Clinical significance of changes in electrocardiographic R-wave voltage on chest leads in patients with acute anterior myocardial infarction
This article aims to clarify the clinical significance of changes in electrocardiographic (ECG) R-wave voltage on chest leads from 1 to 4 weeks in patients with acute anterior myocardial infarction (MI) in combination with echocardiographic findings and dual scintigraphic findings. Seventy-one patie...
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Published in | Journal of electrocardiology Vol. 35; no. 3; pp. 173 - 180 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Orlando, FL
Elsevier Inc
01.07.2002
Philadelphia, PA Churchill Livingstone Elsevier Science Ltd |
Subjects | |
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Abstract | This article aims to clarify the clinical significance of changes in electrocardiographic (ECG) R-wave voltage on chest leads from 1 to 4 weeks in patients with acute anterior myocardial infarction (MI) in combination with echocardiographic findings and dual scintigraphic findings. Seventy-one patients with acute anterior MI who underwent emergency revascularization were subjected to ECG and echocardiography, at both 1 and 4 weeks, and to thallium-201 (TI) and iodine-123-[beta ]-methyl-p-iodophenyl pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) about 1 week after the onset of MI. The total sum of ECG R-wave voltage on each chest lead was calculated. The mean defect ratio on TI and that on BMIPP derived from circumferential profile curve analysis were calculated. The percentage defect-discordant ratio of both SPECT images [(%) discordance on TI/BMIPP] was obtained. The percentage increase ratio of ECG R-wave voltage on chest leads [(%) increase of R wave] and the increase of left ventricular ejection fraction ([Delta ]EF) from 1 to 4 weeks were obtained. There were significant correlations between the (%) increase of R wave and the [Delta ]EF as well as between the (%) increase of R wave and the (%) discordance on TI/BMIPP (r = .63, P [lt ] .001; r = .74, P [lt ] .001). The reversibility of ECG R-wave voltage was related to cardiac functional improvement in addition to the discordance on the 2 images. Monitoring of changes in ECG R-wave voltage on chest leads is useful to detect the presence of myocardial viability and to evaluate functional evolution in patients with acute anterior MI. |
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AbstractList | This article aims to clarify the clinical significance of changes in electrocardiographic (ECG) R-wave voltage on chest leads from 1 to 4 weeks in patients with acute anterior myocardial infarction (MI) in combination with echocardiographic findings and dual scintigraphic findings. Seventy-one patients with acute anterior MI who underwent emergency revascularization were subjected to ECG and echocardiography, at both 1 and 4 weeks, and to thallium-201 (TI) and iodine-123-[beta ]-methyl-p-iodophenyl pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) about 1 week after the onset of MI. The total sum of ECG R-wave voltage on each chest lead was calculated. The mean defect ratio on TI and that on BMIPP derived from circumferential profile curve analysis were calculated. The percentage defect-discordant ratio of both SPECT images [(%) discordance on TI/BMIPP] was obtained. The percentage increase ratio of ECG R-wave voltage on chest leads [(%) increase of R wave] and the increase of left ventricular ejection fraction ([Delta ]EF) from 1 to 4 weeks were obtained. There were significant correlations between the (%) increase of R wave and the [Delta ]EF as well as between the (%) increase of R wave and the (%) discordance on TI/BMIPP (r = .63, P [lt ] .001; r = .74, P [lt ] .001). The reversibility of ECG R-wave voltage was related to cardiac functional improvement in addition to the discordance on the 2 images. Monitoring of changes in ECG R-wave voltage on chest leads is useful to detect the presence of myocardial viability and to evaluate functional evolution in patients with acute anterior MI. This article aims to clarify the clinical significance of changes in electrocardiographic (ECG) R-wave voltage on chest leads from 1 to 4 weeks in patients with acute anterior myocardial infarction (MI) in combination with echocardiographic findings and dual scintigraphic findings. Seventy-one patients with acute anterior MI who underwent emergency revascularization were subjected to ECG and echocardiography, at both 1 and 4 weeks, and to thallium-201 (TI) and iodine-123-beta-methyl-p-iodophenyl pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) about 1 week after the onset of MI. The total sum of ECG R-wave voltage on each chest lead was calculated. The mean defect ratio on TI and that on BMIPP derived from circumferential profile curve analysis were calculated. The percentage defect-discordant ratio of both SPECT images [(%) discordance on TI/BMIPP] was obtained. The percentage increase ratio of ECG R-wave voltage on chest leads [(%) increase of R wave] and the