normally achieved by the regulation of gene expression at the level of transcription. Recently, the transcriptional regulators of hepatic gluconeogenesis are considered as potential therapeutic targets for the treatment of type 2 diabetes. In this review, we would like to discuss the current knowledge regarding the key transcriptional activators and inhibitors of hepatic gluconeogenic program to provide the better insight into the control of glycemia in the disease status. Glucose is a primary fuel for generating energyin basic daily activities. Thus, glucose homeostasis istightly regulated by counter-regulatory hormones such asglucagon, cortisol, and insulin, which affect key organsincluding liver, skeletal muscle, pancreas, and adipocytes. Among metabolic tissues, liver plays a critical role incontrolling glucose production under various hormonal andmetabolic cues. Under fasting, acute activation of bothglycogenolysis and gluconeogenesis is achieved by posttranslationalmodification or allosteric activation of keyrate-limiting enzymes, thereby enabling enhanced glucoseproduction from the liver to maintain glucose homeostasis. More prolonged fasting or starvation leads to the chronicactivation of gluconeogenesis that requires increasedexpression of key enzymes in the pathway, which is turnedoff under feeding conditions by the molecular events thatare initiated by insulin. This process is normally achievedby the regulation of gene expression at the level of transcription. Recently, the transcriptional regulators of hepaticgluconeogenesis are considered as potential therapeutictargets for the treatment of type 2 diabetes. In this review,we would like to discuss the current knowledge regardingthe key transcriptional activators and inhibitors of hepaticgluconeogenic program to provide the better insight intothe control of glycemia in the disease status. KCI Citation Count: 41 |
Author | Koo, Seung-Hoi Kim, Min-Jung Oh, Kyoung-Jin Han, Hye-Sook |
Author_xml | – sequence: 1 givenname: Kyoung-Jin surname: Oh fullname: Oh, Kyoung-Jin organization: Division of Biochemistry and Molecular Biology, Department of Molecular Cell Biology and Samsung Biomedical Institute, Sungkyunkwan University School of Medicine – sequence: 2 givenname: Hye-Sook surname: Han fullname: Han, Hye-Sook organization: Division of Biochemistry and Molecular Biology, Department of Molecular Cell Biology and Samsung Biomedical Institute, Sungkyunkwan University School of Medicine – sequence: 3 givenname: Min-Jung surname: Kim fullname: Kim, Min-Jung organization: Division of Biochemistry and Molecular Biology, Department of Molecular Cell Biology and Samsung Biomedical Institute, Sungkyunkwan University School of Medicine – sequence: 4 givenname: Seung-Hoi surname: Koo fullname: Koo, Seung-Hoi email: shkoo@skku.edu organization: Division of Biochemistry and Molecular Biology, Department of Molecular Cell Biology and Samsung Biomedical Institute, Sungkyunkwan University School of Medicine |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23361586$$D View this record in MEDLINE/PubMed https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001901422$$DAccess content in National Research Foundation of Korea (NRF) |
BookMark | eNp9kD1PwzAQhi1URD_gB7CgjjAYfHbsOGNV8VGpEhIqs-U6TkibxsFOBv49LimMTCfdPffe6ZmiUeMai9A1kHsgJH0IQGlKMQGGCQGJ-RmaQJYKzFIpRmhCKGdYUJGN0TSEHSFMcM4v0JgyJoBLMUF843UTjK_arnKNrufeln2tO-fD3BXzD9vqrjLzsu5NvO1K29hQhUt0Xug62KtTnaH3p8fN8gWvX59Xy8Uam4SQDksOic4ozU2m9VbHm5bkOTMaiKRG8ARMSvKEJsAZ4VmWpLEd51wzkCJN2QzdDbmNL9TeVMrp6qeWTu29WrxtVgqACSGO7O3Att599jZ06lAFY-tax7_7oIDKLJFAWRJRGFDjXQjeFqr11UH7LwVEHc2qwayKZtXRrOJx5-YU328PNv_b-FUZAToAIY6a0nq1c72PSsM_qd-QVYNI |
CitedBy_id | crossref_primary_10_1016_j_mce_2015_08_013 crossref_primary_10_3390_cells11142217 crossref_primary_10_3390_ijms150813938 crossref_primary_10_3389_fphar_2023_1115226 crossref_primary_10_2337_dbi22_0002 crossref_primary_10_3390_ijms22105159 crossref_primary_10_1038_s41598_021_81794_4 crossref_primary_10_2337_db13_1893 crossref_primary_10_1146_annurev_anthro_102317_045930 crossref_primary_10_1038_s41467_021_23624_9 crossref_primary_10_1371_journal_pone_0162397 crossref_primary_10_3390_ijms22147556 crossref_primary_10_3892_etm_2017_5602 crossref_primary_10_1074_jbc_M114_633990 crossref_primary_10_1016_j_carbpol_2020_116435 crossref_primary_10_1083_jcb_201607091 crossref_primary_10_1016_j_jes_2023_02_040 crossref_primary_10_1016_j_ejmech_2022_114171 crossref_primary_10_1038_s41401_020_00609_w crossref_primary_10_1590_1414_431x2022e11741 crossref_primary_10_1080_13813455_2016_1273364 crossref_primary_10_1002_ddr_22053 crossref_primary_10_1016_j_mce_2021_111264 crossref_primary_10_1016_j_bbrc_2016_12_125 crossref_primary_10_1016_j_ejphar_2021_174296 crossref_primary_10_1016_j_bcp_2021_114531 crossref_primary_10_1111_1744_7917_13130 crossref_primary_10_1080_02656736_2019_1623423 crossref_primary_10_1002_jcb_27706 crossref_primary_10_1016_j_celrep_2019_02_035 crossref_primary_10_1080_10641963_2016_1259332 crossref_primary_10_1177_14690667231179565 crossref_primary_10_1007_s12291_022_01064_6 crossref_primary_10_3389_fendo_2023_1081500 crossref_primary_10_1093_nar_gkw643 crossref_primary_10_2337_db16_0166 crossref_primary_10_3390_endocrines3010011 crossref_primary_10_3390_metabo14060336 crossref_primary_10_1186_s12986_019_0337_8 crossref_primary_10_1152_japplphysiol_00215_2023 crossref_primary_10_1016_j_ejmech_2022_114994 crossref_primary_10_1155_2014_961732 crossref_primary_10_1007_s41048_016_0031_6 crossref_primary_10_1016_j_cbpb_2023_110911 crossref_primary_10_1016_j_jsb_2017_02_006 crossref_primary_10_3390_ijms18081710 crossref_primary_10_3892_mmr_2018_9400 crossref_primary_10_1096_fj_201700002R crossref_primary_10_1530_JME_16_0218 crossref_primary_10_3390_genes15040503 crossref_primary_10_3390_ijms25137037 |
Cites_doi | 10.1016/0925-4773(96)00597-7 10.1016/S1097-2765(03)00134-5 10.1038/414799a 10.1074/jbc.M411487200 10.1038/35093131 10.1152/physrev.2001.81.3.1269 10.1038/370226a0 10.2337/diabetes.48.9.1885 10.1016/j.cell.2009.03.016 10.1016/j.cell.2004.09.013 10.1038/nature03967 10.1016/j.molcel.2008.09.013 10.1038/nm1044 10.2337/db07-0847 10.1126/science.1151363 10.1016/S0092-8674(00)82001-2 10.1093/nar/gki332 10.1146/annurev.nutr.27.061406.093618 10.1146/annurev.biochem.66.1.581 10.1038/ng1732 10.1016/j.tem.2005.03.010 10.1038/nm.2347 10.1074/jbc.M401138200 10.1016/j.ymgme.2004.07.018 10.1016/j.bbrc.2005.03.141 10.2337/db07-0381 10.1016/S0021-9258(17)37333-7 10.2337/db06-0860 10.1016/j.cmet.2009.10.007 10.1038/ng1960 10.1016/S0092-8674(00)81165-4 10.2337/db11-0548 10.1016/j.cmet.2006.06.008 10.1073/pnas.1012665107 10.1073/pnas.94.19.10215 10.1146/annurev.nu.11.070191.002341 10.1016/j.cmet.2009.01.007 10.1091/mbc.E05-06-0500 10.1038/370223a0 10.1016/j.cmet.2010.02.016 10.1038/nature07349 10.1042/0264-6021:3620513 10.1530/eje.0.1380240 10.1152/ajpendo.00158.2009 10.1126/science.272.5266.1336 10.1016/S0092-8674(00)80595-4 10.1016/S0074-7696(07)61003-1 10.1038/nature01667 10.1002/hep.25809 10.1146/annurev.nutr.17.1.405 10.1016/j.cmet.2007.08.006 10.1038/nrm3072 10.1016/j.cmet.2011.06.010 10.1016/j.molcel.2003.08.013 10.1126/science.286.5443.1368 10.1016/j.cell.2006.03.046 10.1038/nature10988 10.1016/j.cmet.2011.03.017 10.1371/journal.pgen.1002986 10.1038/382638a0 10.1073/pnas.0400593101 10.1016/j.cmet.2005.05.004 10.1016/S0092-8674(04)00126-6 10.1016/S1097-2765(03)00391-5 10.1074/jbc.M109.034660 10.1146/annurev.nutr.19.1.379 10.1007/s00125-007-0618-z 10.1007/s00125-006-0502-2 10.1146/annurev.bi.57.070188.003543 10.1126/science.1176639 10.1073/pnas.1932773100 10.1073/pnas.0914897107 10.1074/jbc.C110.175851 10.1507/endocrj.K07E-103 10.1038/sj.emboj.7600476 10.1038/ng829 10.1074/jbc.M111.315168 10.1016/j.cell.2006.10.018 10.1128/MCB.13.5.2822 10.1016/S0092-8674(00)81410-5 10.1126/science.275.5307.1790 10.1016/S0092-8674(00)80112-9 10.1007/s00125-011-2289-z 10.1038/384641a0 10.1002/gcc.20395 10.1038/35093050 10.1111/j.1600-0854.2007.00654.x 10.1074/jbc.M110.134890 10.1089/ars.2007.1796 10.1016/j.cmet.2007.12.009 10.1016/0092-8674(89)90013-5 10.1073/pnas.96.13.7421 10.1016/j.cell.2005.11.040 10.1038/365855a0 10.1016/j.metabol.2006.10.021 10.1016/j.molcel.2008.12.013 10.1016/S0092-8674(04)00452-0 10.1074/jbc.M509770200 10.1074/jbc.274.23.15982 10.1016/0092-8674(95)90199-X |
