Neurocognitive aspects of ketamine and esketamine on subjects with treatment-resistant depression: A comparative, randomized and double-blind study

• Published in: Psychiatry research Vol. 303; p. 114058
• Main Authors: Araújo-de-Freitas, Lucas, Santos-Lima, Cassio, Mendonça-Filho, Euclides, Vieira, Flávia, França, Ricardo J A F, Magnavita, Guilherme, Cardoso, Tanise L, Correia-Melo, Fernanda S, Leal, Gustavo C, Jesus-Nunes, Ana Paula, Souza-Marques, Breno, Marback, Roberta, Teles, Manuela, Echegaray, Mariana VF, Beanes, Graziele, Guerreiro-Costa, Lívia N F, Mello, Rodrigo P, Rabanea, Thaís, Lucchese, Ana Cecília, Abreu, Neander, Lacerda, Acioly L T, Quarantini, Lucas C
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.09.2021
• Subjects: Cognition; Depression; Esketamine; Executive functions; Ketamine; Esketamine; Depression; Executive functions; Cognition; Ketamine
• ISSN: 0165-1781; 1872-7123; 1872-7123
• DOI: 10.1016/j.psychres.2021.114058

•Ketamine and Esketamine improve cognition in depression.•Ketamine and Esketamine have similar effect on cognition in depression.•Low doses of Ketamine and Esketamine are cognitively safe in depression. The objective of this study is to evaluate cognition in patients using either ketamine or esketam...