Coxsackievirus A6 U.K. Genetic and Clinical Epidemiology Pre- and Post-SARS-CoV-2 Emergence

• Published in: Pathogens (Basel) Vol. 13; no. 11; p. 1020
• Main Authors: Joyce, Alice M, Hill, Jack D, Tsoleridis, Theocharis, Astbury, Stuart, Berry, Louise, Howson-Wells, Hannah C, Allen, Nancy, Canning, Ben, Jones, Carl B, Clark, Gemma, Irving, William L, Tarr, Alexander W, McClure, C Patrick
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 20.11.2024; MDPI
• Subjects: COVID-19; Coxsackievirus; coxsackievirus A6; Coxsackievirus infections; Coxsackieviruses; CVA6; Disease transmission; enterovirus; Epidemics; Epidemiology; Foot-and-mouth disease; Gene sequencing; genetic epidemiology; Genetic relationship; Genomes; Hand-foot-and-mouth disease; Health aspects; HFMD; Infections; Medical research; Medicine, Experimental; Meningitis; Mortality; Nucleic acids; Pandemics; Phylogenetics; Phylogeny; Severe acute respiratory syndrome coronavirus 2; Skin; Statistical analysis; Surveillance; Viral diseases; VP1 protein; United Kingdom; Europe; Japan; China; United Kingdom > UK; hand, foot and mouth disease; HFMD; enterovirus; coxsackievirus A6; CVA6; genetic epidemiology

Coxsackievirus A6 (CVA6) has become increasingly clinically relevant as a cause of Hand, Foot and Mouth Disease (HFMD) globally since 2008. However, most laboratories do not routinely determine the enteroviral type of positive samples. The non-pharmaceutical measures introduced to curb transmission...