ContentType | Journal Article |
Copyright | The Pharmaceutical Society of Korea 2013 |
Copyright_xml | – notice: The Pharmaceutical Society of Korea 2013 |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 ACYCR |
DOI | 10.1007/s12272-013-0018-5 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic Korean Citation Index |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE MEDLINE - Academic |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Pharmacy, Therapeutics, & Pharmacology |
EISSN | 1976-3786 |
EndPage | 200 |
ExternalDocumentID | oai_kci_go_kr_ARTI_1136667 10_1007_s12272_013_0018_5 23361586 |
Genre | Research Support, Non-U.S. Gov't Journal Article Review |
GroupedDBID | --- -53 -56 -5G -BR -EM -Y2 -~C .86 .UV .VR 06C 06D 0R~ 0VY 1N0 2.D 203 23N 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2VQ 2WC 2~H 30V 3SX 4.4 406 408 40D 40E 53G 5GY 5VS 67N 67Z 6J9 6NX 8TC 8UJ 95- 95. 95~ 96X 9ZL AAAVM AABHQ AABYN AAFGU AAHNG AAIAL AAJKR AAKSU AANXM AANZL AAPBV AARHV AARTL AATNV AATVU AAUYE AAWCG AAYFA AAYIU AAYQN AAYTO ABDZT ABECU ABFGW ABFTV ABHQN ABJNI ABJOX ABKAS ABKCH ABMNI ABMQK ABNWP ABPLI ABQBU ABSXP ABTEG ABTKH ABTMW ABWNU ABXPI ACBMV ACBRV ACBXY ACBYP ACGFO ACGFS ACHSB ACHXU ACIGE ACIPQ ACKNC ACMDZ ACMLO ACOKC ACOMO ACREN ACSNA ACTTH ACUDM ACVWB ACWMK ADHHG ADHIR ADINQ ADKNI ADKPE ADMDM ADOXG ADRFC ADTPH ADURQ ADYFF ADYOE ADZKW AEBTG AEEQQ AEFTE AEGAL AEGNC AEJHL AEJRE AEKMD AENEX AEOHA AEPYU AESKC AESTI AETLH AEVLU AEVTX AEXYK AFAFS AFGCZ AFLOW AFNRJ AFQWF AFWTZ AFYQB AFZKB AGAYW AGDGC AGGBP AGGDS AGJBK AGKHE AGMZJ AGQMX AGWIL AGWZB AGYKE AHAVH AHBYD AHKAY AHSBF AHYZX AIAKS AIIXL AILAN AIMYW AITGF AJBLW AJDOV AJRNO AJZVZ AKMHD AKQUC ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMTXH AMXSW AMYLF AMYQR AOCGG ARMRJ ASPBG AVWKF AXYYD AZFZN B-. BA0 BBWZM BDATZ BGNMA C1A CAG COF CS3 CSCUP DDRTE DNIVK DPUIP EBLON EBS EIOEI EJD EMOBN ESBYG F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC G-Y G-Z GGCAI GGRSB GJIRD GNWQR GQ6 GQ7 GRRUI HF~ HG6 HMJXF HRMNR HVGLF HZ~ IJ- IKXTQ IWAJR IXC IXD I~X I~Z J-C J0Z JBSCW JZLTJ KOV KPH KVFHK LLZTM M4Y MA- MZR N2Q N9A NDZJH NF0 NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OVD P19 P2P PF0 PT4 PT5 QOK QOR QOS R89 R9I RHV RNI RNS ROL RPX RSV RZK S16 S1Z S26 S27 S28 S3A S3B SAP SBL SCLPG SDE SDH SHX SISQX SJN SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SZ9 SZN T13 T16 TEORI TSG TSK TUC U2A U9L UG4 UNUBA UOJIU UTJUX UZXMN VC2 VFIZW W48 WK6 WK8 YLTOR Z45 Z7U Z7V Z7W Z7X Z83 Z87 Z8O Z8P Z8Q Z91 ZMTXR ZOVNA ZZE ~A9 AACDK AAEOY AAHBH AAJBT AASML AAYZH ABAKF ACAOD ACDTI ACZOJ AEFQL AEMSY AFBBN AGQEE AGRTI AIGIU AJOOF CGR CUY CVF ECM EIF H13 NPM SJYHP AAYXX CITATION 7X8 ACYCR |
ID | FETCH-LOGICAL-c400t-8514a922dc9aaba361e0dd3ca1082c6541c70d42415305994782cd3c5a3186773 |
IEDL.DBID | AGYKE |
ISSN | 0253-6269 |
IngestDate | Tue Nov 21 21:39:35 EST 2023 Sat Aug 17 04:17:47 EDT 2024 Thu Sep 12 17:07:13 EDT 2024 Tue Oct 15 23:48:01 EDT 2024 Sat Dec 16 12:05:22 EST 2023 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 2 |
Keywords | Glucose metabolism Transcriptional co-activator Liver Transcriptional repressor Transcriptional activator |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c400t-8514a922dc9aaba361e0dd3ca1082c6541c70d42415305994782cd3c5a3186773 |
Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 G704-000010.2013.36.2.008 |
PMID | 23361586 |
PQID | 1289481234 |
PQPubID | 23479 |
PageCount | 12 |
ParticipantIDs | nrf_kci_oai_kci_go_kr_ARTI_1136667 proquest_miscellaneous_1289481234 crossref_primary_10_1007_s12272_013_0018_5 pubmed_primary_23361586 springer_journals_10_1007_s12272_013_0018_5 |
PublicationCentury | 2000 |
PublicationDate | 2013-02-01 |
PublicationDateYYYYMMDD | 2013-02-01 |
PublicationDate_xml | – month: 02 year: 2013 text: 2013-02-01 day: 01 |
PublicationDecade | 2010 |
PublicationPlace | Heidelberg |
PublicationPlace_xml | – name: Heidelberg – name: Korea (South) |
PublicationTitle | Archives of pharmacal research |
PublicationTitleAbbrev | Arch. Pharm. Res |
PublicationTitleAlternate | Arch Pharm Res |
PublicationYear | 2013 |
Publisher | Pharmaceutical Society of Korea 대한약학회 |
Publisher_xml | – name: Pharmaceutical Society of Korea – name: 대한약학회 |
References | Accili, Arden (CR1) 2004; 117 Lin, Handschin, Spiegelman (CR56) 2005; 1 Puigserver, Rhee, Donovan, Walkey, Yoon, Oriente, Kitamura, Altomonte, Dong, Accili, Spiegelman (CR75) 2003; 423 Behrens, Von Kries, Kuhl, Bruhn, Wedlich, Grosschedl, Birchmeier (CR13) 1996; 382 Aranda, Pascual (CR4) 2001; 81 Kim, Park, Lee, Park, Kim, Nedumaran, Jang, Cho, Ha, Lee, Lee, Choi (CR45) 2008; 57 Liu, Dentin, Chen, Hedrick, Ravnskjaer, Schenk, Milne, Meyers, Cole, Yates, Olefsky, Guarente, Montminy (CR58) 2008; 456 Koo, Satoh, Herzig, Lee, Hedrick, Kulkarni, Evans, Olefsky, Montminy (CR47) 2004; 10 Yi, Brubaker, Jin (CR99) 2005; 280 Chanda, Park, Choi (CR17) 2008; 55 Denboer, Hardy-Smith, Hogan, Cockram, Audas, Lu (CR27) 2005; 331 Motta, Divecha, Lemieux, Kamel, Chen, Gu, Bultsma, Mcburney, Guarente (CR63) 2004; 116 Lehman, Hunt, Leach, Hamlington, Arya, Abboud, Duggirala, Blangero, Goring, Stern (CR54) 2007; 56 Pilkis, Claus (CR71) 1991; 11 Vecchi, Montosi, Zhang, Lamberti, Duncan, Kaufman, Pietrangelo (CR90) 2009; 325 Tanaka, Naruse, Maekawa, Masuya, Shiroishi, Ishii (CR85) 1997; 94 He, Sabet, Djedjos, Miller, Sun, Hussain, Radovick, Wondisford (CR37) 2009; 137 Wallberg, Yamamura, Malik, Spiegelman, Roeder (CR92) 2003; 12 Wadzinski, Wheat, Jaspers, Peruski, Lickteig, Johnson, Klemm (CR91) 1993; 13 Molenaar, Van De Wetering, Oosterwegel, Peterson-Maduro, Godsave, Korinek, Roose, Destree, Clevers (CR61) 1996; 86 Norton, Fourcaudot, Abdul-Ghani, Winnier, Mehta, Jenkinson, Defronzo (CR67) 2011; 54 Kwok, Lundblad, Chrivia, Richards, Bachinger, Brennan, Roberts, Green, Goodman (CR49) 1994; 370 Kim, Ryu, Koh, Lee, Lim, Kim, Kim, Cho, Lee, Park, Koo, Choi (CR44) 2012; 287 Matsumoto, Pocai, Rossetti, Depinho, Accili (CR60) 2007; 6 Saltiel, Kahn (CR80) 2001; 414 Essers, Weijzen, De Vries-Smits, Saarloos, De Ruiter, Bos, Burgering (CR31) 2004; 23 Lee, Giannikopoulos, Duncan, Wang, Johansen, Brown, Plutzky, Hegele, Glimcher, Lee (CR50) 2011; 17 Yoon, Puigserver, Chen, Donovan, Wu, Rhee, Adelmant, Stafford, Kahn, Granner, Newgard, Spiegelman (CR100) 2001; 413 Altarejos, Montminy (CR3) 2011; 12 Towle, Kaytor, Shih (CR86) 1997; 17 Postic, Dentin, Denechaud, Girard (CR73) 2007; 27 Nordlie, Foster, Lange (CR66) 1999; 19 Ryu, Oh, Jo, Hedrick, Kim, Hwang, Park, Han, Choi, Montminy, Koo (CR78) 2009; 9 Lee, Seo, Song, Chanda, Kim, Kim, Lee, Ryu, Kim, Noh, Lee, Chiang, Koo, Choi (CR51) 2010; 285 Lee, Chanda, Yang, Oh, Kim, Yoon, Hong, Park, Lee, Choi, Hanson, Choi, Koo (CR52) 2010; 11 Puigserver, Wu, Park, Graves, Wright, Spiegelman (CR76) 1998; 92 Alberts, Arias, Hagiwara, Montminy, Feramisco (CR2) 1994; 269 Van Schaftingen, Gerin (CR89) 2002; 362 Brown, Goldstein (CR15) 2008; 7 Stirling, O’hare (CR83) 2006; 17 Zhang, Shen, Wu, Sakaki, Saunders, Rutkowski, Back, Kaufman (CR102) 2006; 124 Kim, Perdomo, Zhang, Slusher, Lee, Phillips, Fan, Giannoukakis, Gramignoli, Strom, Ringquist, Dong (CR43) 2011; 60 Barthel, Schmoll, Unterman (CR10) 2005; 16 Puigserver, Adelmant, Wu, Fan, Xu, O’malley, Spiegelman (CR74) 1999; 286 Conkright, Canettieri, Screaton, Guzman, Miraglia, Hogenesch, Montminy (CR24) 2003; 12 Yamauchi, Oike, Kamon, Waki, Komeda, Tsuchida, Date, Li, Miki, Akanuma, Nagai, Kimura, Saheki, Nakazato, Naitoh, Yamamura, Kadowaki (CR97) 2002; 30 Herzig, Long, Jhala, Hedrick, Quinn, Bauer, Rudolph, Schutz, Yoon, Puigserver, Spiegelman, Montminy (CR39) 2001; 413 Koo, Flechner, Qi, Zhang, Screaton, Jeffries, Hedrick, Xu, Boussouar, Brindle, Takemori, Montminy (CR46) 2005; 437 Moore, Connolly, Cherrington (CR62) 1998; 138 Uyeda, Repa (CR87) 2006; 4 Bedford, Kasper, Wang, Chang, Green, Brindle (CR11) 2011; 14 Lehtinen, Yuan, Boag, Yang, Villen, Becker, Dibacco, De La Iglesia, Gygi, Blackwell, Bonni (CR55) 2006; 125 Chin, Zhou, Wong, Lee, Chan, Qiang, Yuan, Ng, Jin (CR19) 2005; 33 