Effector memory CD4+T cells in mesenteric lymph nodes mediate bone loss in food-allergic enteropathy model mice, creating IL-4 dominance - Ono-Ohmachi, Aiko; Yamada, Satoki; Uno, Satoru; Tamai, Masato; Soga, Kohei; Nakamura, Shotaro; Udagawa, Nobuyuki; Nakamichi, Yuko; Koide, Masanori; Morita, Yoshikazu; Takano, Tomohiro; Itoh, Takumi; et al. (Mucosal immunology, 2021)
Keywords: Allergology; Animal models; Animals; Antibodies; Biomarkers; Biomedical and Life Sciences; Biomedicine; Bone loss; Bone marrow; Bone Resorption - diagnostic imaging; Bone Resorption - etiology; Bone Resorption - metabolism; Bone Resorption - pathology; CD4 antigen; CD4-Positive T-Lymphocytes - physiology; Cytokines - genetics; Cytokines - metabolism; Diet; Disease Models, Animal; Disease Susceptibility; Effector cells; Food allergies; Food Hypersensitivity - complications; Food Hypersensitivity - immunology; Food Hypersensitivity - metabolism; Gastroenterology; Gene expression; Genetic crosses; Immunoglobulin E; Immunological memory; Immunology; Immunophenotyping; Inflammation; Interleukin 4; Interleukin-4 - genetics; Interleukin-4 - metabolism; Intestinal Diseases - complications; Intestinal Diseases - immunology; Intestinal Diseases - metabolism; Lymph nodes; Lymph Nodes - immunology; Lymph Nodes - metabolism; Lymphatic system; Lymphocytes; Lymphocytes T; Memory cells; Memory T Cells - physiology; Mesentery; Mice; Models, Biological; Monoclonal antibodies; mRNA; Osteoclasts; Osteoporosis; Ovalbumin; Spleen; Transgenes