Naloxone decreases the inhibitory effect of ethanol on the release of arginine-vasopressin induced by physical exercise in man

• Published in: Journal of Neural Transmission Vol. 116; no. 9; pp. 1065 - 1069
• Main Authors: Coiro, Vittorio, Casti, A., Volta, E., Melani, A., Maffei, M. L., Rubino, P., Vacca, P., Saccani-Jotti, G., Volpi, R., Chiodera, P.
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01.09.2009; Springer Nature B.V
• Subjects: Adult; Arginine Vasopressin - blood; Arginine Vasopressin - metabolism; Basic Neurosciences; Blood Pressure - drug effects; Carbon Dioxide - metabolism; Central Nervous System Depressants - pharmacology; Dose-Response Relationship, Drug; Ethanol - pharmacology; Exercise - physiology; Gene Expression Regulation - drug effects; Genetics and Immunology - Short Communication; Heart Rate - drug effects; Humans; Male; Medicine; Medicine & Public Health; Naloxone - pharmacology; Narcotic Antagonists - pharmacology; Neurology; Neurosciences; Oxygen Consumption - drug effects; Psychiatry; Pulmonary Ventilation - drug effects; Respiration - drug effects; Tidal Volume - drug effects; Time Factors; Young Adult; Physical exercise; Naloxone; Ethanol; Arginine-vasopressin

To establish whether ethanol and/or endogenous opioids play a role in the control of arginine-vasopressin (AVP) response to physical exercise, six healthy men underwent six bicycle-ergometer tests until exhaustion [exercise control test; exercise plus ethanol (50 of 110 ml proof whiskey orally), exe...