Iourgenko, Zhang, Mickanin, Daly, Jiang, Hexham, Orth, Miraglia, Meltzer, Garza, Chirn, Mcwhinnie, Cohen, Skelton, Terry, Yu, Bodian, Buxton, Zhu, Song, Labow (CR41) 2003; 100 Helgason, Palsson, Thorleifsson, Grant, Emilsson, Gunnarsdottir, Adeyemo, Chen, Chen, Reynisdottir, Benediktsson, Hinney, Hansen, Andersen, Borch-Johnsen, Jorgensen, Schafer, Faruque, Doumatey, Zhou, Wilensky, Reilly, Rader, Bagger, Christiansen, Sigurdsson, Hebebrand, Pedersen, Thorsteinsdottir, Gulcher, Kong, Rotimi, Stefansson (CR38) 2007; 39 Chrivia, Kwok, Lamb, Hagiwara, Montminy, Goodman (CR22) 1993; 365 Nakae, Park, Accili (CR64) 1999; 274 Yamagata, Daitoku, Takahashi, Namiki, Hisatake, Kako, Mukai, Kasuya, Fukamizu (CR96) 2008; 32 Chandak, Janipalli, Bhaskar, Kulkarni, Mohankrishna, Hattersley, Frayling, Yajnik (CR18) 2007; 50 Bailey, Barreca, O’hare (CR7) 2007; 8 Bedford, Clarke (CR12) 2009; 33 Hayashi, Iwamoto, Kaku, Hirose, Maeda (CR36) 2007; 50 Nedumaran, Hong, Xie, Kim, Seo, Lee, Lee, Koo, Choi (CR65) 2009; 284 Panagopoulos, Moller, Dahlen, Isaksson, Mandahl, Vlamis-Gardikas, Mertens (CR70) 2007; 46 Wang, Li, Goode, Paz, Ouyang, Screaton, Fischer, Chen, Tabas, Montminy (CR94) 2012; 485 Mangelsdorf, Thummel, Beato, Herrlich, Schutz, Umesono, Blumberg, Kastner, Mark, Chambon, Evans (CR59) 1995; 83 Arias, Alberts, Brindle, Claret, Smeal, Karin, Feramisco, Montminy (CR5) 1994; 370 Lee, Chanda, Sim, Park, Choi (CR53) 2007; 261 Brunet, Bonni, Zigmond, Lin, Juo, Hu, Anderson, Arden, Blenis, Greenberg (CR16) 1999; 96 Haeusler, Kaestner, Accili (CR34) 2010; 285 Rubinfeld, Robbins, El-Gamil, Albert, Porfiri, Polakis (CR77) 1997; 275 Lin, Wu, Tarr, Lindenberg, St-Pierre, Zhang, Mootha, Jager, Vianna, Reznick, Cui, Manieri, Donovan, Wu, Cooper, Fan, Rohas, Zavacki, Cinti, Shulman, Lowell, Krainc, Spiegelman (CR57) 2004; 119 Shu, Sauter, Schulthess, Matveyenko, Oberholzer, Maedler (CR82) 2008; 57 Erion, Ignatova, Yonemitsu, Nagai, Chatterjee, Weismann, Hsiao, Zhang, Iwasaki, Stark, Flannery, Kahn, Carmean, Yu, Murray, Bhanot, Monia, Cline, Samuel, Shulman (CR30) 2009; 10 Oh, Park, Kim, Oh, Choi, Koo (CR69) 2012; 8 Iyer, Mccabe (CR42) 2004; 83 Ayala, Streeper, Desgrosellier, Durham, Suwanichkul, Svitek, Goldman, Barr, Powell, O’brien (CR6) 1999; 48 Zinker, Mika, Nguyen, Wilcox, Ohman, Von Geldern, Opgenorth, Jacobson (CR103) 2007; 56 Seol, Choi, Moore (CR81) 1996; 272 Daitoku, Hatta, Matsuzaki, Aratani, Ohshima, Miyagishi, Nakajima, Fukamizu (CR26) 2004; 101 Huber, Korn, Mclaughlin, Ohsugi, Herrmann, Kemler (CR40) 1996; 59 Hanson, Reshef (CR35) 1997; 66 Pilkis, El-Maghrabi, Claus (CR72) 1988; 57 Saberi, Bjelica, Schenk, Imamura, Bandyopadhyay, Li, Vargeese, Wang, Bowman, Zhang, Polisky, Olefsky (CR79) 2009; 297 Bailey, O’hare (CR8) 2007; 9 Bannister, Kouzarides (CR9) 1996; 384 Choi, KJ, Han, Yoon, Jung, Kim, Koo (CR20) 2012; 56 Wang, Inoue, Ravnskjaer, Viste, Miller, Liu, Hedrick, Vera, Montminy (CR93) 2010; 107 Takahashi, Daitoku, Hirota, Tamiya, Yokoyama, Kako, Nagashima, Nakamura, Shimada, Watanabe, Yamagata, Yasuda, Ishii, Fukamizu (CR84) 2011; 13 Yoon, Lee, Ryu, Kim, Ma, Seo, Kim, Kim, Lee, Hunter, Choi, Montminy, Koo (CR101) 2010; 107 Clevers (CR23) 2006; 127 Krones-Herzig, Mesaros, Metzger, Ziegler, Lemke, Bruning, Herzig (CR48) 2006; 281 Biggs, Meisenhelder, Hunter, Cavenee, Arden (CR14) 1999; 96 Dentin, Hedrick, Xie, Yates, Montminy (CR29) 2008; 319 Gonzalez, Montminy (CR32) 1989; 59 Van Der Horst, Tertoolen, De Vries-Smits, Frye, Medema, Burgering (CR88) 2004; 279 Choi, Oh, Koo (CR21) 2012 Ogryzko, Schiltz, Russanova, Howard, Nakatani (CR68) 1996; 87 Yao, Oh, Fuchs, Zhou, Ch’ng, Newsome, Bronson, Li, Livingston, Eckner (CR98) 1998; 93 Xu, Wang, Liu (CR95) 2012 Conkright, Guzman, Flechner, Su, Hogenesch, Montminy (CR25) 2003; 11 Grant, Thorleifsson, Reynisdottir, Benediktsson, Manolescu, Sainz, Helgason, Stefansson, Emilsson, Helgadottir, Styrkarsdottir, Magnusson, Walters, Palsdottir, Jonsdottir, Gudmundsdottir, Gylfason, Saemundsdottir, Wilensky, Reilly, Rader, Bagger, Christiansen, Gudnason, Sigurdsson, Thorsteinsdottir, Gulcher, Kong, Stefansson (CR33) 2006; 38 Y Wang (18_CR93) 2010; 107 M Matsumoto (18_CR60) 2007; 6 H Clevers (18_CR23) 2006; 127 TP Yao (18_CR98) 1998; 93 SF Grant (18_CR33) 2006; 38 D Choi (18_CR21) 2012 DC Bedford (18_CR11) 2011; 14 KT Chin (18_CR19) 2005; 33 RW Hanson (18_CR35) 1997; 66 JC Yoon (18_CR100) 2001; 413 D Bailey (18_CR7) 2007; 8 DJ Mangelsdorf (18_CR59) 1995; 83 YS Yoon (18_CR101) 2010; 107 J Nakae (18_CR64) 1999; 274 RC Nordlie (18_CR66) 1999; 19 SJ Pilkis (18_CR72) 1988; 57 Y Liu (18_CR58) 2008; 456 MD Conkright (18_CR24) 2003; 12 K Zhang (18_CR102) 2006; 124 C Vecchi (18_CR90) 2009; 325 A Barthel (18_CR10) 2005; 16 D Ryu (18_CR78) 2009; 9 M Molenaar (18_CR61) 1996; 86 VV Ogryzko (18_CR68) 1996; 87 AJ Bannister (18_CR9) 1996; 384 C Postic (18_CR73) 2007; 27 YD Kim (18_CR45) 2008; 57 P Puigserver (18_CR74) 1999; 286 MA Essers (18_CR31) 2004; 23 Y Wang (18_CR94) 2012; 485 RA Haeusler (18_CR34) 2010; 285 JH Lee (18_CR50) 2011; 17 LM Denboer (18_CR27) 2005; 331 DM Lehman (18_CR54) 2007; 56 H Daitoku (18_CR26) 2004; 101 SH Koo (18_CR46) 2005; 437 JC Chrivia (18_CR22) 1993; 365 F Yi (18_CR99) 2005; 280 J Behrens (18_CR13) 1996; 382 A Horst Van Der (18_CR88) 2004; 279 Y Tanaka (18_CR85) 1997; 94 MT Bedford (18_CR12) 2009; 33 W Seol (18_CR81) 1996; 272 DK Kim (18_CR44) 2012; 287 MD Conkright (18_CR25) 2003; 11 D Bailey (18_CR8) 2007; 9 JY Altarejos (18_CR3) 2011; 12 V Iourgenko (18_CR41) 2003; 100 MK Lehtinen (18_CR55) 2006; 125 K Uyeda (18_CR87) 2006; 4 Y Takahashi (18_CR84) 2011; 13 SJ Pilkis (18_CR71) 1991; 11 T Hayashi (18_CR36) 2007; 50 J Arias (18_CR5) 1994; 370 D Chanda (18_CR17) 2008; 55 B Zinker (18_CR103) 2007; 56 A Aranda (18_CR4) 2001; 81 T Yamauchi (18_CR97) 2002; 30 A Helgason (18_CR38) 2007; 39 AR Saltiel (18_CR80) 2001; 414 AK Iyer (18_CR42) 2004; 83 D Accili (18_CR1) 2004; 117 MS Brown (18_CR15) 2008; 7 YS Lee (18_CR53) 2007; 261 AS Alberts (18_CR2) 1994; 269 L Shu (18_CR82) 2008; 57 JM Lee (18_CR51) 2010; 285 B Rubinfeld (18_CR77) 1997; 275 L Norton (18_CR67) 2011; 54 GR Chandak (18_CR18) 2007; 50 J Lin (18_CR56) 2005; 1 DM Erion (18_CR30) 2009; 10 P Puigserver (18_CR75) 2003; 423 BE Wadzinski (18_CR91) 1993; 13 AE Wallberg (18_CR92) 2003; 12 JE Ayala (18_CR6) 1999; 48 MC Moore (18_CR62) 1998; 138 K Yamagata (18_CR96) 2008; 32 DH Kim (18_CR43) 2011; 60 I Panagopoulos (18_CR70) 2007; 46 A Krones-Herzig (18_CR48) 2006; 281 L He (18_CR37) 2009; 137 WH Biggs III (18_CR14) 1999; 96 A Brunet (18_CR16) 1999; 96 Z Xu (18_CR95) 2012 HC Towle (18_CR86) 1997; 17 MW Lee (18_CR52) 2010; 11 SH Koo (18_CR47) 2004; 10 J Stirling (18_CR83) 2006; 17 B Nedumaran (18_CR65) 2009; 284 O Huber (18_CR40) 1996; 59 M Saberi (18_CR79) 2009; 297 E Schaftingen Van (18_CR89) 2002; 362 KJ Oh (18_CR69) 2012; 8 P Puigserver (18_CR76) 1998; 92 J Lin (18_CR57) 2004; 119 MC Motta (18_CR63) 2004; 116 RP Kwok (18_CR49) 1994; 370 R Dentin (18_CR29) 2008; 319 S Herzig (18_CR39) 2001; 413 GA Gonzalez (18_CR32) 1989; 59 D Choi (18_CR20) 2012; 56 |
