Development and In Vivo Preclinical Imaging of Fluorine-18-Labeled Synaptic Vesicle Protein 2A (SV2A) PET Tracers - Constantinescu, Cristian C.; Tresse, Cedric; Zheng, MingQiang; Gouasmat, Alexandra; Carroll, Vincent M; Mistico, Laetitia; Alagille, David; Sandiego, Christine M.; Papin, Caroline; Marek, Kenneth; Seibyl, John P.; Tamagnan, Gilles D.; et al. (Molecular imaging and biology, 2019)
Keywords: Animal models; Animals; Biomarkers; Blocking; Brain; Brain - diagnostic imaging; Cyclotrons; Derivatives; Emission analysis; Enantiomers; Etiracetam; Fluorine; Fluorine isotopes; Fluorine Radioisotopes - chemistry; Imaging; In vivo methods and tests; Kinetics; Macaca fascicularis; Macaca mulatta; Medical imaging; Medicine; Medicine & Public Health; Nerve Tissue Proteins - metabolism; Neurodegenerative diseases; Neuroimaging; Neurological diseases; Occupancy; Positron emission; Positron emission tomography; Primates; Proteins; Radiation; Radiation dosage; Radioactive tracers; Radioisotopes; Radiology; Radiometry; Radiopharmaceuticals - chemistry; Reaction kinetics; Research Article; Substantia grisea; Synaptic density; Synaptic Vesicles - metabolism; Tissue Distribution; Tomography; MNI-126; Synaptic density; PET imaging; SV2A; F-18; Neurodegenerative disorders