increase of left ventricular ejection fraction (DeltaEF) from 1 to 4 weeks were obtained. There were significant correlations between the (%) increase of R wave and the DeltaEF as well as between the (%) increase of R wave and the (%) discordance on TI/BMIPP (r =.63, P <.001; r =.74, P <.001). The reversibility of ECG R-wave voltage was related to cardiac functional improvement in addition to the discordance on the 2 images. Monitoring of changes in ECG R-wave voltage on chest leads is useful to detect the presence of myocardial viability and to evaluate functional evolution in patients with acute anterior MI. This article aims to clarify the clinical significance of changes in electrocardiographic (ECG) R-wave voltage on chest leads from 1 to 4 weeks in patients with acute anterior myocardial infarction (MI) in combination with echocardiographic findings and dual scintigraphic findings. Seventy-one patients with acute anterior MI who underwent emergency revascularization were subjected to ECG and echocardiography, at both 1 and 4 weeks, and to thallium-201 (TI) and iodine-123-beta-methyl-p-iodophenyl pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) about 1 week after the onset of MI. The total sum of ECG R-wave voltage on each chest lead was calculated. The mean defect ratio on TI and that on BMIPP derived from circumferential profile curve analysis were calculated. The percentage defect-discordant ratio of both SPECT images [(%) discordance on TI/BMIPP] was obtained. The percentage increase ratio of ECG R-wave voltage on chest leads [(%) increase of R wave] and the increase of left ventricular ejection fraction (DeltaEF) from 1 to 4 weeks were obtained. There were significant correlations between the (%) increase of R wave and the DeltaEF as well as between the (%) increase of R wave and the (%) discordance on TI/BMIPP (r =.63, P <.001; r =.74, P <.001). The reversibility of ECG R-wave voltage was related to cardiac functional improvement in addition to the discordance on the 2 images. Monitoring of changes in ECG R-wave voltage on chest leads is useful to detect the presence of myocardial viability and to evaluate functional evolution in patients with acute anterior MI. |
Author | Izawa, Hideo Tanahashi, Yoshifumi Kondo, Takahisa Ando, Akitada Nanasato, Mamoru Yokota, Mitsuhiro Saito, Hidehiko Isobe, Satoshi Okada, Mitsuhiro Nonokawa, Makoto Hirai, Makoto |
Author_xml | – sequence: 1 givenname: Satoshi surname: Isobe fullname: Isobe, Satoshi – sequence: 2 givenname: Mitsuhiro surname: Okada fullname: Okada, Mitsuhiro organization: From the Division of Cardiology, First Department of Internal Medicine, Nagoya University Graduate School of Medicine; Cardiovascular Division, Department of Clinical Pathophysiology, Nagoya University Graduate School of Medicine; and [dagger]Division of Cardiology, Nagoya Ekisaikai Hospital, Nagoya, Japan – sequence: 3 givenname: Akitada surname: Ando fullname: Ando, Akitada – sequence: 4 givenname: Mamoru surname: Nanasato fullname: Nanasato, Mamoru – sequence: 5 givenname: Makoto surname: Nonokawa fullname: Nonokawa, Makoto – sequence: 6 givenname: Hideo surname: Izawa fullname: Izawa, Hideo – sequence: 7 givenname: Takahisa surname: Kondo fullname: Kondo, Takahisa – sequence: 8 givenname: Makoto surname: Hirai fullname: Hirai, Makoto – sequence: 9 givenname: Mitsuhiro surname: Yokota fullname: Yokota, Mitsuhiro organization: From the Division of Cardiology, First Department of Internal Medicine, Nagoya University Graduate School of Medicine; Cardiovascular Division, Department of Clinical Pathophysiology, Nagoya University Graduate School of Medicine; and [dagger]Division of Cardiology, Nagoya Ekisaikai Hospital, Nagoya, Japan – sequence: 10 givenname: Yoshifumi surname: Tanahashi fullname: Tanahashi, Yoshifumi organization: From the Division of Cardiology, First Department of Internal Medicine, Nagoya University Graduate School of Medicine; Cardiovascular Division, Department of Clinical Pathophysiology, Nagoya University Graduate School of Medicine; and [dagger]Division of Cardiology, Nagoya Ekisaikai Hospital, Nagoya, Japan – sequence: 11 givenname: Hidehiko surname: Saito fullname: Saito, Hidehiko |
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Keywords | Human R wave Prognosis Infarct Acute Variability Cardiovascular disease Anterior infarct Coronary heart disease Myocardial disease Electrodiagnosis Electrocardiography Myocardium |
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SubjectTerms | Biological and medical sciences Cardiology. Vascular system Coronary heart disease Echocardiography Electrocardiography Fatty Acids Female Heart Humans Iodobenzenes Male Medical sciences Middle Aged Myocardial Infarction - physiopathology Thallium Radioisotopes Tomography, Emission-Computed, Single-Photon |
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Title | Clinical significance of changes in electrocardiographic R-wave voltage on chest leads in patients with acute anterior myocardial infarction |
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