References_xml | – volume: 39 start-page: 218 year: 2007 end-page: 225 ident: CR38 article-title: Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution publication-title: Nature Genetics contributor: fullname: Stefansson – volume: 119 start-page: 121 year: 2004 end-page: 135 ident: CR57 article-title: Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice publication-title: Cell contributor: fullname: Spiegelman – volume: 60 start-page: 2763 year: 2011 end-page: 2774 ident: CR43 article-title: FoxO6 integrates insulin signaling with gluconeogenesis in the liver publication-title: Diabetes contributor: fullname: Dong – volume: 100 start-page: 12147 year: 2003 end-page: 12152 ident: CR41 article-title: Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells publication-title: Proceedings of the National Academy of Sciences of the United States of America contributor: fullname: Labow – volume: 46 start-page: 181 year: 2007 end-page: 191 ident: CR70 article-title: Characterization of the native CREB3L2 transcription factor and the FUS/CREB3L2 chimera publication-title: Genes, Chromosomes and Cancer contributor: fullname: Mertens – year: 2012 ident: CR95 article-title: Protein arginine methylation in hepatic glucose metabolism regulation: Histone, or non-histone? That is the question publication-title: Hepatology contributor: fullname: Liu – volume: 81 start-page: 1269 year: 2001 end-page: 1304 ident: CR4 article-title: Nuclear hormone receptors and gene expression publication-title: Physiological Reviews contributor: fullname: Pascual – volume: 8 start-page: 1796 year: 2007 end-page: 1814 ident: CR7 article-title: Trafficking of the bZIP transmembrane transcription factor CREB-H into alternate pathways of ERAD and stress-regulated intramembrane proteolysis publication-title: Traffic contributor: fullname: O’hare – volume: 19 start-page: 379 year: 1999 end-page: 406 ident: CR66 article-title: Regulation of glucose production by the liver publication-title: Annual Review of Nutrition contributor: fullname: Lange – volume: 10 start-page: 530 year: 2004 end-page: 534 ident: CR47 article-title: PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3 publication-title: Nature Medicine contributor: fullname: Montminy – volume: 281 start-page: 3025 year: 2006 end-page: 3029 ident: CR48 article-title: Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1 publication-title: Journal of Biological Chemistry contributor: fullname: Herzig – volume: 11 start-page: 1101 year: 2003 end-page: 1108 ident: CR25 article-title: Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness publication-title: Molecular Cell contributor: fullname: Montminy – volume: 284 start-page: 27511 year: 2009 end-page: 27523 ident: CR65 article-title: DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expression publication-title: Journal of Biological Chemistry contributor: fullname: Choi – volume: 325 start-page: 877 year: 2009 end-page: 880 ident: CR90 article-title: ER stress controls iron metabolism through induction of hepcidin publication-title: Science contributor: fullname: Pietrangelo – volume: 92 start-page: 829 year: 1998 end-page: 839 ident: CR76 article-title: A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis publication-title: Cell contributor: fullname: Spiegelman – volume: 9 start-page: 2305 year: 2007 end-page: 2321 ident: CR8 article-title: Transmembrane bZIP transcription factors in ER stress signaling and the unfolded protein response publication-title: Antioxidants & Redox Signaling contributor: fullname: O’hare – volume: 1 start-page: 361 year: 2005 end-page: 370 ident: CR56 article-title: Metabolic control through the PGC-1 family of transcription coactivators publication-title: Cell Metabolism contributor: fullname: Spiegelman – volume: 485 start-page: 128 year: 2012 end-page: 132 ident: CR94 article-title: Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes publication-title: Nature contributor: fullname: Montminy – volume: 413 start-page: 131 year: 2001 end-page: 138 ident: CR100 article-title: Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1 publication-title: Nature contributor: fullname: Spiegelman – volume: 7 start-page: 95 year: 2008 end-page: 96 ident: CR15 article-title: Selective versus total insulin resistance: a pathogenic paradox publication-title: Cell Metabolism contributor: fullname: Goldstein – volume: 66 start-page: 581 year: 1997 end-page: 611 ident: CR35 article-title: Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression publication-title: Annual Review of Biochemistry contributor: fullname: Reshef – volume: 57 start-page: 755 year: 1988 end-page: 783 ident: CR72 article-title: Hormonal regulation of hepatic gluconeogenesis and glycolysis publication-title: Annual Review of Biochemistry contributor: fullname: Claus – volume: 59 start-page: 3 year: 1996 end-page: 10 ident: CR40 article-title: Nuclear localization of beta-catenin by interaction with transcription factor LEF-1 publication-title: Mechanisms of Development contributor: fullname: Kemler – volume: 27 start-page: 179 year: 2007 end-page: 192 ident: CR73 article-title: ChREBP, a transcriptional regulator of glucose and lipid metabolism publication-title: Annual Review of Nutrition contributor: fullname: Girard – volume: 272 start-page: 1336 year: 1996 end-page: 1339 ident: CR81 article-title: An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors publication-title: Science contributor: fullname: Moore – volume: 297 start-page: E1137 issue: 5 year: 2009 end-page: E1146 ident: CR79 article-title: Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes publication-title: American Journal of Physiology, Endocrinology and Metabolism contributor: fullname: Olefsky – volume: 50 start-page: 63 year: 2007 end-page: 67 ident: CR18 article-title: Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population publication-title: Diabetologia contributor: fullname: Yajnik – volume: 437 start-page: 1109 year: 2005 end-page: 1111 ident: CR46 article-title: The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism publication-title: Nature contributor: fullname: Montminy – volume: 287 start-page: 21628 year: 2012 end-page: 21639 ident: CR44 article-title: Orphan nuclear receptor estrogen-related receptor gamma (ERRgamma) is key regulator of hepatic gluconeogenesis publication-title: Journal of Biological Chemistry contributor: fullname: Choi – volume: 56 start-page: 1546 issue: 4 year: 2012 end-page: 1556 ident: CR20 article-title: Protein arginine methyltransferase-1 regulates hepatic glucose production in a FoxO1 dependent manner publication-title: Hepatology contributor: fullname: Koo – volume: 83 start-page: 835 year: 1995 end-page: 839 ident: CR59 article-title: The nuclear receptor superfamily: The second decade publication-title: Cell contributor: fullname: Evans – volume: 413 start-page: 179 year: 2001 end-page: 183 ident: CR39 article-title: CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 publication-title: Nature contributor: fullname: Montminy – volume: 9 start-page: 240 year: 2009 end-page: 251 ident: CR78 article-title: TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1 publication-title: Cell Metabolism contributor: fullname: Koo – volume: 11 start-page: 465 year: 1991 end-page: 515 ident: CR71 article-title: Hepatic gluconeogenesis/glycolysis: regulation and structure/function relationships of substrate cycle enzymes publication-title: Annual Review of Nutrition contributor: fullname: Claus – volume: 16 start-page: 183 year: 2005 end-page: 189 ident: CR10 article-title: FoxO proteins in insulin action and metabolism publication-title: Trends in Endocrinology and Metabolism contributor: fullname: Unterman – volume: 138 start-page: 240 year: 1998 end-page: 248 ident: CR62 article-title: Autoregulation of hepatic glucose production publication-title: European Journal of Endocrinology contributor: fullname: Cherrington – volume: 423 start-page: 550 year: 2003 end-page: 555 ident: CR75 article-title: Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction publication-title: Nature contributor: fullname: Spiegelman – volume: 13 start-page: 505 year: 2011 end-page: 516 ident: CR84 article-title: Asymmetric arginine dimethylation determines life span in by regulating forkhead transcription factor DAF-16 publication-title: Cell Metabolism contributor: fullname: Fukamizu – volume: 107 start-page: 3087 year: 2010 end-page: 3092 ident: CR93 article-title: Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity publication-title: Proceedings of the National Academy of Sciences of the United States of America contributor: fullname: Montminy – volume: 86 start-page: 391 year: 1996 end-page: 399 ident: CR61 article-title: XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos publication-title: Cell contributor: fullname: Clevers – volume: 127 start-page: 469 year: 2006 end-page: 480 ident: CR23 article-title: Wnt/beta-catenin signaling in development and disease publication-title: Cell contributor: fullname: Clevers – volume: 362 start-page: 513 year: 2002 end-page: 532 ident: CR89 article-title: The glucose-6-phosphatase system publication-title: The Biochemical Journal contributor: fullname: Gerin – volume: 331 start-page: 113 year: 2005 end-page: 119 ident: CR27 article-title: Luman is capable of binding and activating transcription from the unfolded protein response element publication-title: Biochemical and Biophysical Research Communications contributor: fullname: Lu – volume: 6 start-page: 208 year: 2007 end-page: 216 ident: CR60 article-title: Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver publication-title: Cell Metabolism contributor: fullname: Accili – volume: 101 start-page: 10042 year: 2004 end-page: 10047 ident: CR26 article-title: Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity publication-title: Proceedings of the National Academy of Sciences of the United States of America contributor: fullname: Fukamizu – volume: 286 start-page: 1368 year: 1999 end-page: 1371 ident: CR74 article-title: Activation of PPARgamma coactivator-1 through transcription factor docking publication-title: Science contributor: fullname: Spiegelman – volume: 116 start-page: 551 year: 2004 end-page: 563 ident: CR63 article-title: Mammalian SIRT1 represses forkhead transcription factors publication-title: Cell contributor: fullname: Guarente – volume: 370 start-page: 226 year: 1994 end-page: 229 ident: CR5 article-title: Activation of cAMP and mitogen responsive genes relies on a common nuclear factor publication-title: Nature contributor: fullname: Montminy – volume: 280 start-page: 1457 year: 2005 end-page: 1464 ident: CR99 article-title: TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta publication-title: Journal of Biological Chemistry contributor: fullname: Jin – volume: 275 start-page: 1790 year: 1997 end-page: 1792 ident: CR77 article-title: Stabilization of beta-catenin by genetic defects in melanoma cell lines publication-title: Science contributor: fullname: Polakis – volume: 11 start-page: 331 year: 2010 end-page: 339 ident: CR52 article-title: Regulation of hepatic gluconeogenesis by an ER-bound transcription factor CREBH publication-title: Cell Metabolism contributor: fullname: Koo – volume: 54 start-page: 3132 year: 2011 end-page: 3142 ident: CR67 article-title: Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism publication-title: Diabetologia contributor: fullname: Defronzo – volume: 12 start-page: 141 year: 2011 end-page: 151 ident: CR3 article-title: CREB and the CRTC co-activators: sensors for hormonal and metabolic signals publication-title: Nature Reviews Molecular Cell Biology contributor: fullname: Montminy – volume: 38 start-page: 320 year: 2006 end-page: 323 ident: CR33 article-title: Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes publication-title: Nature Genetics contributor: fullname: Stefansson – volume: 285 start-page: 35245 year: 2010 end-page: 35248 ident: CR34 article-title: FoxOs function synergistically to promote glucose production publication-title: Journal of Biological Chemistry contributor: fullname: Accili – volume: 125 start-page: 987 year: 2006 end-page: 1001 ident: CR55 article-title: A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span publication-title: Cell contributor: fullname: Bonni – volume: 319 start-page: 1402 year: 2008 end-page: 1405 ident: CR29 article-title: Hepatic glucose sensing via the CREB coactivator CRTC2 publication-title: Science contributor: fullname: Montminy – volume: 93 start-page: 361 year: 1998 end-page: 372 ident: CR98 article-title: Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300 publication-title: Cell contributor: fullname: Eckner – volume: 382 start-page: 638 year: 1996 end-page: 642 ident: CR13 article-title: Functional interaction of beta-catenin with the transcription factor LEF-1 publication-title: Nature contributor: fullname: Birchmeier – volume: 8 start-page: e1002986 year: 2012 ident: CR69 article-title: TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver publication-title: PLoS Genetics contributor: fullname: Koo – volume: 12 start-page: 1137 year: 2003 end-page: 1149 ident: CR92 article-title: Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha publication-title: Molecular Cell contributor: fullname: Roeder – volume: 285 start-page: 32182 year: 2010 end-page: 32191 ident: CR51 article-title: AMPK-dependent repression of hepatic gluconeogenesis via disruption of CREB.CRTC2 complex by orphan nuclear receptor small heterodimer partner publication-title: Journal of Biological Chemistry contributor: fullname: Choi – volume: 274 start-page: 15982 year: 1999 end-page: 15985 ident: CR64 article-title: Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway publication-title: Journal of Biological Chemistry contributor: fullname: Accili – volume: 94 start-page: 10215 year: 1997 end-page: 10220 ident: CR85 article-title: Abnormal skeletal patterning in embryos lacking a single Cbp allele: A partial similarity with Rubinstein-Taybi syndrome publication-title: Proceedings of the National Academy of Sciences of the United States of America contributor: fullname: Ishii – volume: 55 start-page: 253 year: 2008 end-page: 268 ident: CR17 article-title: Molecular basis of endocrine regulation by orphan nuclear receptor Small Heterodimer Partner publication-title: Endocrine Journal contributor: fullname: Choi – volume: 117 start-page: 421 year: 2004 end-page: 426 ident: CR1 article-title: FoxOs at the crossroads of cellular metabolism, differentiation, and transformation publication-title: Cell contributor: fullname: Arden – volume: 83 start-page: 60 year: 2004 end-page: 73 ident: CR42 article-title: Molecular mechanisms of DAX1 action publication-title: Molecular Genetics and Metabolism contributor: fullname: Mccabe – volume: 30 start-page: 221 year: 2002 end-page: 226 ident: CR97 article-title: Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice publication-title: Nature Genetics contributor: fullname: Kadowaki – volume: 261 start-page: 117 year: 2007 end-page: 158 ident: CR53 article-title: Structure and function of the atypical orphan nuclear receptor small heterodimer partner publication-title: International Review of Cytology contributor: fullname: Choi – volume: 4 start-page: 107 year: 2006 end-page: 110 ident: CR87 article-title: Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis publication-title: Cell Metabolism contributor: fullname: Repa – year: 2012 ident: CR21 article-title: Involvement of multiple protein arginine methyltransferases in hepatic glucose metabolism publication-title: Hepatology contributor: fullname: Koo – volume: 17 start-page: 812 year: 2011 end-page: 815 ident: CR50 article-title: The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism publication-title: Nature Medicine contributor: fullname: Lee – volume: 13 start-page: 2822 year: 1993 end-page: 2834 ident: CR91 article-title: Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation publication-title: Molecular and Cellular Biology contributor: fullname: Klemm – volume: 107 start-page: 17704 year: 2010 end-page: 17709 ident: CR101 article-title: Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis publication-title: Proceedings of the National Academy of Sciences of the United States of America contributor: fullname: Koo – volume: 365 start-page: 855 year: 1993 end-page: 859 ident: CR22 article-title: Phosphorylated CREB binds specifically to the nuclear protein CBP publication-title: Nature contributor: fullname: Goodman – volume: 33 start-page: 1 year: 2009 end-page: 13 ident: CR12 article-title: Protein arginine methylation in mammals: who, what, and why publication-title: Molecular Cell contributor: fullname: Clarke – volume: 10 start-page: 499 year: 2009 end-page: 506 ident: CR30 article-title: Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein publication-title: Cell Metabolism contributor: fullname: Shulman – volume: 414 start-page: 799 year: 2001 end-page: 806 ident: CR80 article-title: Insulin signalling and the regulation of glucose and lipid metabolism publication-title: Nature contributor: fullname: Kahn – volume: 17 start-page: 413 year: 2006 end-page: 426 ident: CR83 article-title: CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P publication-title: Molecular Biology of the Cell contributor: fullname: O’hare – volume: 17 start-page: 405 year: 1997 end-page: 433 ident: CR86 article-title: Regulation of the expression of lipogenic enzyme genes by carbohydrate publication-title: Annual Review of Nutrition contributor: fullname: Shih – volume: 33 start-page: 1859 year: 2005 end-page: 1873 ident: CR19 article-title: The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinoma publication-title: Nucleic Acids Research contributor: fullname: Jin – volume: 384 start-page: 641 year: 1996 end-page: 643 ident: CR9 article-title: The CBP co-activator is a histone acetyltransferase publication-title: Nature contributor: fullname: Kouzarides – volume: 14 start-page: 219 year: 2011 end-page: 230 ident: CR11 article-title: Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control publication-title: Cell Metabolism contributor: fullname: Brindle – volume: 370 start-page: 223 year: 1994 end-page: 226 ident: CR49 article-title: Nuclear protein CBP is a coactivator for the transcription factor CREB publication-title: Nature contributor: fullname: Goodman – volume: 96 start-page: 857 year: 1999 end-page: 868 ident: CR16 article-title: Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor publication-title: Cell contributor: fullname: Greenberg – volume: 279 start-page: 28873 year: 2004 end-page: 28879 ident: CR88 article-title: FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1) publication-title: Journal of Biological Chemistry contributor: fullname: Burgering – volume: 57 start-page: 306 year: 2008 end-page: 314 ident: CR45 article-title: Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP publication-title: Diabetes contributor: fullname: Choi – volume: 57 start-page: 645 year: 2008 end-page: 653 ident: CR82 article-title: Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets publication-title: Diabetes contributor: fullname: Maedler – volume: 56 start-page: 380 year: 2007 end-page: 387 ident: CR103 article-title: Liver-selective glucocorticoid receptor antagonism decreases glucose production and increases glucose disposal, ameliorating insulin resistance publication-title: Metabolism contributor: fullname: Jacobson – volume: 56 start-page: 389 year: 2007 end-page: 393 ident: CR54 article-title: Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans publication-title: Diabetes contributor: fullname: Stern – volume: 137 start-page: 635 year: 2009 end-page: 646 ident: CR37 article-title: Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein publication-title: Cell contributor: fullname: Wondisford – volume: 124 start-page: 587 year: 2006 end-page: 599 ident: CR102 article-title: Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response publication-title: Cell contributor: fullname: Kaufman – volume: 96 start-page: 7421 year: 1999 end-page: 7426 ident: CR14 article-title: Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1 publication-title: Proceedings of the National Academy of Sciences of the United States of America contributor: fullname: Arden – volume: 12 start-page: 413 year: 2003 end-page: 423 ident: CR24 article-title: TORCs: Transducers of regulated CREB activity publication-title: Molecular Cell contributor: fullname: Montminy – volume: 269 start-page: 7623 year: 1994 end-page: 7630 ident: CR2 article-title: Recombinant cyclic AMP response element binding protein (CREB) phosphorylated on Ser-133 is transcriptionally active upon its introduction into fibroblast nuclei publication-title: Journal of Biological Chemistry contributor: fullname: Feramisco – volume: 456 start-page: 269 year: 2008 end-page: 273 ident: CR58 article-title: A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange publication-title: Nature contributor: fullname: Montminy – volume: 59 start-page: 675 year: 1989 end-page: 680 ident: CR32 article-title: Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133 publication-title: Cell contributor: fullname: Montminy – volume: 50 start-page: 980 year: 2007 end-page: 984 ident: CR36 article-title: Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population publication-title: Diabetologia contributor: fullname: Maeda – volume: 32 start-page: 221 year: 2008 end-page: 231 ident: CR96 article-title: Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt publication-title: Molecular Cell contributor: fullname: Fukamizu – volume: 48 start-page: 1885 year: 1999 end-page: 1889 ident: CR6 article-title: Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence publication-title: Diabetes contributor: fullname: O’brien – volume: 23 start-page: 4802 year: 2004 end-page: 4812 ident: CR31 article-title: FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK publication-title: EMBO Journal contributor: fullname: Burgering – volume: 87 start-page: 953 year: 1996 end-page: 959 ident: CR68 article-title: The transcriptional coactivators p300 and CBP are histone acetyltransferases publication-title: Cell contributor: fullname: Nakatani – volume: 59 start-page: 3 year: 1996 ident: 18_CR40 publication-title: Mechanisms of Development doi: 10.1016/0925-4773(96)00597-7 contributor: fullname: O Huber – volume: 11 start-page: 1101 year: 2003 ident: 18_CR25 publication-title: Molecular Cell doi: 10.1016/S1097-2765(03)00134-5 contributor: fullname: MD Conkright – volume: 414 start-page: 799 year: 2001 ident: 18_CR80 publication-title: Nature doi: 10.1038/414799a contributor: fullname: AR Saltiel – volume: 280 start-page: 1457 year: 2005 ident: 18_CR99 publication-title: Journal of Biological Chemistry doi: 10.1074/jbc.M411487200 contributor: fullname: F Yi – volume: 413 start-page: 179 year: 2001 ident: 18_CR39 publication-title: Nature doi: 10.1038/35093131 contributor: fullname: S Herzig – volume: 81 start-page: 1269 year: 2001 ident: 18_CR4 publication-title: Physiological Reviews doi: 10.1152/physrev.2001.81.3.1269 contributor: fullname: A Aranda – volume: 370 start-page: 226 year: 1994 ident: 18_CR5 publication-title: Nature doi: 10.1038/370226a0 contributor: fullname: J Arias – volume: 48 start-page: 1885 year: 1999 ident: 18_CR6 publication-title: Diabetes doi: 10.2337/diabetes.48.9.1885 contributor: fullname: JE Ayala – volume: 137 start-page: 635 year: 2009 ident: 18_CR37 publication-title: Cell doi: 10.1016/j.cell.2009.03.016 contributor: fullname: L He – volume: 119 start-page: 121 year: 2004 ident: 18_CR57 publication-title: Cell doi: 10.1016/j.cell.2004.09.013 contributor: fullname: J Lin – volume: 437 start-page: 1109 year: 2005 ident: 18_CR46 publication-title: Nature doi: 10.1038/nature03967 contributor: fullname: SH Koo – volume: 32 start-page: 221 year: 2008 ident: 18_CR96 publication-title: Molecular Cell doi: 10.1016/j.molcel.2008.09.013 contributor: fullname: K Yamagata – volume: 10 start-page: 530 year: 2004 ident: 18_CR47 publication-title: Nature Medicine doi: 10.1038/nm1044 contributor: fullname: SH Koo – volume: 57 start-page: 645 year: 2008 ident: 18_CR82 publication-title: Diabetes doi: 10.2337/db07-0847 contributor: fullname: L Shu – volume: 319 start-page: 1402 year: 2008 ident: 18_CR29 publication-title: Science doi: 10.1126/science.1151363 contributor: fullname: R Dentin – volume: 87 start-page: 953 year: 1996 ident: 18_CR68 publication-title: Cell doi: 10.1016/S0092-8674(00)82001-2 contributor: fullname: VV Ogryzko – volume: 33 start-page: 1859 year: 2005 ident: 18_CR19 publication-title: Nucleic Acids Research doi: 10.1093/nar/gki332 contributor: fullname: KT Chin – volume: 27 start-page: 179 year: 2007 ident: 18_CR73 publication-title: Annual Review of Nutrition doi: 10.1146/annurev.nutr.27.061406.093618 contributor: fullname: C Postic – volume: 66 start-page: 581 year: 1997 ident: 18_CR35 publication-title: Annual Review of Biochemistry doi: 10.1146/annurev.biochem.66.1.581 contributor: fullname: RW Hanson – volume: 38 start-page: 320 year: 2006 ident: 18_CR33 publication-title: Nature Genetics doi: 10.1038/ng1732 contributor: fullname: SF Grant – volume: 16 start-page: 183 year: 2005 ident: 18_CR10 publication-title: Trends in Endocrinology and Metabolism doi: 10.1016/j.tem.2005.03.010 contributor: fullname: A Barthel – volume: 17 start-page: 812 year: 2011 ident: 18_CR50 publication-title: Nature Medicine doi: 10.1038/nm.2347 contributor: fullname: JH Lee – volume: 279 start-page: 28873 year: 2004 ident: 18_CR88 publication-title: Journal of Biological Chemistry doi: 10.1074/jbc.M401138200 contributor: fullname: A Horst Van Der – volume: 83 start-page: 60 year: 2004 ident: 18_CR42 publication-title: Molecular Genetics and Metabolism doi: 10.1016/j.ymgme.2004.07.018 contributor: fullname: AK Iyer – volume: 331 start-page: 113 year: 2005 ident: 18_CR27 publication-title: Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2005.03.141 contributor: fullname: LM Denboer – volume: 57 start-page: 306 year: 2008 ident: 18_CR45 publication-title: Diabetes doi: 10.2337/db07-0381 contributor: fullname: YD Kim – volume: 269 start-page: 7623 year: 1994 ident: 18_CR2 publication-title: Journal of Biological Chemistry doi: 10.1016/S0021-9258(17)37333-7 contributor: fullname: AS Alberts – volume: 56 start-page: 389 year: 2007 ident: 18_CR54 publication-title: Diabetes doi: 10.2337/db06-0860 contributor: fullname: DM Lehman – volume: 10 start-page: 499 year: 2009 ident: 18_CR30 publication-title: Cell Metabolism doi: 10.1016/j.cmet.2009.10.007 contributor: fullname: DM Erion – volume: 39 start-page: 218 year: 2007 ident: 18_CR38 publication-title: Nature Genetics doi: 10.1038/ng1960 contributor: fullname: A Helgason – volume: 93 start-page: 361 year: 1998 ident: 18_CR98 publication-title: Cell doi: 10.1016/S0092-8674(00)81165-4 contributor: fullname: TP Yao – year: 2012 ident: 18_CR95 publication-title: Hepatology contributor: fullname: Z Xu – volume: 60 start-page: 2763 year: 2011 ident: 18_CR43 publication-title: Diabetes doi: 10.2337/db11-0548 contributor: fullname: DH Kim – volume: 4 start-page: 107 year: 2006 ident: 18_CR87 publication-title: Cell Metabolism doi: 10.1016/j.cmet.2006.06.008 contributor: fullname: K Uyeda – volume: 107 start-page: 17704 year: 2010 ident: 18_CR101 publication-title: Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.1012665107 contributor: fullname: YS Yoon – volume: 94 start-page: 10215 year: 1997 ident: 18_CR85 publication-title: Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.94.19.10215 contributor: fullname: Y Tanaka – volume: 11 start-page: 465 year: 1991 ident: 18_CR71 publication-title: Annual Review of Nutrition doi: 10.1146/annurev.nu.11.070191.002341 contributor: fullname: SJ Pilkis – volume: 9 start-page: 240 year: 2009 ident: 18_CR78 publication-title: Cell Metabolism doi: 10.1016/j.cmet.2009.01.007 contributor: fullname: D Ryu – volume: 17 start-page: 413 year: 2006 ident: 18_CR83 publication-title: Molecular Biology of the Cell doi: 10.1091/mbc.E05-06-0500 contributor: fullname: J Stirling – volume: 370 start-page: 223 year: 1994 ident: 18_CR49 publication-title: Nature doi: 10.1038/370223a0 contributor: fullname: RP Kwok – volume: 11 start-page: 331 year: 2010 ident: 18_CR52 publication-title: Cell Metabolism doi: 10.1016/j.cmet.2010.02.016 contributor: fullname: MW Lee – volume: 456 start-page: 269 year: 2008 ident: 18_CR58 publication-title: Nature doi: 10.1038/nature07349 contributor: fullname: Y Liu – volume: 362 start-page: 513 year: 2002 ident: 18_CR89 publication-title: The Biochemical Journal doi: 10.1042/0264-6021:3620513 contributor: fullname: E Schaftingen Van – volume: 138 start-page: 240 year: 1998 ident: 18_CR62 publication-title: European Journal of Endocrinology doi: 10.1530/eje.0.1380240 contributor: fullname: MC Moore – volume: 297 start-page: E1137 issue: 5 year: 2009 ident: 18_CR79 publication-title: American Journal of Physiology, Endocrinology and Metabolism doi: 10.1152/ajpendo.00158.2009 contributor: fullname: M Saberi – volume: 272 start-page: 1336 year: 1996 ident: 18_CR81 publication-title: Science doi: 10.1126/science.272.5266.1336 contributor: fullname: W Seol – volume: 96 start-page: 857 year: 1999 ident: 18_CR16 publication-title: Cell doi: 10.1016/S0092-8674(00)80595-4 contributor: fullname: A Brunet – volume: 261 start-page: 117 year: 2007 ident: 18_CR53 publication-title: International Review of Cytology doi: 10.1016/S0074-7696(07)61003-1 contributor: fullname: YS Lee – volume: 423 start-page: 550 year: 2003 ident: 18_CR75 publication-title: Nature doi: 10.1038/nature01667 contributor: fullname: P Puigserver – volume: 56 start-page: 1546 issue: 4 year: 2012 ident: 18_CR20 publication-title: Hepatology doi: 10.1002/hep.25809 contributor: fullname: D Choi – volume: 17 start-page: 405 year: 1997 ident: 18_CR86 publication-title: Annual Review of Nutrition doi: 10.1146/annurev.nutr.17.1.405 contributor: fullname: HC Towle – volume: 6 start-page: 208 year: 2007 ident: 18_CR60 publication-title: Cell Metabolism doi: 10.1016/j.cmet.2007.08.006 contributor: fullname: M Matsumoto – volume: 12 start-page: 141 year: 2011 ident: 18_CR3 publication-title: Nature Reviews Molecular Cell Biology doi: 10.1038/nrm3072 contributor: fullname: JY Altarejos – volume: 14 start-page: 219 year: 2011 ident: 18_CR11 publication-title: Cell Metabolism doi: 10.1016/j.cmet.2011.06.010 contributor: fullname: DC Bedford – volume: 12 start-page: 413 year: 2003 ident: 18_CR24 publication-title: Molecular Cell doi: 10.1016/j.molcel.2003.08.013 contributor: fullname: MD Conkright – volume: 286 start-page: 1368 year: 1999 ident: 18_CR74 publication-title: Science doi: 10.1126/science.286.5443.1368 contributor: fullname: P Puigserver – volume: 125 start-page: 987 year: 2006 ident: 18_CR55 publication-title: Cell doi: 10.1016/j.cell.2006.03.046 contributor: fullname: MK Lehtinen – volume: 485 start-page: 128 year: 2012 ident: 18_CR94 publication-title: Nature doi: 10.1038/nature10988 contributor: fullname: Y Wang – volume: 13 start-page: 505 year: 2011 ident: 18_CR84 publication-title: Cell Metabolism doi: 10.1016/j.cmet.2011.03.017 contributor: fullname: Y Takahashi – volume: 8 start-page: e1002986 year: 2012 ident: 18_CR69 publication-title: PLoS Genetics doi: 10.1371/journal.pgen.1002986 contributor: fullname: KJ Oh – volume: 382 start-page: 638 year: 1996 ident: 18_CR13 publication-title: Nature doi: 10.1038/382638a0 contributor: fullname: J Behrens – volume: 101 start-page: 10042 year: 2004 ident: 18_CR26 publication-title: Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.0400593101 contributor: fullname: H Daitoku – volume: 1 start-page: 361 year: 2005 ident: 18_CR56 publication-title: Cell Metabolism doi: 10.1016/j.cmet.2005.05.004 contributor: fullname: J Lin – volume: 116 start-page: 551 year: 2004 ident: 18_CR63 publication-title: Cell doi: 10.1016/S0092-8674(04)00126-6 contributor: fullname: MC Motta – volume: 12 start-page: 1137 year: 2003 ident: 18_CR92 publication-title: Molecular Cell doi: 10.1016/S1097-2765(03)00391-5 contributor: fullname: AE Wallberg – volume: 284 start-page: 27511 year: 2009 ident: 18_CR65 publication-title: Journal of Biological Chemistry doi: 10.1074/jbc.M109.034660 contributor: fullname: B Nedumaran – volume: 19 start-page: 379 year: 1999 ident: 18_CR66 publication-title: Annual Review of Nutrition doi: 10.1146/annurev.nutr.19.1.379 contributor: fullname: RC Nordlie – volume: 50 start-page: 980 year: 2007 ident: 18_CR36 publication-title: Diabetologia doi: 10.1007/s00125-007-0618-z contributor: fullname: T Hayashi – year: 2012 ident: 18_CR21 publication-title: Hepatology contributor: fullname: D Choi – volume: 50 start-page: 63 year: 2007 ident: 18_CR18 publication-title: Diabetologia doi: 10.1007/s00125-006-0502-2 contributor: fullname: GR Chandak – volume: 57 start-page: 755 year: 1988 ident: 18_CR72 publication-title: Annual Review of Biochemistry doi: 10.1146/annurev.bi.57.070188.003543 contributor: fullname: SJ Pilkis – volume: 325 start-page: 877 year: 2009 ident: 18_CR90 publication-title: Science doi: 10.1126/science.1176639 contributor: fullname: C Vecchi – volume: 100 start-page: 12147 year: 2003 ident: 18_CR41 publication-title: Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.1932773100 contributor: fullname: V Iourgenko – volume: 107 start-page: 3087 year: 2010 ident: 18_CR93 publication-title: Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.0914897107 contributor: fullname: Y Wang – volume: 285 start-page: 35245 year: 2010 ident: 18_CR34 publication-title: Journal of Biological Chemistry doi: 10.1074/jbc.C110.175851 contributor: fullname: RA Haeusler – volume: 55 start-page: 253 year: 2008 ident: 18_CR17 publication-title: Endocrine Journal doi: 10.1507/endocrj.K07E-103 contributor: fullname: D Chanda – volume: 23 start-page: 4802 year: 2004 ident: 18_CR31 publication-title: EMBO Journal doi: 10.1038/sj.emboj.7600476 contributor: fullname: MA Essers – volume: 30 start-page: 221 year: 2002 ident: 18_CR97 publication-title: Nature Genetics doi: 10.1038/ng829 contributor: fullname: T Yamauchi – volume: 287 start-page: 21628 year: 2012 ident: 18_CR44 publication-title: Journal of Biological Chemistry doi: 10.1074/jbc.M111.315168 contributor: fullname: DK Kim – volume: 127 start-page: 469 year: 2006 ident: 18_CR23 publication-title: Cell doi: 10.1016/j.cell.2006.10.018 contributor: fullname: H Clevers – volume: 13 start-page: 2822 year: 1993 ident: 18_CR91 publication-title: Molecular and Cellular Biology doi: 10.1128/MCB.13.5.2822 contributor: fullname: BE Wadzinski – volume: 92 start-page: 829 year: 1998 ident: 18_CR76 publication-title: Cell doi: 10.1016/S0092-8674(00)81410-5 contributor: fullname: P Puigserver – volume: 275 start-page: 1790 year: 1997 ident: 18_CR77 publication-title: Science doi: 10.1126/science.275.5307.1790 contributor: fullname: B Rubinfeld – volume: 86 start-page: 391 year: 1996 ident: 18_CR61 publication-title: Cell doi: 10.1016/S0092-8674(00)80112-9 contributor: fullname: M Molenaar – volume: 54 start-page: 3132 year: 2011 ident: 18_CR67 publication-title: Diabetologia doi: 10.1007/s00125-011-2289-z contributor: fullname: L Norton – volume: 384 start-page: 641 year: 1996 ident: 18_CR9 publication-title: Nature doi: 10.1038/384641a0 contributor: fullname: AJ Bannister – volume: 46 start-page: 181 year: 2007 ident: 18_CR70 publication-title: Genes, Chromosomes and Cancer doi: 10.1002/gcc.20395 contributor: fullname: I Panagopoulos – volume: 413 start-page: 131 year: 2001 ident: 18_CR100 publication-title: Nature doi: 10.1038/35093050 contributor: fullname: JC Yoon – volume: 8 start-page: 1796 year: 2007 ident: 18_CR7 publication-title: Traffic doi: 10.1111/j.1600-0854.2007.00654.x contributor: fullname: D Bailey – volume: 285 start-page: 32182 year: 2010 ident: 18_CR51 publication-title: Journal of Biological Chemistry doi: 10.1074/jbc.M110.134890 contributor: fullname: JM Lee – volume: 9 start-page: 2305 year: 2007 ident: 18_CR8 publication-title: Antioxidants & Redox Signaling doi: 10.1089/ars.2007.1796 contributor: fullname: D Bailey – volume: 7 start-page: 95 year: 2008 ident: 18_CR15 publication-title: Cell Metabolism doi: 10.1016/j.cmet.2007.12.009 contributor: fullname: MS Brown – volume: 59 start-page: 675 year: 1989 ident: 18_CR32 publication-title: Cell doi: 10.1016/0092-8674(89)90013-5 contributor: fullname: GA Gonzalez – volume: 96 start-page: 7421 year: 1999 ident: 18_CR14 publication-title: Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.96.13.7421 contributor: fullname: WH Biggs III – volume: 124 start-page: 587 year: 2006 ident: 18_CR102 publication-title: Cell doi: 10.1016/j.cell.2005.11.040 contributor: fullname: K Zhang – volume: 365 start-page: 855 year: 1993 ident: 18_CR22 publication-title: Nature doi: 10.1038/365855a0 contributor: fullname: JC Chrivia – volume: 56 start-page: 380 year: 2007 ident: 18_CR103 publication-title: Metabolism doi: 10.1016/j.metabol.2006.10.021 contributor: fullname: B Zinker – volume: 33 start-page: 1 year: 2009 ident: 18_CR12 publication-title: Molecular Cell doi: 10.1016/j.molcel.2008.12.013 contributor: fullname: MT Bedford – volume: 117 start-page: 421 year: 2004 ident: 18_CR1 publication-title: Cell doi: 10.1016/S0092-8674(04)00452-0 contributor: fullname: D Accili – volume: 281 start-page: 3025 year: 2006 ident: 18_CR48 publication-title: Journal of Biological Chemistry doi: 10.1074/jbc.M509770200 contributor: fullname: A Krones-Herzig – volume: 274 start-page: 15982 year: 1999 ident: 18_CR64 publication-title: Journal of Biological Chemistry doi: 10.1074/jbc.274.23.15982 contributor: fullname: J Nakae – volume: 83 start-page: 835 year: 1995 ident: 18_CR59 publication-title: Cell doi: 10.1016/0092-8674(95)90199-X contributor: fullname: DJ Mangelsdorf |
SSID | ssj0036555 |
Score | 2.3083026 |
SecondaryResourceType | review_article |
Snippet | Glucose is a primary fuel for generating energy in basic daily activities. Thus, glucose homeostasis is tightly regulated by counter-regulatory hormones such... Glucose is a primary fuel for generating energyin basic daily activities. Thus, glucose homeostasis istightly regulated by counter-regulatory hormones such... |
SourceID | nrf proquest crossref pubmed springer |
SourceType | Open Website Aggregation Database Index Database Publisher |
StartPage | 189 |
SubjectTerms | Animals Blood Glucose - metabolism Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - metabolism Gluconeogenesis - genetics Gluconeogenesis - physiology Humans Liver - metabolism Medicine Pharmacology/Toxicology Pharmacy Protein Processing, Post-Translational - genetics Regulatory Elements, Transcriptional - genetics Review Transcription, Genetic - physiology 약학 |
Title | Transcriptional regulators of hepatic gluconeogenesis |
URI | https://link.springer.com/article/10.1007/s12272-013-0018-5 https://www.ncbi.nlm.nih.gov/pubmed/23361586 https://search.proquest.com/docview/1289481234 https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001901422 |
Volume | 36 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
ispartofPNX | Archives of Pharmacal Research, 2013, 36(2), , pp.189-200 |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LT9tAEB4lQUK9QBtaal5yEeJA2SjZ9TrOMUKhtAjEgUhwWu3DpiiSg-zkAL-eGT8SVaGHnHywtevd2Z35dmfmG4ATHneTrtOSRQkXjBjlmJHOMY2HHs5NPDCOEoVvbsOrcfDnQT40gC-uLtJJp_ZIFop6mevGeZ-iCASjQnJMNmFDEt9XCzaGvx6vR7X-FaEsap2iMRcM4fqg9mV-1Mg_1qiZZslHQHPFSVrYnsvtMh8wLygLKeRk0pnPTMe-rRI6rjGsz7BVQVF_WK6dL9CI0zZs3lTO9jac3pW01q_n_v0ySys_90_9uyXh9esOyMLg1eoHm8zKAvfTLPenif83pqht6xfR8Wk8fSL1-px_hfHl6P7iilXlGJjFjT5jiM0CPeDc2YHWRouwF3edE1b3EEZYqidu-10XECQQxPoSIPiw-F5qUbDmiW_QSrGb7-AbqYNIuCg2xgVU4y5yPZ1IK6NEBkmiPTirxaJeStYNteRXphlTOGMUjxcp6cExCk5N7LMirmx6Pk3VJFN4IvitqGZNGPY9-FHLVeEGIq-IxhHPc4UGmhhruAg82C0FvuiTCxyljEIPftbSU9Uez___Q3trfb0Pn3ghfloFB9CaZfP4EIHOzBxVK_sImmM-fAd-s_I8 |
link.rule.ids | 315,786,790,27955,27956,41114,41556,42183,42625,52144,52267 |
linkProvider | Springer Nature |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LT9tAEB6VIEEvbaHQuk-DKg7AomQfjnNEFWl4BHEIEpxW-7ABRUoqOzmkv74ztrcRLT1w8sHWvmZ25rNm5huAbzxr521vFEtzLhgxyjGrvGcGf3o4t1nPeioUHl4mg2t5dqNumjruMmS7h5BkZamXxW6cdymNQDDqJMfUCqxKcvAtWD3-cXt-EgywSFTV7BS9uWCI13shmPnUII_c0cqkyJ9Cmv9ESSvn038No7DsOudkfDSf2SP36y9Gx2fu6w28asBofFxrzwa8yCabsDZswu2bsHdVE1svDuPRsk6rPIz34qsl5fXiLajK5QUDhEMWdYv7aVHG0zy-zyhv28VVfvwkm96RgX0ot-C6fzL6PmBNQwbm8KrPGKIzaXqce9czxhqRdLK298KZDgIJRx3FXbftJYECQbwvEuGHw_fKiIo3T2xDa4LTvIfYKiNT4dPMWi-py13qOyZXTqW5knluItgPctE_a94NvWRYphPTeGKUkZdqFcEuSk6P3YMmtmx63k31uND4T3CqqWtNknQj2AmC1XiFKC5icMfzUqOLJs4aLmQE72qJ_5mTC9ylSpMIDoL0dHPLy_8v6MOzvv4K64PR8EJfnF6ef4SXvFIF0ohP0JoV8-wzwp6Z_dKo-W8XUPUn |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV07T8MwED5RkBAL4k14BoQYoBatHafpiICKV6sOVGKzHDsGhJSipAz8e-7yoELAwJQhkZ3cnf1ddOfvAzjiScu1rJYsclwwYpRjsbSWafzp4TxOurGlg8L9QXg9Cm4f5WOlc5rX3e51SbI800AsTenk7M26s-nBN8471FIgGKnKMdmAOUJGCvERP6-3YhHKQvYUcV0wzNy7dVnztyG-AVMjzdxvOeePemkBQ70lWKzyR_-8dPgyzCTpCsz3qwr5ChwPSy7qj6b_MD1alTf9Y384Zan-WAVZoFS9Z-CQWalKP85yf-z854RarY1ftLSnyfiJ9sSXfA1GvauHi2tWaSgwg6tzwjChCnSXc2u6WsdahO2kZa0wuo3Yb0gE3HRaNiAcF0TVEmDGYPC-1KKguhPrMJviNJvgx1IHkbBREsc2IGG6yLa1k0ZGTgbOaQ9OagOqt5IqQ01JkcnaCq1NTXSRkh4coonVq3lRRHBN16exes0UpvE3ioRmwrDjwUHtAYVRT6UMjV_8nitEVaKZ4SLwYKN0zdecXOBXyij04LT2laoWZv73C2396-l9mB9e9tT9zeBuGxZ4EUUUTDswO8nek11MVCbxXhGMn0dT3LU |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Transcriptional+regulators+of+hepatic+gluconeogenesis&rft.jtitle=Archives+of+pharmacal+research&rft.au=Oh%2C+Kyoung-Jin&rft.au=Han%2C+Hye-Sook&rft.au=Kim%2C+Min-Jung&rft.au=Koo%2C+Seung-Hoi&rft.date=2013-02-01&rft.issn=0253-6269&rft.eissn=1976-3786&rft.volume=36&rft.issue=2&rft.spage=189&rft.epage=200&rft_id=info:doi/10.1007%2Fs12272-013-0018-5&rft.externalDBID=n%2Fa&rft.externalDocID=10_1007_s12272_013_0018_5 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0253-6269&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0253-6269&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0253-6269&client=summon |